Gene Information

Name : SPH_0213 (SPH_0213)
Accession : YP_001693633.1
Strain : Streptococcus pneumoniae Hungary19A-6
Genome accession: NC_010380
Putative virulence/resistance : Resistance
Product : macrolide export ATP-binding/permease MacB
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1136
EC number : 3.6.3.-
Position : 186793 - 187434 bp
Length : 642 bp
Strand : +
Note : identified by match to protein family HMM PF00005

DNA sequence : 
ATGATTGAGTTGAAAAATATTACCAAAACCATTGGGGGAAAAGTGATTTTGGATAACTTATCTCTCAGGATTGATCAGGG
GGATTTGGTAGCTATTGTTGGTAAGAGTGGTAGTGGGAAGTCGACCTTGTTAAATTTATTGGGTTTGATAGATGGTGATT
ATAGCGGACGGTATGAGATTTTTGGTCAGACAAATCTAGCGGTTAATTCTGCTAAGTCGCAAACAATAATCCGTGAACAT
ATCTCTTATCTGTTTCAAAATTTTGCCCTGATTGATGATGAAACGGTCGAGTACAATCTCATGCTGGCGCTGAAATATGT
GAAATTGCCTAAGAAAGACAAGCTCAAAAAGGTGGAAGAGATTTTAGAGAGAGTAGGTTTGTCAGCTACTTTGCATCAAA
GGGTCTCCGAGTTGTCTGGGGGCGAACAACAACGAATTGCAGTTGCTAGAGCCATCTTAAAACCCAGCCAGCTGATTTTA
GCCGATGAACCTACAGGTTCGCTGGATCCTGAAAATAGAGATTTGGTCTTGAAGTTTCTCTTAGAGATGAATCGAGAAGG
GAAAACAGTCATTATTGTGACCCACGATGCTTATGTAGCCCAACAATGTCATCGTGTCATTGAATTGGGCGAGGGAAAAT
GA

Protein sequence : 
MIELKNITKTIGGKVILDNLSLRIDQGDLVAIVGKSGSGKSTLLNLLGLIDGDYSGRYEIFGQTNLAVNSAKSQTIIREH
ISYLFQNFALIDDETVEYNLMLALKYVKLPKKDKLKKVEEILERVGLSATLHQRVSELSGGEQQRIAVARAILKPSQLIL
ADEPTGSLDPENRDLVLKFLLEMNREGKTVIIVTHDAYVAQQCHRVIELGEGK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Spaf_1862 YP_006310627.1 amino acid ABC transporter ATP-binding protein Not tested FWisland_2 Protein 3e-51 61

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPH_0213 YP_001693633.1 macrolide export ATP-binding/permease MacB NC_012469.1.7686946. Protein 1e-86 100
SPH_0213 YP_001693633.1 macrolide export ATP-binding/permease MacB CP003583.1.gene613.p Protein 5e-31 45