Gene Information

Name : SPH_1137 (SPH_1137)
Accession : YP_001694478.1
Strain : Streptococcus pneumoniae Hungary19A-6
Genome accession: NC_010380
Putative virulence/resistance : Virulence
Product : ferric enterobactin transport ATP-binding protein FepC
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 1046622 - 1047416 bp
Length : 795 bp
Strand : +
Note : identified by match to protein family HMM PF00005

DNA sequence :
ATGAAAGGTCTGTGGTCAAATAATCTTACCTGCGGTTATGATGAAAAAATAATCTTGGAAAATATAAATATAAAAATACC
TGAAGAAAAAATATCAGTTATTATTGGGTCAAATGGTTGTGGGAAATCAACACTCATTAAAACCTTGTCTCGACTTATAA
AGCCATTAGAGGGAGAAGTATTGCTTGATAATAAATCAATTAATTCTTATAAAGAAAAAGATTTAGCAAAACACATAGCT
ATATTACCTCAATCTCCAATAATCCCTGAATCAATAACAGTAGCTGATCTTGTAAGCCGTGGTCGTTTCCCCTACAGAAA
GCCTTTTAAGAGTCTTGGAAAAGATGACCTTGAAATAATAAACAGATCAATGGTTAAGGCCAATGTTGAAGATCTAGCAA
ATAACCTAGTTGAAGAACTTTCTGGGGGTCAAAGGCAAAGAGTATGGATAGCTCTAGCCCTAGCCCAAGATACAAGTATC
CTACTTTTAGATGAGCCAACTACTTACTTGGATATCTCATATCAAATAGAACTATTAGACCTCTTGACTGATCTAAACCA
AAAATATAAGACAACCATTTGCATGATTTTGCACGATATAAATCTAACAGCAAGATACGCTGATTACCTATTTGCAATTA
AAGAAGGTAAACTTGTTGCAGAGGGAAAGCCTGAAGATATACTAAATGATAAACTAGTTAAATATATCTTTAATCTTGAA
GCAAAAATTATACGTGACCCTATTTCCAATTCGCCTCTAATGATTCCTATTGGCAAGCACCATGTTAACTCTTAA

Protein sequence :
MKGLWSNNLTCGYDEKIILENINIKIPEEKISVIIGSNGCGKSTLIKTLSRLIKPLEGEVLLDNKSINSYKEKDLAKHIA
ILPQSPIIPESITVADLVSRGRFPYRKPFKSLGKDDLEIINRSMVKANVEDLANNLVEELSGGQRQRVWIALALAQDTSI
LLLDEPTTYLDISYQIELLDLLTDLNQKYKTTICMILHDINLTARYADYLFAIKEGKLVAEGKPEDILNDKLVKYIFNLE
AKIIRDPISNSPLMIPIGKHHVNS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 3e-109 99
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 3e-109 99
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 6e-50 45
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 4e-46 42
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 4e-46 42
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 4e-46 42
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 4e-46 42
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 7e-43 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPH_1137 YP_001694478.1 ferric enterobactin transport ATP-binding protein FepC BAC0164 Protein 4e-43 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPH_1137 YP_001694478.1 ferric enterobactin transport ATP-binding protein FepC VFG0925 Protein 2e-56 48
SPH_1137 YP_001694478.1 ferric enterobactin transport ATP-binding protein FepC VFG1042 Protein 4e-43 41