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Name : SPH_1409 (SPH_1409) Accession : YP_001694718.1 Strain : Streptococcus pneumoniae Hungary19A-6 Genome accession: NC_010380 Putative virulence/resistance : Resistance Product : tetracycline resistance protein Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0480 EC number : - Position : 1306025 - 1307944 bp Length : 1920 bp Strand : - Note : identified by match to protein family HMM PF00009; match to protein family HMM PF00679; match to protein family HMM PF03144; match to protein family HMM PF03764; match to protein family HMM TIGR00231 DNA sequence : ATGAAAATTATTAATATTGGAGTTTTAGCTCATGTTGATGCAGGAAAAACTACCTTAACAGAAAGCTTATTATATAACAG TGGAGCGATTACAGAATTAGGAAGCGTGGACAAAGGTACAACGAGGACGGATAATACGCTTTTAGAACGTCAGAGAGGAA TTACAATTCAGACAGGAATAACCTCTTTTCAGTGGGAAAATACGAAGGTGAACATCATAGACACGCCAGGACATATGGAT TTCTTAGCAGAAGTATATCGTTCATTATCAGTTTTAGATGGGGCAATTCTACTGATTTCTGCAAAAGATGGCGTACAAGC ACAAACTCGTATATTATTTCATGCACTTAGGAAAATGGGGATTCCCACAATCTTTTTTATCAATAAGATTGACCAAAATG GAATTGATTTATCAACGGTTTATCAGGATATTAAAGAGAAACTTTCTGCCGAAATTGTAATCAAACAGAAGGTAGAACTG TATCCTAATATGTGTGTGACGAACTTTACCGAATCTGAACAATGGGATACGGTAATAGAGGGAAACGATGACCTTTTAGA GAAATATATGTCCGGTAAATCATTAGAAGCATTGGAACTCGAACAAGAGGAAAGCAAAAGATTTCAGAATTGTTCTCTGT TCCCTCTTTATCATGGAAGTGCAAAAAGTAATATAGGGATTGATAACCTTATAGAAGTTATTACGAATAAATTTTATTCA TCAACACATCGAGGTCAGTCTGAACTTTGCGGAAAAGTTTTCAAAATTGAGTATTCGGAAAAAAGACAGCGTCTTGCATA TATACGTCTTTATAGTGGCGTACTGCATTTGCGAGATTCGGTTAGAATATCGGAAAAGGAAAAAATAAAAATTACAGAAA TGTATACTTCAATAAATGGTGAATTATGTAAAATCGATAAGGCTTATTCCGGGGAAATTGTTATTTTGCAGAATGAGTTT TTGAAGTTAAATAGTGTTCTTGGAGATACAAAGCTATTGCCACAGAGAGAGAGAATTGAAAATCCCCTCCCTCTGCTGCA AACGACTGTTGAACCGAGCAAACCTCAACAAAGGGAAATGTTACTTGATGCACTTTTAGAAATCTCCGACAGTGACCCGC TTCTGCGATATTATGTGGATTCTGCGACACATGAAATCATACTTTCTTTCTTAGGGAAAGTACAAATGGAAGTGACTTGT GCTCTGCTGCAAGAAAAGTATCATGTGGAGATAGAAATAAAAGAGCCTACAGTCATTTATATGGAAAGACCGTTAAAAAA AGCAGAGTATACCATTCACATCGAAGTTCCACCGAATCCTTTCTGGGCTTCCATTGGTCTATCTGTAGCACCGCTTCCAT TAGGGAGCGGAGTACAGTATGAGAGCTCGGTTTCTCTTGGATACTTAAATCAATCGTTTCAAAATGCAGTTATGGAGGGG ATACGCTATGGCTGTGAACAAGGATTGTATGGTTGGAATGTGACGGACTGTAAAATCTGTTTTAAGTATGGCTTATACTA TAGCCCTGTTAGTACCCCAGCAGATTTTCGGATGCTTGCTCCTATTGTATTGGAACAAGTCTTAAAAAAAGCTGGAACAG AATTGTTAGAGCCATATCTTAGTTTTAAAATTTATGCGCCACAGGAATATCTTTCACGAGCATACAACGATGCTCCTAAA TATTGTGCGAACATCGTAGACACTCAATTGAAAAATAATGAGGTCATTCTTAGTGGAGAAATCCCTGCTCGGTGTATTCA AGAATATCGTAGTGATTTAACTTTCTTTACAAATGGACGTAGTGTTTGTTTAACAGAGTTAAAAGGGTACCATGTTACTA CCGGTGAACCTGTTTGCCAGCCCCGTCGTCCAAATAGTCGGATAGATAAAGTACGATATATGTTCAATAAAATAACTTAG Protein sequence : MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTDNTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMD FLAEVYRSLSVLDGAILLISAKDGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESKRFQNCSLFPLYHGSAKSNIGIDNLIEVITNKFYS STHRGQSELCGKVFKIEYSEKRQRLAYIRLYSGVLHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEF LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLRYYVDSATHEIILSFLGKVQMEVTC ALLQEKYHVEIEIKEPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVAPLPLGSGVQYESSVSLGYLNQSFQNAVMEG IRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPK YCANIVDTQLKNNEVILSGEIPARCIQEYRSDLTFFTNGRSVCLTELKGYHVTTGEPVCQPRRPNSRIDKVRYMFNKIT |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SSU05_0922 | YP_001198287.1 | translation elongation factor (GTPases) | Not tested | 89K | Protein | 0.0 | 96 |
| SSU98_0928 | YP_001200485.1 | translation elongation factor (GTPases) | Not tested | 89K | Protein | 0.0 | 96 |
| tetO | AFJ97266.1 | truncated tetracycline resistant protein | Not tested | Not named | Protein | 2e-164 | 75 |
| tet(W) | YP_005160006.1 | tetracycline resistance protein | Not tested | Not named | Protein | 0.0 | 69 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | X04388.gene.p01 | Protein | 0.0 | 98 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | M85225.gene.p01 | Protein | 0.0 | 97 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | NC_002758.1120355.p0 | Protein | 0.0 | 95 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | NC_009782.5559075.p0 | Protein | 0.0 | 95 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | AM180355.1.gene636.p | Protein | 0.0 | 93 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | L09756.gene.p01 | Protein | 0.0 | 79 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | AJ295238.gene.p01 | Protein | 0.0 | 72 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | AY485126.gene.p01 | Protein | 0.0 | 70 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | AJ222769.gene.p01 | Protein | 0.0 | 69 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | DQ294299.gene.p01 | Protein | 0.0 | 69 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | FN594949.1.gene24.p0 | Protein | 0.0 | 67 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | L42544.gene.p01 | Protein | 1e-126 | 44 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | AJ514254.gene.p01 | Protein | 3e-122 | 43 |
| SPH_1409 | YP_001694718.1 | tetracycline resistance protein | Z21523.gene.p01 | Protein | 2e-109 | 41 |
