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Name : SPH_1341 (SPH_1341) Accession : YP_001694658.1 Strain : Streptococcus pneumoniae Hungary19A-6 Genome accession: NC_010380 Putative virulence/resistance : Virulence Product : alkaline phosphatase synthesis transcriptional regulatory protein PhoP Function : - COG functional category : T : Signal transduction mechanisms COG ID : COG0745 EC number : - Position : 1242766 - 1243470 bp Length : 705 bp Strand : - Note : identified by match to protein family HMM PF00072; match to protein family HMM PF00486 DNA sequence : ATGAAAAAAATACTAATTGTAGATGATGAGAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA AGTTGTAACTGCTTTTAATGGTCGTGAAGCGCTAGAGCAATTTGAAGCAGAGCAACCAGATATTATTATTCTGGATTTGA TGCTTCCAGAAATTGATGGTTTAGAAGTTGCTAAGACCATTCGTAAGACAAGCAGTGTGCCCATTCTTATGCTTTCAGCC AAAGATAGTGAATTTGATAAGGTTATCGGTTTGGAACTTGGGGCAGATGACTATGTAACGAAACCCTTCTCCAATCGTGA GTTGCAGGCGCGTGTTAAAGCTCTTCTGCGTCGTTCTCAACCTATGCCAGTAGATGGTCAGGAAGCAGATAGTAAACCTC AACCTATCCAAATTGGGGATTTAGAAATTGTTCCAGACGCCTACGTGGCTAAAAAATATGGCGAAGAACTAGACTTAACC CATCGTGAATTTGAGCTTTTGTATCATTTAGCATCGCATACAGGTCAAGTCATCACGCGCGAACACTTGCTTGAGACTGT CTGGGGTTATGACTATTTTGGTGATGTCCGTACAGTTGATGTGACTGTACGACGTCTGCGTGAGAAGATTGAAGATACGC CCAGCCGACCAGAGTATATCTTGACGCGCCGTGGTGTAGGGTATTACATGAGAAATAATGCTTGA Protein sequence : MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPILMLSA KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRSQPMPVDGQEADSKPQPIQIGDLEIVPDAYVAKKYGEELDLT HREFELLYHLASHTGQVITREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPSRPEYILTRRGVGYYMRNNA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD42044.1 | hypothetical protein | Not tested | PAI II 536 | Protein | 2e-33 | 42 |
| c3565 | NP_755440.1 | response regulator | Not tested | PAI I CFT073 | Protein | 3e-33 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_012469.1.7685629. | Protein | 7e-101 | 100 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_002952.2859905.p0 | Protein | 8e-52 | 56 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_002745.1124361.p0 | Protein | 6e-52 | 56 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_009782.5559369.p0 | Protein | 6e-52 | 56 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_002951.3237708.p0 | Protein | 6e-52 | 56 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_002758.1121668.p0 | Protein | 6e-52 | 56 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_009641.5332272.p0 | Protein | 6e-52 | 56 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_013450.8614421.p0 | Protein | 6e-52 | 56 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_007622.3794472.p0 | Protein | 8e-52 | 56 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_007793.3914279.p0 | Protein | 6e-52 | 56 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_003923.1003749.p0 | Protein | 6e-52 | 56 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | HE999704.1.gene2815. | Protein | 8e-50 | 55 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_012469.1.7686381. | Protein | 2e-41 | 48 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | AE016830.1.gene1681. | Protein | 2e-44 | 47 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | FJ349556.1.orf0.gene | Protein | 4e-40 | 45 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | CP004022.1.gene3215. | Protein | 3e-33 | 44 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | CP001918.1.gene5135. | Protein | 1e-26 | 44 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | AM180355.1.gene1830. | Protein | 1e-36 | 43 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | CP001138.1.gene4273. | Protein | 6e-31 | 43 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | NC_002695.1.915041.p | Protein | 6e-31 | 43 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | CP000034.1.gene3834. | Protein | 6e-31 | 43 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | HE999704.1.gene1528. | Protein | 3e-32 | 42 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | AF162694.1.orf4.gene | Protein | 4e-33 | 42 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | AF155139.2.orf0.gene | Protein | 1e-37 | 42 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | DQ212986.1.gene4.p01 | Protein | 2e-35 | 42 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | AE000516.2.gene3505. | Protein | 5e-33 | 42 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | BAC0533 | Protein | 9e-31 | 42 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | CP000647.1.gene4257. | Protein | 9e-31 | 42 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | BAC0596 | Protein | 3e-27 | 41 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | CP001138.1.gene2239. | Protein | 3e-27 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | VFG1389 | Protein | 6e-31 | 45 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | VFG1563 | Protein | 9e-34 | 42 |
| SPH_1341 | YP_001694658.1 | alkaline phosphatase synthesis transcriptional regulatory protein PhoP | VFG1702 | Protein | 1e-33 | 42 |
