Gene Information

Name : nadE (SPH_1550)
Accession : YP_001694854.1
Strain : Streptococcus pneumoniae Hungary19A-6
Genome accession: NC_010380
Putative virulence/resistance : Unknown
Product : NAD synthetase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0171
EC number : 6.3.1.5
Position : 1434581 - 1435405 bp
Length : 825 bp
Strand : -
Note : catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP; ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli

DNA sequence :
ATGAGTTTGCAAGAAACGATTATCCAAGAGCTGGGTGTCAAACCAGTGATTGATGCCCAGGAAGAAATCCGTCGTTCTAT
TGATTTCTTAAAAAGATATCTGAAAAAACATCCCTTCCTAAAAACCTTTGTACTAGGGATTTCTGGGGGACAAGACTCAA
CCTTGGCAGGACGTTTGGCGCAATTAGCTATGGAAGAACTGCGAGCTGAAACGGGAGACGATAGCTACAAATTTATCGCT
GTCCGCCTGCCATACGGAGTGCAAGCTGATGAAGCAGATGCTCAAAAAGCCCTAGCCTTCATCCAGCCAGATGTCAGCTT
GGTTGTGAATATCAAGGAATCAGTTGATGCCATGACAGCTGCAGTTGAAGCGACAGGTAGTCCTGTTTCAGACTTCAACA
AGGGGAATATCAAGGCACGTTGCCGTATGATTGCTCAGTATGCCCTTGCTGGTTCCCATAGCGGAGCGGTCATTGGAACA
GACCACGCCGCGGAAAATATCACAGGTTTCTTTACCAAGTTTGGTGACGGCGGTGCGGATATTCTCCCTCTTTACCGCCT
CAATAAACGCCAAGGAAAACAGCTCTTGCAGAAACTTGGCGCAGAGCCAGCCCTTTATGAAAAAATCCCAACGGCAGACC
TAGAAGAAGATAAACCAGGCCTAGCTGACGAAGTCGCACTTGGAGTCACCTACGCAGAGATTGACGACTACCTAGAAGGC
AAAACAATCAGCCCAGAAGCTCAAGCGACCATTGAAAACTGGTGGCACAAAGGCCAACACAAACGCCGCTTACCCATCAC
TGTATTTGATGACTTTTGGGAGTAA

Protein sequence :
MSLQETIIQELGVKPVIDAQEEIRRSIDFLKRYLKKHPFLKTFVLGISGGQDSTLAGRLAQLAMEELRAETGDDSYKFIA
VRLPYGVQADEADAQKALAFIQPDVSLVVNIKESVDAMTAAVEATGSPVSDFNKGNIKARCRMIAQYALAGSHSGAVIGT
DHAAENITGFFTKFGDGGADILPLYRLNKRQGKQLLQKLGAEPALYEKIPTADLEEDKPGLADEVALGVTYAEIDDYLEG
KTISPEAQATIENWWHKGQHKRRLPITVFDDFWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nadE YP_001800880.1 NAD synthetase Not tested Not named Protein 2e-63 58