Gene Information

Name : SPH_1246 (SPH_1246)
Accession : YP_001694571.1
Strain : Streptococcus pneumoniae Hungary19A-6
Genome accession: NC_010380
Putative virulence/resistance : Virulence
Product : hypothetical protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3451
EC number : -
Position : 1151177 - 1153492 bp
Length : 2316 bp
Strand : +
Note : -

DNA sequence :
ATGACTAATAAAAAAGAAGTAGTTAAAGGGAAAAAAGAGGAAGTGTTACCCTCTACGGCGAATACTCTTTATTATCAAGC
CCTGTATCAAAATGGTCTAATGCAGGTAAAAGAAGATTATTTCTCACAAAGCTACTTACTTGGTGATGTCAATTACCAAA
CTGTTGGTTTAGAAGATAAGGGCGCAATCATTGAGAAGTATTCTGATTTGATTAACTCCCTAGATGACCAAACCAACTTC
CAATTGACCATCTTTAATAAAAGATTGAATTTAGAAAAGTTTAGACAAAGTGTTTTGTATGAGGAAAAAGAAGATGGGTA
TGATAGCTATCGTAAAGAATTGAATCGGATGATGAATCAGAATTTAGACAGTGGTGAAAATAACTTTTCAGCTGTGAAAC
TGATTACCTTTGGTAGAAAGGATTCTAATCCCAAACAAGCCTATCGTTCCTTGTCCCAAATAGGAGAATATTTCAAGAGT
GGTTTCTCAGAAATTGATGCTCGCTTTGAATCCTTGGCTGGAGAAAACCGTGTGAACTTGTTGGCAGATATGCTTAGAGG
AGAACACCATCTTCCGTTTTCTTACCGTGATTTAACGAGATCGGGTCAGACAACTCGTCACTTTATAGCGCCTAATCTCT
TAGATTTCAAAAACAAGAATTACCTACAAATCAATGACCGCTTATTGCAGATTGTCTATGTGAGAGACTACGGCATGGAA
TTAGGGGATCAGTTTATTCGAGACCTCATGCAAGGAGATTTGGAATTGATTGTGAGCCTCCATGCTCAAAGTTCGACCAA
AGCAGATGCCATGAAGAAACTACGAACAAAGAAGACCTTGATGGAATCCCAAAAGATTGGGGAACAACAAAAACTAGCTC
GTACAGGTATCTATTTGGAAAAAGTAGGCCATGTTTTAGAAAGCAATATCGATGAAGCTGAGGAACTCTTAAAAACCATG
ACAGAGACAGGAGATAAACTGTTTCAAACAGTCTTTTTGATTGGTGTTTTTGGTCAGGATGAAGAAGAACTCAAACAAGC
TCTAGATACGATTCAACAAGTGGCCGGCTCAAATGACCTAATGATTGATAAACTTCCATATATGCAAGAAGCAGCCTTTA
ATAGTTTGCTGCCATTTGGTTGTGATTTTTTAGAGGGAGTATCACGGAGTTTATTAACATCTAATGTAGCAGTGAACTCT
CCATGGACTTCAGTAGATTTACAAGACCGTAGTGGGAAATATTACGGTATCAATCAAATATCAAGTAATATTATTACCAT
TGATCGCAGCCTATTAAATACACCATCTGGTCTAATTTTAGGGACATCTGGAGCCGGTAAAGGGATGGCAACCAAGCATG
AAATTATCACGACAAAAATCAAGGAATCTGGTGAAAATACAGAAATTATCATCGTGGATCCAGAAGCAGAATACAGTGTC
ATTGGACGAGCTTTTGGGGGAGAAATGATTGATATTGCGCCAGATTCCCAAACCTATCTCAATGTCCTTGACTTGTCTGA
AGAAAATATGGATGAAGATCCTGTAAAAGTAAAATCAGAATTTCTTTTATCCTTTATCGGCAAGTTATTGGATAGAAAAA
TGGATGGAAGAGAAAAATCGATTATTGACCGAGTTACCAGACTCACCTATCAGTCATTTAAAGAGCCTTCTTTGGAAGAA
TGGGTCTTTGTCTTGAGCCAACAACCAGAAGAAGAAGCGCAGAATTTGGCACTTGATATGGAACTGTATGTCGAAGGTTC
TCTTGATATTTTTTCTCATAAGACCAATATTCAGACAGGATCTAATTTCTTAATCTATAATGTTAAAAAGTTAGGAGATG
AGTTGAAACAAATTGCTCTTATGGTTGTTTTTGATCAGATATGGAATCGTGTCGTTCGGAATCAAAAATTAGGGAAGAAG
ACCTGGATTTATTTTGATGAAATGCAGCTTCTCTTATTAGATAAATATGCCAGTGATTTCTTCTTTAAATTGTGGAGTCG
TGTCAGAAAATATGGAGCCAGTCCGACTGGAATAACTCAAAATGTCGAAACCTTATTGTTAGATCCAAATGGTAGACGGA
TTATTGCCAATAGTGAATTTATGATTCTCCTCAAGCAAGCAAAAAATGACCGGGAAGAACTGGTTCAACTCTTAGGCTTG
TCAAAAGAACTCGAAAAATACCTAGTCAATCCAGAAAAAGGAGCAGGACTAATAAAAGCAGGTTCAGTTGTTGTTCCCTT
CAAAAATAAGATTCCTCAAGGTACTCAATTGTTTGATATTATGAGTACGGATCCTGATAAAATGGCTTCTAATTAA

Protein sequence :
MTNKKEVVKGKKEEVLPSTANTLYYQALYQNGLMQVKEDYFSQSYLLGDVNYQTVGLEDKGAIIEKYSDLINSLDDQTNF
QLTIFNKRLNLEKFRQSVLYEEKEDGYDSYRKELNRMMNQNLDSGENNFSAVKLITFGRKDSNPKQAYRSLSQIGEYFKS
GFSEIDARFESLAGENRVNLLADMLRGEHHLPFSYRDLTRSGQTTRHFIAPNLLDFKNKNYLQINDRLLQIVYVRDYGME
LGDQFIRDLMQGDLELIVSLHAQSSTKADAMKKLRTKKTLMESQKIGEQQKLARTGIYLEKVGHVLESNIDEAEELLKTM
TETGDKLFQTVFLIGVFGQDEEELKQALDTIQQVAGSNDLMIDKLPYMQEAAFNSLLPFGCDFLEGVSRSLLTSNVAVNS
PWTSVDLQDRSGKYYGINQISSNIITIDRSLLNTPSGLILGTSGAGKGMATKHEIITTKIKESGENTEIIIVDPEAEYSV
IGRAFGGEMIDIAPDSQTYLNVLDLSEENMDEDPVKVKSEFLLSFIGKLLDRKMDGREKSIIDRVTRLTYQSFKEPSLEE
WVFVLSQQPEEEAQNLALDMELYVEGSLDIFSHKTNIQTGSNFLIYNVKKLGDELKQIALMVVFDQIWNRVVRNQKLGKK
TWIYFDEMQLLLLDKYASDFFFKLWSRVRKYGASPTGITQNVETLLLDPNGRRIIANSEFMILLKQAKNDREELVQLLGL
SKELEKYLVNPEKGAGLIKAGSVVVPFKNKIPQGTQLFDIMSTDPDKMASN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
Spaf_1125 YP_006309927.1 hypothetical protein Not tested FWisland_1 Protein 0.0 99
SSU98_0982 YP_001200540.1 Type IV secretory pathway, VirB4 component Virulence 89K Protein 0.0 82
SSU05_0969 YP_001198335.1 Type IV secretory pathway, VirB4 component Virulence 89K Protein 0.0 82