Gene Information

Name : SPH_0458 (SPH_0458)
Accession : YP_001693868.1
Strain : Streptococcus pneumoniae Hungary19A-6
Genome accession: NC_010380
Putative virulence/resistance : Virulence
Product : tyrosine-protein kinase CpsD
Function : -
COG functional category : D : Cell cycle control, cell division, chromosome partitioning
COG ID : COG0489
EC number : 2.7.10.2
Position : 407790 - 408479 bp
Length : 690 bp
Strand : +
Note : identified by match to protein family HMM TIGR01007

DNA sequence : 
ATGCCAACGTTAGAAATCTCACAGGCGAAATTAGAACTTGTGAAAAAGGCAGAGGAATATTATAATGCTTTGTGCACGAA
CCTACAGTTAAGTGGAGATGATTTGAAAGTATTTTCTATCACTTCTGTGAAAGCAGGAGAAGGAAAAACAACGACTTCCA
CCAATATCGCTTGGGCTTTTGCGCGTGCAGGTTACAAAACGCTTCTGATTGATGCAGACATGCGTAACTCCGTTATGTCA
GGTGTCTTTAAATCAAGGGAAAGGATTACTGGACTAACAGAATTTCTATCAGGGACAACAGACCTGTCACAGGGGCTTTG
CGATACCAATATTGAGAATCTCTTTGTGATTCAGGCTGGCTCTGTGTCACCAAATCCGACAGCCCTTCTTCAAAGTAAGA
ATTTCAGTACAATGCTTGAAACCTTGCGTAAATATTTTGACTATATCGTCGTAGACACTGCCCCTGTCGGTGTCGTGATT
GATGCGGCTATCATTATGCAGAAATGTGATGCTTCTATTTTAGTGACGAAGGCAGGTGAAACAAAACGACGGGATCTTCA
AAAAGCGAAAGAACAGTTGGAACAAACTGGGAAGTCGTGTTTAGGAGTTGTGTTGAATAAACTCGATACTTCAGTAGAGA
AATACGGTTCTTATGGGAGTTATGGGAATTACAGGAAACAGAAAAAATAG

Protein sequence : 
MPTLEISQAKLELVKKAEEYYNALCTNLQLSGDDLKVFSITSVKAGEGKTTTSTNIAWAFARAGYKTLLIDADMRNSVMS
GVFKSRERITGLTEFLSGTTDLSQGLCDTNIENLFVIQAGSVSPNPTALLQSKNFSTMLETLRKYFDYIVVDTAPVGVVI
DAAIIMQKCDASILVTKAGETKRRDLQKAKEQLEQTGKSCLGVVLNKLDTSVEKYGSYGSYGNYRKQKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cpsFD YP_006310771.1 putative autophosphorylating protein tyrosine kinase Not tested FWisland_4 Protein 1e-63 64

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPH_0458 YP_001693868.1 tyrosine-protein kinase CpsD VFG1368 Protein 4e-87 81
SPH_0458 YP_001693868.1 tyrosine-protein kinase CpsD VFG1349 Protein 5e-61 55