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Name : SPH_0452 (SPH_0452) Accession : YP_001693862.1 Strain : Streptococcus pneumoniae Hungary19A-6 Genome accession: NC_010380 Putative virulence/resistance : Unknown Product : trehalose-6-phosphate hydrolase (Alpha,alpha-phosphotrehalase) Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0366 EC number : 3.2.1.93 Position : 401892 - 403499 bp Length : 1608 bp Strand : + Note : identified by match to protein family HMM PF00128 DNA sequence : ATGCAAGAAAAATGGTGGCATAATGCCGTAGTCTATCAAGTCTATCCAAAGAGTTTTATGGATAGTAATGGAGATGGAGT TGGTGATTTGCCAGGTATTACCAGTAAGTTGGACTATCTAGCTAAGCTAGGAATCACAGCGATTTGGCTTTCTCCCGTTT ATGACAGCCCTATGGATGATAATGGCTACGATATTGCTGATTATCAAGCGATTGCAACGATTTTTGGAACCATGGAGGAT ATGGATCAGCTGATTGCAGAAGCTAAGAAGCGTGACATTCGTATCATCATGGACTTGGTGGTTAATCATACCTCAGATGA ACATGCTTGGTTTGTCGAAGCCTGTGAAAATACTGATAGCCCTGAGCGAGACTACTATATCTGGCGGGATGAGCCTAACG ATTTAGATTCTATCTTTAGTGGGTCTGCTTGGGAATACGATGAAAAGTCAGGTCAATACTATCTCCACTTTTTCAGCAAG AAACAGCCGGATCTCAACTGGAAAAATGAAAAACTTCGCCAGAAAATTTATGAGATGATGAACTTCTGGATTGATAAAGG TATTGGTGGTTTCCGTATGGATGTTATTGACATGATTGGCAAAATTCCTGACGAGAAGGTAGTCAATAATGGTCCTATGC TCCATCCCTATCTCAAGGAAATGAATCAGGCGACCTTTGGAGATAAGGATCTCTTGACAGTAGGGGAGACTTGGGGAGCA ACGCCAGAGATTGCCAAGCTCTACTCTGATCCAAAGGGGCAAGAATTGTCTATGGTCTTCCAGTTTGAACATATCGGTCT TCAGTATCAGGAAGGTCAGCCTAAATGGCACTATCAAAAAGAGCTGAATATCGCTAAGTTAAAAGAAATCTTCAACAAAT GGCAGACAGAGTTAGGAGTTGAGGACGGCTGGAATTCCCTCTTCTGGAACAACCATGACCTCCCACGTATTGTCTCAATC TGGGGAAATGACCAAGAATACCGCGAAAAATCTGCCAAAGCCTTTGCAATCTTGCTTCATCTCATGAGAGGAACTCCTTA TATCTACCAAGGTGAGGAGATTGGGATGACCAACTATCCGTTTGAAACACTGGATCAAGTAGAAGATATTGAATCTCTCA ACTATGCGCGTGAGGCTCTTGAAAAAGGTGTTCCGATTGAAGAAATCATGGACAGTATCCGTGTTATTGGACGTGACAAT GCCCGTACCCCTATGCAATGGGACGAGAGCAAAAACGCTGGTTTCTCAACAGGTCAACCTTGGTTGGCGGTTAATCCAAA TTACGAGATGATCAATGTCCAAGAAGCGCTGGCAAATCCAGATTCTATTTTCTATACCTATCAGAAACTGGTCCAAATTC GCAAGGAGAATAGCTGGCTAGTTCGAGCTGACTTTGAATTGCTTGATACGGCTGATAAGGTCTTTGCTTATATACGTAAG GATGGCGACCGTCGCTTCCTAGTTGTGGCTAACTTGTCCAATGAAGAGCAAGACTTGACAGTAGAAGGAAAAGTCAAATC TGTCTTGATTGAAAACACTGCGGCTAAAGAAGTACTTGAAAAACAGGTCTTGGCTCCATGGGATGCTTTCTGTGTGGAAT TACTATAA Protein sequence : MQEKWWHNAVVYQVYPKSFMDSNGDGVGDLPGITSKLDYLAKLGITAIWLSPVYDSPMDDNGYDIADYQAIATIFGTMED MDQLIAEAKKRDIRIIMDLVVNHTSDEHAWFVEACENTDSPERDYYIWRDEPNDLDSIFSGSAWEYDEKSGQYYLHFFSK KQPDLNWKNEKLRQKIYEMMNFWIDKGIGGFRMDVIDMIGKIPDEKVVNNGPMLHPYLKEMNQATFGDKDLLTVGETWGA TPEIAKLYSDPKGQELSMVFQFEHIGLQYQEGQPKWHYQKELNIAKLKEIFNKWQTELGVEDGWNSLFWNNHDLPRIVSI WGNDQEYREKSAKAFAILLHLMRGTPYIYQGEEIGMTNYPFETLDQVEDIESLNYAREALEKGVPIEEIMDSIRVIGRDN ARTPMQWDESKNAGFSTGQPWLAVNPNYEMINVQEALANPDSIFYTYQKLVQIRKENSWLVRADFELLDTADKVFAYIRK DGDRRFLVVANLSNEEQDLTVEGKVKSVLIENTAAKEVLEKQVLAPWDAFCVELL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| malL | YP_251987.1 | oligosaccharide alpha-1,6-glucosidase | Not tested | SCCmec | Protein | 4e-123 | 50 |
