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Name : SPH_2065 (SPH_2065) Accession : YP_001695281.1 Strain : Streptococcus pneumoniae Hungary19A-6 Genome accession: NC_010380 Putative virulence/resistance : Virulence Product : pneumolysin (Thiol-activated cytolysin) Function : - COG functional category : - COG ID : - EC number : - Position : 1902996 - 1904411 bp Length : 1416 bp Strand : - Note : identified by match to protein family HMM PF01289 DNA sequence : ATGGCAAATAAAGCAGTAAATGACTTTATACTAGCTATGAATTACGATAAAAAGAAACTCTTGACCCATCAGGGAGAAAG TATTGAAAATCGTTTCATCAAAGAGGGTAATCAGCTACCCGATGAGTTTGTTGTTATCGAAAGAAAGAAGCGGAGCTTGT CGACAAATACAAGTGATATTTCTGTAACAGCTACCAACGACAGTCGCCTCTATCCTGGAGCACTTCTCGTAGTGGATGAG ACCTTGTTAGAGAATAATCCCACTCTTCTTGCGGTCGATCGTGCTCCGATGACTTATAGTATTGATTTGCCTGGTTTGGC AAGTAGCGATAGCTTTCTCCAAGTGGAAGACCCCAGCAATTCGAGTGTTCGCGGAGCGGTAAACGATTTGTTGGCTAAGT GGCATCAAGATTATGGTCAGGTCAATAATGTCCCAGCTAGAATGCAGTATGAAAAAATCACGGCTCACAGCATGGAACAA CTCAAGGTCAAGTTTGGTTCTGACTTTGAAAAGACAGGGAATTCTCTTGATATTGATTTTAACTCTGTCCATTCAGGCGA AAAGCAGATTCAGATTGTTAATTTTAAGCAGATTTATTATACAGTCAGCGTAGATGCTGTTAAAAATCCAGGAGATGTGT TTCAAGATACTGTAACGGTAGAGGATTTAAAACAGAGAGGAATTTCTGCAGAGCGTCCTTTGGTCTATATTTCGAGTGTT GCTTATGGGCGCCAAGTCTATCTCAAGTTGGAAACCACGAGTAAGAGTGATGAAGTAGAGGCTGCTTTTGAAGCTTTGAT AAAAGGAGTCAAGGTAGCTCCTCAGACAGAGTGGAAGCAGATTTTGGACAATACAGAAGTGAAGGCGGTTATTTTAGGGG GCGACCCAAGTTCGGGTGCCCGAGTTGTAACAGGCAAGGTGGATATGGTAGAGGACTTGATTCAAGAAGGCAGTCGCTTT ACAGCAGATCATCCAGGCTTGCCGATTTCCTATACAACTTCTTTTTTACGTGACAATGTAGTTGCGACCTTTCAAAACAG TACAGACTATGTTGAGACTAAGGTTACAGCTTACAGAAACGGAGATTTACTGCTGGATCATAGTGGTGCCTATGTTGCCC AATATTATATTACTTGGGATGAATTATCCTATGATCATCAAGGTAAGGAAGTCTTGACTCCTAAGGCTTGGGACAGAAAT GGGCAGGATTTGACGGCTCACTTTACCACTAGTATTCCTTTAAAAGGGAATGTTCGTAATCTCTCTGTCAAAATTAGAGA GTGTACCGGGCTTGCCTGGGAATGGTGGCGTACGGTTTATGAAAAAACCGATTTGCCACTAGTGCGTAAGCGGACGATTT CTATTTGGGGAACAACTCTCTATCCGCAGGTAGAAGATAAGGTAGAAAATGACTAG Protein sequence : MANKAVNDFILAMNYDKKKLLTHQGESIENRFIKEGNQLPDEFVVIERKKRSLSTNTSDISVTATNDSRLYPGALLVVDE TLLENNPTLLAVDRAPMTYSIDLPGLASSDSFLQVEDPSNSSVRGAVNDLLAKWHQDYGQVNNVPARMQYEKITAHSMEQ LKVKFGSDFEKTGNSLDIDFNSVHSGEKQIQIVNFKQIYYTVSVDAVKNPGDVFQDTVTVEDLKQRGISAERPLVYISSV AYGRQVYLKLETTSKSDEVEAAFEALIKGVKVAPQTEWKQILDNTEVKAVILGGDPSSGARVVTGKVDMVEDLIQEGSRF TADHPGLPISYTTSFLRDNVVATFQNSTDYVETKVTAYRNGDLLLDHSGAYVAQYYITWDELSYDHQGKEVLTPKAWDRN GQDLTAHFTTSIPLKGNVRNLSVKIRECTGLAWEWWRTVYEKTDLPLVRKRTISIWGTTLYPQVEDKVEND |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hly | AAA69525.1 | listeriolysin O | Virulence | LIPI-1 | Protein | 4e-107 | 44 |
| slo | YP_281505.1 | streptolysin O | Virulence | Not named | Protein | 6e-97 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| SPH_2065 | YP_001695281.1 | pneumolysin (Thiol-activated cytolysin) | VFG1363 | Protein | 0.0 | 99 |
| SPH_2065 | YP_001695281.1 | pneumolysin (Thiol-activated cytolysin) | VFG2275 | Protein | 2e-110 | 47 |
| SPH_2065 | YP_001695281.1 | pneumolysin (Thiol-activated cytolysin) | VFG0074 | Protein | 5e-108 | 44 |
| SPH_2065 | YP_001695281.1 | pneumolysin (Thiol-activated cytolysin) | VFG0976 | Protein | 2e-97 | 43 |
