Gene Information

Name : thyA (Caul_3385)
Accession : YP_001685010.1
Strain : Caulobacter sp. K31
Genome accession: NC_010338
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 3657957 - 3658808 bp
Length : 852 bp
Strand : +
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGACGCTCATGAACGCCATCGCGCCCATCCACGCCGATCCCGTCGCCGCCGACCATCCCGAGCGGCAGTATCTCAACCT
GCTCGCCGACATCCTGGAGAACGGCGTCGAGCGCGGCGACCGCACGGGCACCGGCACCAAGGGCGTGTTCGGCCGGCAGA
TCCGCTTCGACCTGTCGCAAGGCTTCCCGGTGCTGACCACCAAGAAGCTGCACCTGCGCTCGATCATCGTCGAGCTGCTG
TGGTTCCTGCGCGGCGACACCAATGTGAAGTACCTGCAGGATAACGGCTGCAAGATCTGGGACGAGTGGGCCGACGAGAA
CGGCGACCTGGGTCCGGTCTATGGCAAGCAATGGCGCTCATGGGCGACCCCGAACGGGCAGTCGATCGACCAGATCCAAA
ATCTGATCGAAGGCCTGAAGACCAATCCCAACAGCCGCCGCCACATCGTCAGCGCCTGGAACCCGGCCGATGTCGAGGAC
ATGGCCCTGCCGCCCTGTCACTGCCTGTTCCAGTTCTTCGTGGCGGACGGCAAGCTCAGCTGCCAGCTCTACCAGCGCAG
CGCCGACGTCTTCCTGGGCGTGCCGTTCAACATCGCCTCCTACGCCCTGCTGACCCTGATGGTCGCCCAGGTGGTCGGCC
TGAAGCCGGGCGAGTTCGTCCACACCTTCGGCGACGCGCACCTCTACATGAACCACCTGGACCAGGCCCGCGAGCAGTTG
CAACGCGAGCCCAAACCCTTCCCCACCCTGAAGATGGCCAACAAGCGCGACCTATTCGCTTTCGAGTACGCCGACTTCCA
GCTGGAGGGCTACGAGGCCCACCCGCACATCAAGGCGGCGGTCGCCGTTTGA

Protein sequence :
MTLMNAIAPIHADPVAADHPERQYLNLLADILENGVERGDRTGTGTKGVFGRQIRFDLSQGFPVLTTKKLHLRSIIVELL
WFLRGDTNVKYLQDNGCKIWDEWADENGDLGPVYGKQWRSWATPNGQSIDQIQNLIEGLKTNPNSRRHIVSAWNPADVED
MALPPCHCLFQFFVADGKLSCQLYQRSADVFLGVPFNIASYALLTLMVAQVVGLKPGEFVHTFGDAHLYMNHLDQAREQL
QREPKPFPTLKMANKRDLFAFEYADFQLEGYEAHPHIKAAVAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 5e-83 60