Gene Information

Name : metB2 (OE2173F)
Accession : YP_001688877.1
Strain : Halobacterium salinarum R1
Genome accession: NC_010364
Putative virulence/resistance : Resistance
Product : cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 590153 - 591370 bp
Length : 1218 bp
Strand : +
Note : -

DNA sequence :
ATGGACGACACACCTGCGTTCGAAACCCTCGCCGTCAGCCACGGCGAATCACCGCGCGAGACGCGCCACGGCGATGTCGT
CTCGCCCATCCACCTCGCCTCGACGTACGCCGTCCAGGAGTTGGACACCGACCTCAGCCTGGAGGGCGTCGACCCCGACG
ACGGGCAGTTCCTGTACTCGCGCCTCAACAATCCGACCAGACACGCCCTCGAACGGCGCCTCGCAGCCCTCGAAGGCGGC
GACCACGGCTTCGCGTTTGGCTCCGGCACCGCCGCCATCGCCACCGCCGCCTTCGCCGCCGTCGAACCCGGCGATCACGT
CGTCGCCTTCGACGACCTCTACGCCGGCACACGGCGCATGCTCGAAACCCTCTTCGAGGGGAACCTCGGTGTCGCCGTCT
CGTTCGTGGACGCCACCGACCCGGACGCCGTCGCCGACGCGATCCGTCCCGAAACCGCCTTCGTCTGGATGGAGACTCCC
ACAAACCCACGCATCAAGCTCTGTGACATCGCCGCCATCGCCGACATCACTGACGACGCCGGCGTCCTGTTCGGTGTCGA
CAACACCTTCCTCAGCCCCTACTTCCAACAGCCCCTGGCGCTCGGCGCGGACGTCGTTGCCCACTCCACGACGAAATACC
TCAACGGCCACAGCGACGCCGTCGGCGGCGCACTCGTCACCAACAACGACGCGCTCGCCGACAGCGTCGAGTTCCTCCAG
CAGGTCGGCCTCGGGAACATGCTCGCGCCGTTCGACGCCTACCTCGTGTTGCGCGGCATCAAAACCCTCGCCCCGCGGAT
GCGCGACCACGAGGCCAACGCCCTCGCCATCGCCGAATACCTCGCCGACCACGACCGCGTGACCGCGGTTCACTACCCCG
GCCTCGACTCCCACCCGCAACACGACCTCGCGGACGCCCAGCAGTCCGGCTACGGTGGCATCCTCTCGTTCGAACTCGAC
GGCGACCTCGCCGACGCCAAGCGCTTCCTCGACGCGCTCGACGAGTTCAACCTCGCGGTCAGCGTCGGCGGCGTCGAATC
ACTGGTGGAACTCCCCGCCGGCATGACCCACGAACCCATCCCGAAGCCCGACCGCGAAGCCATGGGCATCACGGACTCGC
TGATCCGCGTGTCCGTCGGCATCGAAGCCATCGAGGACCTCATCGCGGATCTCGACCGCGGCTTCGAGGCGGTCCGATCG
ACCACCCCGACAGCCTAA

Protein sequence :
MDDTPAFETLAVSHGESPRETRHGDVVSPIHLASTYAVQELDTDLSLEGVDPDDGQFLYSRLNNPTRHALERRLAALEGG
DHGFAFGSGTAAIATAAFAAVEPGDHVVAFDDLYAGTRRMLETLFEGNLGVAVSFVDATDPDAVADAIRPETAFVWMETP
TNPRIKLCDIAAIADITDDAGVLFGVDNTFLSPYFQQPLALGADVVAHSTTKYLNGHSDAVGGALVTNNDALADSVEFLQ
QVGLGNMLAPFDAYLVLRGIKTLAPRMRDHEANALAIAEYLADHDRVTAVHYPGLDSHPQHDLADAQQSGYGGILSFELD
GDLADAKRFLDALDEFNLAVSVGGVESLVELPAGMTHEPIPKPDREAMGITDSLIRVSVGIEAIEDLIADLDRGFEAVRS
TTPTA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-53 43
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 9e-55 43
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-45 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB2 YP_001688877.1 cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase) BAC0207 Protein 2e-51 41