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Name : SPH_2393 (SPH_2393) Accession : YP_001695552.1 Strain : Streptococcus pneumoniae Hungary19A-6 Genome accession: NC_010380 Putative virulence/resistance : Virulence Product : chaperone ClpB 1 Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 2202101 - 2204533 bp Length : 2433 bp Strand : - Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728 DNA sequence : ATGAACTATTCAAAAGCATTGAATGAATGTATCGAAAGTGCCTACATGGTTGCTGGACATTTTGGAGCTCGTTATCTAGA GTCTTGGCACTTGTTGATTGCCATGTCTAATCACAGTTATAGTGTAGCAGGGGCAACTTTAAATGATTATCCGTATGAGA TGGACCGTTTAGAAGAGGTGGCTTTGGAACTGACTGAAACGGACTATAGCCAGGATGAAACCTTTACGGAATTGCCGTTC TCCCGTCGTTTGCAGGTTCTTTTTGACGAAGCAGAGTATGTAGCGTCAGTGGTCCATGCTAAGGTGCTAGGGACAGAGCA CGTCCTCTATGCGATTTTGCATGATGGCAATGCCTTGGCGACTCGTATCTTGGAGAGGGCTGGATTTTCTTATGAAGACA AGAAAGATCAGGTCAAGATTGCTGCTCTTCGTCGAAATTTAGAAGAACGGGCAGGCTGGACTCGTGAAGATCTCAAGGCT TTACGCCAACGCCATCGTACAGTAGCTGACAAGCAAAATTCTATGGCCAATATGATGGGCATGCCGCAGACTCCTAGTGG AGGTCTCGAGGACTATACGCATGATTTGACAGAGCAAGCGCGTTCTGGCAAGTTAGAACCAGTCATCGGTCGGGACAAGG AAATCTCACGTATGATTCAAATCTTGAGCCGGAAGACTAAGAACAACCCTGTCTTGGTTGGGGATGCTGGTGTCGGGAAA ACAGCTCTGGCGCTTGGTCTTGCTCAGCGTATTGCTAGTGGTGACGTGTCTGCGGAAATGGCTAAGATGCGCGTGTTAGA ACTTGATTTGATGAATGTCGTTGCAGGGACACGCTTCCGTGGTGACTTTGAAGAACGCATGAATAATATCATCAAGGATA TTGAAGAAGATGGCCAAGTCATCCTCTTTATCGATGAACTCCACACCATCATGGGTTCTGGTAGCGGGATTGATTCGACT CTGGATGCGGCCAATATCTTGAAACCAGCCTTGGCGCGTGGAACTTTGAGAACGGTTGGTGCCACCACTCAGGAAGAATA TCAAAAACATATCGAAAAAGATGCGGCTCTTTCTCGTCGTTTCGCTAAAGTGACGATTGAAGAACCAAGTGTGGCAGATA GTATGACTATTTTACAAGGTTTGAAGGCGACTTATGAGAAACATCACCGTGTACAAATCACAGATGAAGCGGTTGAAACA GCGGTTAAGATGGCTCATCGTTATTTAACCAGTCGTCACTTGCCAGACTCTGCTATCGACCTCTTGGACGAAGCAGCAGC AACAGTGCAAAATAAGGCAAATCATGTAAAAGCAGACGATTCAGATTTGAGTCCAGCTGACAAGGCCCTGATGGATGGCA AGTGGAAACAGGCAGCCCAGCTAATCGCAAAAGAAGAGGAAGTACCTGTCTACAAAGACTTGGTGACAGAGTCTGATATT TTGACCACCTTGAGTCGCTTGTCAGGAATCCCAGTTCAAAAACTGACTCAAACGGATGCTAAGAAGTATTTAAATCTTGA AGCAGAACTCCATAAACGGGTTATCGGTCAAGATCAAGCTGTTTCAAGTATTAGTCGTGCCATTCGCCGTAATCAGTCAG GAATTCGCAGTCACAAGCGTCCGATCGGTTCCTTTATGTTCCTAGGACCCACAGGTGTCGGTAAGACCGAGTTGGCCAAG GCTTTGGCAGAAGTTCTCTTTGATGACGAATCAGCCCTTATCCGCTTTGATATGAGTGAGTATATGGAGAAATTCGCAGC CAGCCGTCTAAATGGAGCTCCTCCAGGCTATGTGGGTTACGAAGAAGGTGGGGAGTTGACAGAGAAGGTTCGCAATAAAC CCTATTCCGTTCTCCTCTTTGATGAGGTAGAGAAGGCTCACCCAGATATCTTTAATGTTCTCTTGCAGGTTCTGGATGAC GGTGTCTTGACAGATAGCAAGGGACGCAAGGTCGATTTTTCAAATACCATTATCATTATGACATCGAATCTAGGTGCGAC TGCCCTTCGTGATGATAAGACTGTTGGTTTTGGGGCTAAGGATATTCGTTTTGACCAGGAAAATATGGAAAAACGCATGT TTGAAGAACTGAAAAAAGCTTATAGACCGGAATTCATCAACCGTATTGATGAGAAGGTGGTCTTCCATAGCCTATCTAGT GACCATATGCAGGAAGTGGTGAAGATTATGGTCAAGCCTTTAGTGGCAAGTTTGGCTGAAAAAGGCATTGACTTGAAATT ACAAGCTTCAGCTCTGAAATTGTTAGCAAATCAAGGATATGACCCAGAGATGGGAGCTCGCCCACTTCGCAGAACCCTGC AAACAGAAGTGGAGGACAAGTTGGCAGAACTTCTTCTCAAGGGAGATTTAGTGGCAGGCAGCACACTTAAGATTGGTGTC AAAGCAGGCCAGTTAAAATTTGATATTGCATAA Protein sequence : MNYSKALNECIESAYMVAGHFGARYLESWHLLIAMSNHSYSVAGATLNDYPYEMDRLEEVALELTETDYSQDETFTELPF SRRLQVLFDEAEYVASVVHAKVLGTEHVLYAILHDGNALATRILERAGFSYEDKKDQVKIAALRRNLEERAGWTREDLKA LRQRHRTVADKQNSMANMMGMPQTPSGGLEDYTHDLTEQARSGKLEPVIGRDKEISRMIQILSRKTKNNPVLVGDAGVGK TALALGLAQRIASGDVSAEMAKMRVLELDLMNVVAGTRFRGDFEERMNNIIKDIEEDGQVILFIDELHTIMGSGSGIDST LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVTIEEPSVADSMTILQGLKATYEKHHRVQITDEAVET AVKMAHRYLTSRHLPDSAIDLLDEAAATVQNKANHVKADDSDLSPADKALMDGKWKQAAQLIAKEEEVPVYKDLVTESDI LTTLSRLSGIPVQKLTQTDAKKYLNLEAELHKRVIGQDQAVSSISRAIRRNQSGIRSHKRPIGSFMFLGPTGVGKTELAK ALAEVLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNKPYSVLLFDEVEKAHPDIFNVLLQVLDD GVLTDSKGRKVDFSNTIIIMTSNLGATALRDDKTVGFGAKDIRFDQENMEKRMFEELKKAYRPEFINRIDEKVVFHSLSS DHMQEVVKIMVKPLVASLAEKGIDLKLQASALKLLANQGYDPEMGARPLRRTLQTEVEDKLAELLLKGDLVAGSTLKIGV KAGQLKFDIA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| clpC | YP_005163377.1 | ATP-dependent Clp protease ATP-binding subunit | Not tested | Not named | Protein | 1e-140 | 49 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| SPH_2393 | YP_001695552.1 | chaperone ClpB 1 | VFG0079 | Protein | 1e-160 | 47 |
| SPH_2393 | YP_001695552.1 | chaperone ClpB 1 | VFG0080 | Protein | 2e-125 | 43 |
