Gene Information

Name : guaA (Caul_2216)
Accession : YP_001683842.1
Strain : Caulobacter sp. K31
Genome accession: NC_010338
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 2412657 - 2414243 bp
Length : 1587 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGAACGACGCTGAAAAGGACCCGCGCATGATCACCGAAACCCACCACCAGCGCGTCCTGATCGTCGATTTCGGCAGCCA
GGTGACCCAGCTGATCGCCCGCCGGGTGCGCGAGGCGGGGGTCTATTGCGAGATCCACCCGTTCGACAAGGCCGAGGCCA
TGGTCGACGACTACGCCCCGTCGGCGATCATCCTGTCGGGCGGTCCAGCCAGCGTGCTGGAGGCCGACAGCCCCCGCATC
GGCAAGAAGCTATTCGAGTTGGGCGTGCCGCTGCTGGCCGTCTGCTATGGCCAGCAGCTGCTGTGCGACCTGTTGGGCGG
CCAGGTGGAGGGCGGTCATGCCGGCGAGTTCGGGCGCGCCGAGCTGACCATCGGCAAGGCCAGCCCGCTGTTCGAAGGTC
TGGCGGACGTTGGCGGCCTGGAAACCGTGTGGATGAGTCACGGCGACCGGGTCACCGCGATCCCGGAAGGCTTCGAGGTG
ATCGCTACCTCGGTGGGCGCCCCGTTCGCGGCCATCGCCGACGATGCCCGCAAGATCTACGGCGTGCAGTTCCATCCCGA
GGTCGTCCACACGATCAACGGCGCTCAAATCTACCGCAACTTCCTGAAGCTCGCCGGCCTGAAGGGCGACTGGACCATGG
CGGCCTTCCGCCAGGAGATGGTCCAGAAGATCCGCGACCAGGTCGGGACCGGCAAGGTGATCTGCGGTCTGTCGGGCGGG
GTCGACAGCTCGGTGGCCGCCGTGCTGATCCACGAGGCGATCGGTGACCAACTGACGTGCGTGTTCGTCGACACCGGTCT
GCTGCGCCTGAACGAGGCCGATCAGGTCGTCACCCTGTTCCGCGACCACTACAACATCCCGCTGATCCATGTGGACGCCG
GCGCGGAATTCCTGGGCGCGTTGGCCGGCGTCAGCGATCCCGAGACCAAGCGCAAGATCATCGGCGGCAAGTTCATCGAC
ATCTTCGACCGCGAGGCGGCCAAGATCGACGGCGCGGACTTCCTGGCCCAGGGCACCCTCTACCCCGACGTGGTCGAGAG
CGTCTCGGCCCGCGGCGGCCCCTCGGCGGTGATCAAGAGCCACCACAATGTGGGCGGTCTGCCGGACTTCATGAAGCTGA
AGCTGGTCGAACCGCTGCGCGAGCTGTTCAAGGACGAGGTCCGCGCCTTGGGCGTCGAGCTGGGTCTGGCCCCGGCCTTC
GTCGGCCGCCACCCGTTCCCAGGTCCGGGCCTGGCCATCCGCATCCCGGGCGACATCACGCCCGAGAAGGTCGACGTGCT
GCAACAGGCCGACGCGATCTATCTGGACGAGATCCGCAAGGCTGGACTCTACGACAAGATCTGGCAGGCCTTCGCCGTCC
TCCTTCCCGTGAAGACGGTCGGCGTGATGGGCGACGCCCGCACCTATGAGAACGTCCTGGCCCTGCGCGCCGTCACCTCG
ACCGACGGCATGACCGCCGACTTCTTCGAGTTCCCCTGGGACGTGCTGGGCAAGACCGCCACCCGGATCATCAACGAGGT
CCGAGGCGTCAATCGAGTCGTCTACGACGTGACGTCCAAACCGCCTGGGACCATCGAATGGGAATGA

Protein sequence :
MNDAEKDPRMITETHHQRVLIVDFGSQVTQLIARRVREAGVYCEIHPFDKAEAMVDDYAPSAIILSGGPASVLEADSPRI
GKKLFELGVPLLAVCYGQQLLCDLLGGQVEGGHAGEFGRAELTIGKASPLFEGLADVGGLETVWMSHGDRVTAIPEGFEV
IATSVGAPFAAIADDARKIYGVQFHPEVVHTINGAQIYRNFLKLAGLKGDWTMAAFRQEMVQKIRDQVGTGKVICGLSGG
VDSSVAAVLIHEAIGDQLTCVFVDTGLLRLNEADQVVTLFRDHYNIPLIHVDAGAEFLGALAGVSDPETKRKIIGGKFID
IFDREAAKIDGADFLAQGTLYPDVVESVSARGGPSAVIKSHHNVGGLPDFMKLKLVEPLRELFKDEVRALGVELGLAPAF
VGRHPFPGPGLAIRIPGDITPEKVDVLQQADAIYLDEIRKAGLYDKIWQAFAVLLPVKTVGVMGDARTYENVLALRAVTS
TDGMTADFFEFPWDVLGKTATRIINEVRGVNRVVYDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-131 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-131 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-131 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-117 52