Gene Information

Name : metB1 (OE2681F)
Accession : YP_001689174.1
Strain : Halobacterium salinarum R1
Genome accession: NC_010364
Putative virulence/resistance : Resistance
Product : cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 875184 - 876365 bp
Length : 1182 bp
Strand : +
Note : -

DNA sequence :
ATGAGCGGCAACGACGACGCCGATGACGCAGCCGACCGGTTCCAGACACGCGCGATCCACGCGGGCCAAGCGCCGGACTC
GGAGACGGGCGCGCTGATGACGCCGATCTTCGCGAACTCGACGTACGTCCAGGACGGCCCCGGCGATCACCGCGGCTACG
AGTACTCCCGGACGGGCAACCCGACGCGCACGGATCTGGAAGCCAACCTCGCGAGCCTGGAAGGCGGCGAGCACGGGCGC
GCGTTCGCCTCCGGAATGGCCGCGATCAACACCGTGTTGAACCTCCTGGCGGCCGGCGACCACGTGGTGGCGGGCGACGA
CGTGTACGGCGGCACCCACCGCATCTTCACGCAGGTCTACGAGGACTACGACATCGACTTCGACTTCGTCGACACCACCG
ACCACGACGCCGTCCGGGAGGCCATGGGGGAGGCGACGGAACTCCTCTGGGTGGAGACCCCGACGAACCCGTTGTTGAAC
GTCAACGACATCGGCGCGCTCGCGGACATCGCCCACGAGCACGACGCGCTGTGTGCGGTGGACAACACGTTCGCGACGCC
GTACCTCCAGCGCCCCCTGGAGTTCGGTGCCGACATCGTCTCGCACAGCCTCACGAAGTACCTCGGCGGGCACAGCGACC
TCGTTGCGGGCGCGCTGATCACCGACGACGACGACCTCGACGAGCAGTTCGGGTTCTACCAGAACTCCGTCGGCGCGACG
CCCAGTCCGTTCGACTGCTTCCTGGTGTTGCGCGGCACGAAAACCCTGGGCGTGCGCATGGACCGCCACTGTGAGACGGC
CATGGAGCTTGCGGCGTGGCTTGCGGATCACGAGCACGTCAGCCAGGTCCACTACCCGGGCCTGGAGAGCCACCCCGACC
ACGAGCTGGCCGCCGCGCAGATGGACGGCTTCGGCGGCATGGTCTCCTTCGAGTTGGACGCCACCCTCGAAGCGGCCAGC
GCGTTCGTCGAGGAGACCGACGTGTTCACGCTCGCGGAGTCACTGGGCGGCGTGGAGTCACTGATCGAGCAGCCCGCGGC
GATGACTCACGCCGCCATCCCGAAGGCCGAACGGGAGGCCGCGGGGCTCACCGACGGGCTGATCCGGGCGAGCATCGGCG
TCGAGCACGTCGACGACCTCAAGGCGGACCTCCAGCAGGCCATCGAGGCCGCCCTGCAGTAG

Protein sequence :
MSGNDDADDAADRFQTRAIHAGQAPDSETGALMTPIFANSTYVQDGPGDHRGYEYSRTGNPTRTDLEANLASLEGGEHGR
AFASGMAAINTVLNLLAAGDHVVAGDDVYGGTHRIFTQVYEDYDIDFDFVDTTDHDAVREAMGEATELLWVETPTNPLLN
VNDIGALADIAHEHDALCAVDNTFATPYLQRPLEFGADIVSHSLTKYLGGHSDLVAGALITDDDDLDEQFGFYQNSVGAT
PSPFDCFLVLRGTKTLGVRMDRHCETAMELAAWLADHEHVSQVHYPGLESHPDHELAAAQMDGFGGMVSFELDATLEAAS
AFVEETDVFTLAESLGGVESLIEQPAAMTHAAIPKAEREAAGLTDGLIRASIGVEHVDDLKADLQQAIEAALQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-87 51
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-88 51
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-62 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB1 YP_001689174.1 cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) BAC0207 Protein 1e-69 45