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Name : secA (SPH_1806) Accession : YP_001695078.1 Strain : Streptococcus pneumoniae Hungary19A-6 Genome accession: NC_010380 Putative virulence/resistance : Unknown Product : preprotein translocase subunit SecA Function : - COG functional category : U : Intracellular trafficking, secretion and vesicular transport COG ID : COG0653 EC number : - Position : 1672117 - 1674630 bp Length : 2514 bp Strand : - Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap DNA sequence : ATGGCTAATATTTTAAAAACAATTATCGAAAATGATAAAGGAGAAATCCGTCGTCTGGAAAAGATGGCTGACAAGGTTTT CAAATACGAAGACCAAATGGCTGCTTTGACAGATGACCAACTAAAAGCAAAAACAGTTGAATTTAAAGAACGTTATCAAA ATGGAGAATCACTGGATTCATTGCTTTATGAAGCATTTGCGGTTGTCCGTGAGGGTGCTAAACGTGTCCTAGGACTCTTC CCATATAAGGTTCAGGTCATGGGGGGAATCGTTCTTCACCATGGTGACGTGCCAGAGATGCGTACAGGGGAAGGGAAAAC CTTGACTGCGACCATGCCCGTATACCTCAACGCCCTTTCAGGTAAAGGGGTTCACGTAGTTACAGTCAATGAATACCTAT CAGAACGTGACGCGACTGAGATGGGTGAATTGTACTCTTGGCTTGGTTTGTCAGTAGGAATCAACTTGGCTGCCAAATCT CCAATGGAGAAAAAAGAAGCCTATGAGTGTGACATTACCTACTCAACCAACTCAGAAATCGGATTTGACTACCTTCGTGA CAACATGGTCGTTCGTGCTGAAAACATGGTACAACGTCCGCTTAACTATGCCTTGGTCGATGAGGTTGACTCTATCTTGA TTGATGAGGCGCGTACACCTTTGATCGTATCAGGTGCTAATGCGGTTGAAACTAGTCAGCTCTACCACATGGCAGACCAC TATGTGAAATCTTTGGACAAAGACGACTACATCATCGATGTGCAGTCTAAGACTATTGGTTTGTCTGATTCAGGGATTGA CAAGGCGGAAAGCTACTTCAAACTGGAAAATCTCTATGACATCGAAAACGTAGCTCTGACTCACTTTATCGATAATGCCC TTCGTGCCAACTACATCATGCTTCTCGATATTGACTATGTGGTAAGCGAAGAGCAAGAAATCTTGATTGTCGACCAATTT ACAGGTCGTACTATGGAAGGTCGTCGTTATTCTGATGGATTGCACCAAGCTATTGAAGCTAAAGAAGGTGTGCCAATTCA GGATGAAACCAAGACATCTGCCTCAATCACTTACCAAAATCTTTTCCGTATGTACAAGAAATTGTCTGGTATGACGGGTA CTGGTAAGACTGAGGAAGAAGAATTCCGTGAAATTTACAACATTCGTGTTATTCCAATCCCAACAAACCGTCCTGTTCAA CGTATTGACCACTCAGACCTTCTTTATGCAAGTATCGAGGCTAAGTTTAAGGCAGTTGTCGAAGACGTTAAGGCTCGTTA CCAAAAAGGTCAGCCTGTCTTGGTTGGTACAGTAGCGGTTGAAACCAGTGATTACATTTCTAAGAAATTGGTCGCAGCTG GCGTTCCTCACGAAGTCTTGAATGCCAAAAACCATTATAGAGAAGCCCAAATTATCATGAATGCTGGGCAACGAGGTGCC GTTACCATCGCAACCAACATGGCCGGTCGTGGTACCGACATCAAGCTTGGTGAAGGGGTTCGTGAACTTGGAGGACTTTG TGTGATTGGTACAGAGCGCCATGAAAGCCGTCGTATCGATAACCAGCTTCGTGGACGTTCAGGTCGTCAAGGAGATCCAG GTGAGTCACAATTCTACCTCTCTCTTGAAGATGATTTGATGAAACGTTTTGGTTCTGAACGCTTGAAGGGAATCTTTGAA CGTCTCAACATGTCTGAAGAGGCGATTGAGTCTCGCATGTTGACGCGTCAGGTTGAAGCAGCTCAGAAACGTGTCGAAGG AAATAACTACGATACTCGTAAACAAGTCCTTCAATACGATGATGTCATGCGTGAACAACGTGAGATTATCTACGCTCAAC GTTACGACGTCATCACTGCAGACCGTGACTTGGCACCTGAAATTCAGGCTATGATCAAACGCACGATTGGTCGTGTCGTT GATGGTCATGCGCGTGCCAAACAAGATGAAAAACTAGAGGCAATTTTGAACTTTGCTAAGTACAACTTGCTTCCAGAAGA TTCTATTACGATGGAAGATTTGTCTGGCTTGTCTGATAAGGCCATCAAGGAAGAGCTTTTCCAACGTGCCTTGCAAGTTT ACGATAGTCAGGTTTCAAAACTACGCGATGAAGAAGCAGTTAAAGAATTCCAAAAAGTCTTGATTCTACGAGTGGTAGAT AACAAGTGGACAGATCATATCGATGCCCTCGATCAACTGCGTAACGCGGTTGGACTTCGTGGCTATGCTCAGAACAATCC TGTTGTTGAGTATCAGGCAGAAGGTTTCCGTATGTTTAATGACATGATTGGTTCGATTGAGTTTGATGTGACACGCTTGA TGATGAAAGCACAAATTCATGAACAAGAAAGACCACAAGCAGAACACCATATCAGTACAACAGCGACTCGCAATATCGCT GCCCACCAGGCAAATATGCCAGAAGATTTGGATTTGAGCCAAATTGGACGGAATGAACTTTGCCCATGTGGTTCTGGTAA GAAGTTTAAAAACTGTCACGGAAAAAGACAATAA Protein sequence : MANILKTIIENDKGEIRRLEKMADKVFKYEDQMAALTDDQLKAKTVEFKERYQNGESLDSLLYEAFAVVREGAKRVLGLF PYKVQVMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALSGKGVHVVTVNEYLSERDATEMGELYSWLGLSVGINLAAKS PMEKKEAYECDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGANAVETSQLYHMADH YVKSLDKDDYIIDVQSKTIGLSDSGIDKAESYFKLENLYDIENVALTHFIDNALRANYIMLLDIDYVVSEEQEILIVDQF TGRTMEGRRYSDGLHQAIEAKEGVPIQDETKTSASITYQNLFRMYKKLSGMTGTGKTEEEEFREIYNIRVIPIPTNRPVQ RIDHSDLLYASIEAKFKAVVEDVKARYQKGQPVLVGTVAVETSDYISKKLVAAGVPHEVLNAKNHYREAQIIMNAGQRGA VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDDLMKRFGSERLKGIFE RLNMSEEAIESRMLTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAQRYDVITADRDLAPEIQAMIKRTIGRVV DGHARAKQDEKLEAILNFAKYNLLPEDSITMEDLSGLSDKAIKEELFQRALQVYDSQVSKLRDEEAVKEFQKVLILRVVD NKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQAEGFRMFNDMIGSIEFDVTRLMMKAQIHEQERPQAEHHISTTATRNIA AHQANMPEDLDLSQIGRNELCPCGSGKKFKNCHGKRQ |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| secA2 | YP_006310687.1 | preprotein translocase subunit SecA2 | Not tested | FWisland_3 | Protein | 5e-140 | 42 |
