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Name : SPH_1300 (SPH_1300) Accession : YP_001694621.1 Strain : Streptococcus pneumoniae Hungary19A-6 Genome accession: NC_010380 Putative virulence/resistance : Unknown Product : ribonucleotide-diphosphate reductase subunit alpha Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0209 EC number : 1.17.4.1 Position : 1205288 - 1207447 bp Length : 2160 bp Strand : + Note : Catalyzes the rate-limiting step in dNTP synthesis DNA sequence : ATGGGATTAAAACATCTTGAAGACGTGACTTACTTCCGTCTCAATAACGAAATCAACCGTCCTGTCAATGGACAAATCAT GCTTCATAAAGATAAGGAAGCCTTGGATGCTTTCTTTAAAGAAAATGTAGTTCCAAACACTATGGTTTTTGATTCAATCA AAGATAAAATCAACTACCTCATTGAACACAACTACATAGAAACAGCCTTTATCAAGAAATACCGTCCAGAATTTTTGGAA GAATTGTCACAATTTATCAAAGACCAAAACTTCCAATTCAAGTCTTTCATGGCTGCTTATAAATTTTACAATCAATATGC CTTAAAGACTAATGACGGTGAATACTATCTTGAAAGTATGGAAGACCGTGTCTTCTTTAACGCCCTTTATTTCGCTGATG GGAATGAAGCTGTTGCAATCGATATTGCCAATGAAATCATCCACCAACGCTACCAACCTGCTACTCCTTCCTTCTTGAAT GCTGGACGTGCTCGTCGTGGGGAGTTGGTATCTTGTTTCTTAATCCAAGTGACGGATGACATGAACTCTATCGGACGTTC TATCAACTCTGCCCTTCAACTTTCACGTATTGGTGGTGGTGTGGGAATTACCCTCAGCAACCTTCGTGAAGCTGGTGCAC CTATCAAAGGCTATGAAGGAGCTGCTTCAGGTGTCGTACCAGTTATGAAACTCTTCGAAGATAGCTTCTCTTACTCAAAC CAATTGGGTCAACGTCAAGGTGCTGGGGTGGTTTACCTCAATGTCTTTCACCCAGATATCATTGCTTTCCTTTCAACTAA GAAAGAAAACGCTGATGAAAAAGTACGTGTCAAGACTCTATCACTTGGTGTTGTAGTACCTGATAAATTCTACGAATTGG CGCGTAAAAATGAAGAAATGTACCTCTTCAGCCCTTACTCTGTAGAAAAAGAATACAATGTGCCATTCAACTACATCGAT ATTACTGAAAAATACGATGAATTGGTCGCAAATCCAAATATTCGCAAGACAAAAATCAAGGCGCGTGATTTAGAAACTGA AATCTCTAAATTACAGCAAGAGTCTGGCTACCCTTATGTCGTCAACATTGATACGGCTAACCGTGCAAATCCTGTTGATG GAAAGATTATCATGAGTAACTTGTGTTCTGAGATTCTTCAAGTTCAAGAACCAAGCTTGATCAACGATGCTCAAGAATTC CTTCAAATGGGAACGGACGTTTCATGTAACCTTGGTTCAACCAACGTAGTCAACATGATGACTTCACCTGACTTTGGTCG TTCTATCCGTGCTATGGTTCGTGCCCTTACTTTCGTTACAGATAGTTCGCACATCGTAGCTGTTCCTACTATCGACCATG GAAATAGCCAAGCTCATACCTTTGGTCTTGGTGCCATGGGACTTCACAGCTACCTTGCCCAACAACTGATTGAATATGGT TCACCTGAGTCTGTTGAATTTACAAGCATCTACTTTATGCTTATGAACTACTGGACTTTGGTTGAGTCAAACAATATTGC GCGTGAACGTGGTATCACTTTCCACAATTTTGAAAAATCAGATTATGCTAAGGGAAGCTACTTTGACAAGTATGTAACTG GCGAATTTGTTCCAAAATCAGACCGTGTTAAAGAACTTTTCAAAGATGTCTTTATCCCAAGTGCTGCTGACTGGGCTGAA CTTCGAGACAAGGTTCAAGCAGATGGACTTTACCACCAAAACCGTCTAGCTGTTGCTCCAAATGGTTCGATCAGTTACAT CAATGACGTTTCTGCCTCTATCCACCCGATTACGCAACGTATCGAAGAACGTCAAGAAAAGAAAATCGGTAAAATCTACT ATCCTGCTGCTGGCTTGTCAACAGAAACCATTCCTTACTACACTTCTGCTTACGACATGGATATGCGTAAGGTGATTGAT GTTTACGCTGCTGCGACTGAGCACGTGGACCAAGGACTTTCACTCACACTCTTTATGCGTAGTGACATTCCAAAAGGACT TTACGAATGGAAGAGGGAAAATAAACAAACGACACGTGACTTGTCTATCCTTCGTAACTATGCCTTTAACAAGGGTATCA AGTCTATCTACTACGTCCGTACCTTTACAGATGATGGTGGAGAAGTCGGTGCCAACCAATGTGAAAGCTGTGTGATTTAG Protein sequence : MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDKEALDAFFKENVVPNTMVFDSIKDKINYLIEHNYIETAFIKKYRPEFLE ELSQFIKDQNFQFKSFMAAYKFYNQYALKTNDGEYYLESMEDRVFFNALYFADGNEAVAIDIANEIIHQRYQPATPSFLN AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSN QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGVVVPDKFYELARKNEEMYLFSPYSVEKEYNVPFNYID ITEKYDELVANPNIRKTKIKARDLETEISKLQQESGYPYVVNIDTANRANPVDGKIIMSNLCSEILQVQEPSLINDAQEF LQMGTDVSCNLGSTNVVNMMTSPDFGRSIRAMVRALTFVTDSSHIVAVPTIDHGNSQAHTFGLGAMGLHSYLAQQLIEYG SPESVEFTSIYFMLMNYWTLVESNNIARERGITFHNFEKSDYAKGSYFDKYVTGEFVPKSDRVKELFKDVFIPSAADWAE LRDKVQADGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVID VYAAATEHVDQGLSLTLFMRSDIPKGLYEWKRENKQTTRDLSILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cur_1481 | YP_001800875.1 | ribonucleotide-diphosphate reductase subunit alpha | Not tested | Not named | Protein | 3e-178 | 52 |
