Gene Information

Name : SPH_0252 (SPH_0252)
Accession : YP_001693670.1
Strain : Streptococcus pneumoniae Hungary19A-6
Genome accession: NC_010380
Putative virulence/resistance : Virulence
Product : UDP-glucose 6-dehydrogenase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1004
EC number : 1.1.1.22
Position : 220966 - 222138 bp
Length : 1173 bp
Strand : +
Note : identified by match to protein family HMM PF00984; match to protein family HMM PF03721; match to protein family HMM TIGR03026

DNA sequence :
ATGAATATAGCAGTAATTGGTTTGGGGCATGTTGGGCTGGCCTACGCGTTACTATTTGCATCTAAATATAAAGTTGTTGC
ATATGATATAGATTCTGTAAAAATAAATAATTTAAAAAAGGGCATTCTTCCATCTAAAAATGAAGAGCTTATGAAGTTTT
TTTGCGAGAATAACTTAAATATTACTTTTTTTGATACATTTTCTGAAATTAAAAATAATATTGATTATTATATTATTGCG
CTTCCGACAGATTATGATGAGAAAATTGGTAGTTTTAATACATATGAAATCGAACAAACGGTATCGAAGATTCTGAGGGT
AAAACCTAATGGAAAGATTATTTTAAAGTCAACAGTTCCGATCGGCTTTTCAAACAAATTAAAAAGGCTGTTTGATACAA
AAAATATCATTTTTGTCCCTGAATTTTTGAGAGAAGGTTGTTCTATATATGATAATTTATATCCAAGTCGCATAGTTGTT
GGAGATGAGACAGTTGAAGGAAGAAAAATTGCAGAGTTGTTCCTTTCGATTAGTACTCATAGTACTGCCAATATTAAAAA
TGTTATGTTAGTTTCTCCTACTGAAGCAGAAGCAATTAAGCTTTTTTCTAACACATTCTTAGCTCTCCGTGTTGCTTTTT
TTAATGAACTAGATTCTTTTGCTGAGAGGAGAAGTTTAAATGCTGAAGTTGTAATAAAAGGTGTTTGTTTAGATCCAAGA
ATTGGAAATTTTTATAATAATCCTTCTTTTGGATTTGGAGGATATTGTCTTCCCAAAGATACTAAACAATTAAAAAAAGA
ATTTATAGAAATAAATGCCCCAGTGATAGAAGCGATTGATATTTCAAACACAAATAGAAAACAGTTCATAGTTAAACAAA
TATTGGAACGAAAGCCAAAGATAGTAGGAATATATAAATTGGGGATGAAATATAATTCAGATAATTACAAAGAGTCAGCT
ATTTTAAGTATAATTAATGAACTATTGATTGTCGGTATAAAAATTTTAGTATATGAACCAAATTTAAACGTTAGTATAGA
TAACGTAATTTTTGAAAAGAATTTTGAACTATTTATAAAACAAAGTGATCTAATTGTTGCAAATAGATGGGATAGGGGCC
TTGAAGCTTATAAAGATAAAGTTTACACAAGGGGGATCTGGATAAGAGATTAA

Protein sequence :
MNIAVIGLGHVGLAYALLFASKYKVVAYDIDSVKINNLKKGILPSKNEELMKFFCENNLNITFFDTFSEIKNNIDYYIIA
LPTDYDEKIGSFNTYEIEQTVSKILRVKPNGKIILKSTVPIGFSNKLKRLFDTKNIIFVPEFLREGCSIYDNLYPSRIVV
GDETVEGRKIAELFLSISTHSTANIKNVMLVSPTEAEAIKLFSNTFLALRVAFFNELDSFAERRSLNAEVVIKGVCLDPR
IGNFYNNPSFGFGGYCLPKDTKQLKKEFIEINAPVIEAIDISNTNRKQFIVKQILERKPKIVGIYKLGMKYNSDNYKESA
ILSIINELLIVGIKILVYEPNLNVSIDNVIFEKNFELFIKQSDLIVANRWDRGLEAYKDKVYTRGIWIRD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0068 YP_300158.1 UDP-glucose 6-dehydrogenase Not tested SCC15305cap Protein 8e-72 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPH_0252 YP_001693670.1 UDP-glucose 6-dehydrogenase VFG0963 Protein 2e-70 45