Gene Information

Name : SPH_1870 (SPH_1870)
Accession : YP_001695134.1
Strain : Streptococcus pneumoniae Hungary19A-6
Genome accession: NC_010380
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 1726791 - 1729163 bp
Length : 2373 bp
Strand : -
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
GTGTTTAGACGTTTAGGTCAAGATTTCCAGCTTAGGAAAGTGAAAAAGATTTTAAAGCAGATTAATGCCCTGAAAGGCAA
GATGTCCTCTCTTTCGGATCAAGAATTAGTAGCTAAAACAGTAGAGTTTCGTCAGCGTCTTTCCGAGGGAGAAAGTCTAG
ACGATATTTTGGTTGAAGCTTTTGCTGTGGTGCGTGAAGCAGATAAGCGGATTTTAGGGATGTTCCCCTATGATGTTCAA
GTCATGGGAGCTATTGTCATGCACTATGGAAATGTTGCTGAGATGAATACGGGGGAAGGTAAGACCTTGACAGCTACCAT
GCCTGTCTATTTGAACGCTTTTTCAGGAGAAGGAGTGATGGTTGTGACTCCTAATGAGTATTTATCAAAGCGTGATGCCG
AGGAAATGGGCCAAGTTTATCGTTTTCTAGGATTGACCATTGGTGTACCATTTACGGAAGATCCAAAGAAGGAAATGAAA
GCTGAAGAAAAGAAGCTTATCTATGCTTCGGATATCATCTACACAACCAATAGTAATTTAGGTTTTGATTATCTAAATGA
TAACCTAGCCTCGAATGAAGAAGGTAAGTTTTTACGACCGTTTAACTATGTGATTATTGATGAAATTGATGATATCTTGC
TTGATAGTGCACAAACTCCTCTGATTATTGCGGGTTCTCCTCGTGTTCAGTCTAATTACTATGCGATCATTAATACACTT
GTAACAACCTTGGTCGAAGGAGAGGATTATATCTTTAAAGAGGAGAAAGAGGAGGTTTGGCTCACTACTAAGGGGGCCAA
GTCTGCTGAGAATTTCCTAGGGATTGATAATTTATACAAGGAAGAGCATGCGTCTTTTGCTCGTCATTTGGTTTATGCGA
TTCGAGCTCATAAGCTCTTTACTAAAGATAAGGACTATATCATTCGTGGAAATGAGATGGTACTGGTTGATAAGGGAACA
GGGCGTCTAATGGAAATGACTAAACTTCAAGGAGGTCTCCATCAGGCTATTGAAGCCAAGGAACATGTCAAATTATCTCC
TGAGACGCGGGCTATGGCCTCGATCACCTATCAGAGTCTTTTTAAGATGTTTAATAAGATATCTGGTATGACAGGGACAG
GTAAGGTCGCGGAAAAAGAGTTTATTGAAACTTATAATATGTCTGTAGTACGCATTCCAACCAATCGTCCGAGACAACGG
ATTGACTATCCAGATAATCTATATATCACTTTACCTGAAAAAGTGTATGCATCCTTGGAGTACATCAAGCAATACCATGC
TAAGGGAAATCCCTTACTCGTTTTTGTAGGCTCAGTTGAAATGTCTCAACTCTATTCGTCTCTCTTGTTTCGTGAAGGGA
TTGCCCATAATGTCCTAAATGCTAATAATGCGGCGCGTGAGGCTCAGATTATCTCCGAGTCAGGTCAGATGGGGGCTGTG
ACAGTGGCTACCTCTATGGCAGGACGTGGTACGGATATCAAGCTTGGTAAAGGAGTTGCAGAGCTTGGGGGCTTGATTGT
TATTGGGACTGAGCGAATGGAAAGTCAGCGGATCGACCTACAAATTCGTGGCCGTTCTGGTCGTCAGGGAGATCCTGGTA
TGAGTAAATTTTTTGTATCCTTAGAGGATGATGTTATCAAGAAGTTTGGTCCATCTTGGGTGCATAAAAAGTACAAAGAC
TATCAGGTTCAAGATATGACTCAACCGGAAGTATTGAAAGGTCGTAAATACCGGAAACTAGTCGAAAAGGCTCAGCATGC
CAGTGATAGTGCTGGACGTTCAGCACGTCGTCAGACTCTGGAGTATGCTGAAAGTATGAATATACAACGGGATATAGTCT
ATAAAGAGAGAAATCGTCTAATAGATGGTTCTCGTGACTTAGAGGATGTTGTTGTGGATATCATTGAGAGATATACAGAA
GAGGTAGCGGCTGATCACTATGCTAGTCGTGAATTATTGTTTCACTTTATTGTGACCAATATTAGTTTTCATGTTAAAGA
GGTTCCAGATTATATAGATGTAACTGACAAAACTGCAGTTCGTAGCTTTATGAAGCAGGTGATTGATAAAGAACTTTCTG
AAAAGAAAGAATTACTTAATCAACATGACTTATATGAACAGTTTTTACGACTTTCACTGCTTAAAGCCATTGATGACAAC
TGGGTAGAGCAGGTAGACTATCTACAACAGCTATCCATGGCTATCGGTGGTCAATCTGCTAGTCAGAAAAATCCAATCGT
AGAGTACTATCAAGAAGCCTACGCGGGCTTTGAAGCTATGAAAGAACAAATCCGTGCGGATATGGTGCGTAATCTCCTGA
TGGGGCTGGTTGAGGTCACTCCAAAAGGTGAAATCGTGACTCATTTTCCATAA

Protein sequence :
MFRRLGQDFQLRKVKKILKQINALKGKMSSLSDQELVAKTVEFRQRLSEGESLDDILVEAFAVVREADKRILGMFPYDVQ
VMGAIVMHYGNVAEMNTGEGKTLTATMPVYLNAFSGEGVMVVTPNEYLSKRDAEEMGQVYRFLGLTIGVPFTEDPKKEMK
AEEKKLIYASDIIYTTNSNLGFDYLNDNLASNEEGKFLRPFNYVIIDEIDDILLDSAQTPLIIAGSPRVQSNYYAIINTL
VTTLVEGEDYIFKEEKEEVWLTTKGAKSAENFLGIDNLYKEEHASFARHLVYAIRAHKLFTKDKDYIIRGNEMVLVDKGT
GRLMEMTKLQGGLHQAIEAKEHVKLSPETRAMASITYQSLFKMFNKISGMTGTGKVAEKEFIETYNMSVVRIPTNRPRQR
IDYPDNLYITLPEKVYASLEYIKQYHAKGNPLLVFVGSVEMSQLYSSLLFREGIAHNVLNANNAAREAQIISESGQMGAV
TVATSMAGRGTDIKLGKGVAELGGLIVIGTERMESQRIDLQIRGRSGRQGDPGMSKFFVSLEDDVIKKFGPSWVHKKYKD
YQVQDMTQPEVLKGRKYRKLVEKAQHASDSAGRSARRQTLEYAESMNIQRDIVYKERNRLIDGSRDLEDVVVDIIERYTE
EVAADHYASRELLFHFIVTNISFHVKEVPDYIDVTDKTAVRSFMKQVIDKELSEKKELLNQHDLYEQFLRLSLLKAIDDN
WVEQVDYLQQLSMAIGGQSASQKNPIVEYYQEAYAGFEAMKEQIRADMVRNLLMGLVEVTPKGEIVTHFP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 0.0 50