Gene Information

Name : SPH_1759 (SPH_1759)
Accession : YP_001695035.1
Strain : Streptococcus pneumoniae Hungary19A-6
Genome accession: NC_010380
Putative virulence/resistance : Virulence
Product : manganese ABC transporter substrate-binding lipoprotein (adhesin B) (Saliva-binding protein)
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG0803
EC number : -
Position : 1620004 - 1620933 bp
Length : 930 bp
Strand : +
Note : identified by match to protein family HMM PF01297

DNA sequence :
ATGAAAAAATTAGGTACATTACTCGTTCTCTTTCTTTCTGCAATCATTCTTGTAGCATGTGCTAGCGGAAAAAAAGATAC
AACTTCTGGTCAAAAACTAAAAGTTGTTGCTACAAACTCAATCATCGCTGATATTACTAAAAATATTGCTGGTGACAAAA
TTGACCTTCATAGTATCGTTCCGATTGGGCAAGACCCACACGAATACGAACCACTTCCTGAAGACGTTAAGAAAACTTCT
GAGGCTGATTTGATTTTCTATAACGGTATCAACCTTGAAACAGGTGGCAATGCTTGGTTTACAAAATTGGTAGAAAATGC
CAAGAAAACTGAAAACAAAGACTACTTCGCAGTCAGCGACGGCGTTGATGTTATCTACCTTGAAGGTCAAAATGAAAAAG
GAAAAGAAGACCCACACGCTTGGCTTAACCTTGAAAACGGTATTATTTTTGCTAAAAATATCGCCAAACAATTGAGCGCC
AAAGACCCTAACAATAAAGAATTCTATGAAAAAAATCTCAAAGAATATACTGATAAGTTAGACAAACTTGATAAAGAAAG
TAAGAATAAATTTAATAAGATCCCTGCTGAAAAGAAACTCATTGTAACCAGCGAAGGAGCATTCAAATACTTCTCTAAAG
CCTATGGTGTCCCAAGTGCCTACATCTGGGAAATCAATACTGAAGAAGAAGGAACTCCTGAACAAATCAAGACCTTGGTT
GAAAAACTTCGCCAAACAAAAGTTCCATCACTCTTTGTAGAATCAAGTGTGGATGACCGTCCAATGAAAACTGTTTCTCA
AGACACAAACATCCCAATCTACGCACAAATCTTTACTGACTCTATCGCAGAACAAGGTAAAGAAGGCGACAGCTACTACA
GCATGATGAAATACAACCTTGACAAGATTGCTGAAGGATTGGCAAAATAA

Protein sequence :
MKKLGTLLVLFLSAIILVACASGKKDTTSGQKLKVVATNSIIADITKNIAGDKIDLHSIVPIGQDPHEYEPLPEDVKKTS
EADLIFYNGINLETGGNAWFTKLVENAKKTENKDYFAVSDGVDVIYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSA
KDPNNKEFYEKNLKEYTDKLDKLDKESKNKFNKIPAEKKLIVTSEGAFKYFSKAYGVPSAYIWEINTEEEGTPEQIKTLV
EKLRQTKVPSLFVESSVDDRPMKTVSQDTNIPIYAQIFTDSIAEQGKEGDSYYSMMKYNLDKIAEGLAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF0577 NP_814342.1 adhesion lipoprotein Virulence Not named Protein 3e-111 78
ef0095 AAM75298.1 EF0095 Not tested Not named Protein 2e-111 78

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPH_1759 YP_001695035.1 manganese ABC transporter substrate-binding lipoprotein (adhesin B) (Saliva-binding protein) VFG1359 Protein 4e-139 99
SPH_1759 YP_001695035.1 manganese ABC transporter substrate-binding lipoprotein (adhesin B) (Saliva-binding protein) VFG2165 Protein 6e-87 58
SPH_1759 YP_001695035.1 manganese ABC transporter substrate-binding lipoprotein (adhesin B) (Saliva-binding protein) VFG2157 Protein 6e-82 53