Gene Information

Name : cadA (OE1245F)
Accession : YP_001688379.1
Strain : Halobacterium salinarum R1
Genome accession: NC_010364
Putative virulence/resistance : Resistance
Product : cadmium-transporting ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.1.-
Position : 120827 - 123037 bp
Length : 2211 bp
Strand : +
Note : -

DNA sequence :
ATGGACTGCTCGTCGTGCGCCGGCAGCGTCGCGGACGCCCTCGACGCCACCGCCGGCGTCACCGCCCACGAAGAACAGCC
GACGACGGGCTCCGTCGTCGTCACGCTCGACGAAAGCACGGCCACCACGCCGGACGTCGTGGCCGCCGTTGAGGCCGCCG
GCTACGACGTCACCGGAACCGACGGCGACCGAGACACCTCCCGGGCGGACGTCTGGACCAGCCCTCGCGCCCTCCAAACC
GCGGTCGGCGGCGTGTTCCTGCTCGCCGGACTGGCGTTGCGGTTCTTCGTCGGTGACGCGAACGTCGTGTTGGGGGTGGT
CGCCGGCACCAGCCTGCACGCCGCCGACGTCGCGTTCCTCGTCGCGGTCGCGGCCGGTGGCTTCAAGACGCTTCGCAACG
GCGCGCGCTCGGCCCGCGACCGCCGCATGGACATCGACTTCCTGATGTCGATCGCCATCCTCGGCGCGCTCACCGCCAGC
TTCGCGTTCGGGAAGCCGCTGTACTTCGAGGCCGCGACGCTCGCGGTCCTGTTCAGCATCGCGGAACTGCTTGAGGGGTA
CGCCATGGACCGCGCCCGCCAGTCGCTGCGCGAGCTCATGGCGCTGTCTCCCGATGAAGCGACGATCATCGACCCCGACG
GCACCGAGACGACGGTCCCGGCCGACACGGTTTCGATCGGCGACCGCGTTGCGGTGCGGCCGGGCGAAAAGATCCCGGCC
GACGGCGTCGTCGTTGACGGGGACAGCGCCGTCGACCAGTCGCCCGTGACGGGTGAATCCGTCCCCGAAAGCAAGCAGCC
GGGCGACGAGGTGTACGCCGGCACCGTCAACGAGACGGGGTATCTCGAAGTCGAGGTCACCGCCGCCCCGGGCGACGACA
CGCTGTCCCGCATCGTCGAACTCGTCGAGGACGCCCAGTCGAATCAGACCGACCGCGAGCAGTTCGTCGAACGCTTCGCC
GCCAAGTACACGCCTGCCGTCGTCGCGCTCGCGGTGCTCACGACGCTTGGATCGCCGTTCGTGCTCGGCGTGTCCTGGCC
GACTGCGGTCGTCCACGGGCTGACGCTGCTCGTGCTCGCGTGCCCGTGTGCGTTCGTCATCTCGACGCCGGTGTCAGTCG
TGTCGGCCATCACGAGCGCGGCCAACCACGGCGTGCTCGTCAAGGGCGGCACCCACCTCGAAGCCATGGCCGACGTCGAC
GTCGTCGCCTTCGATAAGACCGGCACGCTGACCGCGGGCGACCTTGCGGTCACCGACGTTCGCGGGCTCAACGGGCACCG
CGAGCGCGACGTGCTGGCGTGCGCTCGCGGCCTGGAAGCCCGCAGCGAACACCCCATCGCGGACGCCATCGTGGACGCCG
CCGACGAAGCCGGCGTCGACGCGCCGTCGGTCACGGACTTCGACAGCGTCACTGGCCAGGGGGTGCGCGCCACGCTCGAC
GGCCAACCGCATTTCGCCGGGAAGCCCGCGCTGTTCGAGGAACACGGCGTCGACCTGTCCCACGTGCATGCGACCACTGA
CGGCGGCCTGCGGGCGGCCCAGCCCGACTGCGAGCACGCCGACTGCCTGGATCTCCGGGCCGACACGATCCCCGACCTCC
AGGCCGCCGGCAAGACGGTGGTGTTGGTGGGCACCGCGGACGCGTTGCTCGGCGTGATCGCGGTCGGTGACACGGTGCGG
GCGGGCGCAGCCGACACCGTCTCCAGGCTCCGCGAGCACGGCGTCGCTCGGACCGTGATGCTGACCGGGGACAACGAGCG
CACCGCGCGCGCCGTCGGCGACGAGGTCGGCGTCGACGCGGTGTACGCCGACTGCCTCCCCGCGGAGAAAGCCAGCGTCG
TTGCGGACCTCCAGGACGAACACGGCGACGTGGCGATGGTCGGCGACGGCATCAACGACGCGCCCGCGCTGGCGGCTGCC
ACAGTCGGCATCGCCATGGGGGCGGCGGGCACCGACACCGCGATCGAGACGGCGGACGTGGCGCTGCTGGGGGACGCCAT
CACGACGCTACCGTACCTCTACGAGCTGGCCGGGGACACGAACACGGTCATCCGCCAGAACATCTGGGCGAGCCTCGGCC
TGAAAGCCGCGCTCGCGGTCGGGGTGCCGTTCGGCCTGGTGCCGATCTGGCTGGCGGTGCTCGCCGGCGACGCCGGCATG
ACGCTCGGGGTCACCGGCAACGCCCTCCGGCTGGGCCGCATCTCGCCGTAG

Protein sequence :
MDCSSCAGSVADALDATAGVTAHEEQPTTGSVVVTLDESTATTPDVVAAVEAAGYDVTGTDGDRDTSRADVWTSPRALQT
AVGGVFLLAGLALRFFVGDANVVLGVVAGTSLHAADVAFLVAVAAGGFKTLRNGARSARDRRMDIDFLMSIAILGALTAS
FAFGKPLYFEAATLAVLFSIAELLEGYAMDRARQSLRELMALSPDEATIIDPDGTETTVPADTVSIGDRVAVRPGEKIPA
DGVVVDGDSAVDQSPVTGESVPESKQPGDEVYAGTVNETGYLEVEVTAAPGDDTLSRIVELVEDAQSNQTDREQFVERFA
AKYTPAVVALAVLTTLGSPFVLGVSWPTAVVHGLTLLVLACPCAFVISTPVSVVSAITSAANHGVLVKGGTHLEAMADVD
VVAFDKTGTLTAGDLAVTDVRGLNGHRERDVLACARGLEARSEHPIADAIVDAADEAGVDAPSVTDFDSVTGQGVRATLD
GQPHFAGKPALFEEHGVDLSHVHATTDGGLRAAQPDCEHADCLDLRADTIPDLQAAGKTVVLVGTADALLGVIAVGDTVR
AGAADTVSRLREHGVARTVMLTGDNERTARAVGDEVGVDAVYADCLPAEKASVVADLQDEHGDVAMVGDGINDAPALAAA
TVGIAMGAAGTDTAIETADVALLGDAITTLPYLYELAGDTNTVIRQNIWASLGLKAALAVGVPFGLVPIWLAVLAGDAGM
TLGVTGNALRLGRISP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 8e-96 46
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 1e-97 43
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 1e-97 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_001688379.1 cadmium-transporting ATPase BAC0298 Protein 2e-79 44
cadA YP_001688379.1 cadmium-transporting ATPase BAC0100 Protein 1e-54 41