Gene Information

Name : pykA (HM1_0076)
Accession : YP_001678712.1
Strain : Heliobacterium modesticaldum Ice1
Genome accession: NC_010337
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 65427 - 67217 bp
Length : 1791 bp
Strand : -
Note : -

DNA sequence :
ATGCATGCCTATATCCAAAAGGCTTCTCTGTCCGGAACGCCCCGCACGAAGATCGTCTGCACCGTCGGACCGGCTAGTTC
TGACCCTACCATCCTGATGGAGATGATTCGGGCCGGCATGCGGGTGGCCCGGCTGAACTTTTCCCACGGCACCTACGAGG
AGCATGCCGCCCGCATCGCTGCCGTTCGCCAGGCGGCCGATGCCTTAGGGCAGCCCATCGCCATCCTCCTCGACACGAAA
GGCCCGGAGATCCGCCTCGGCCAAGTGTCCGGCGGCAAAATCACCCTTGACGAAGGCGCGGAAGTGACCCTCTTCCCTGA
CGATGGGACCTTGGGGACGAAGGAGCGCCTGCCTATCAGCTACGCCGGGCTCGTTGAAGATGTCCGGCCCGGCGTACGGG
TGCTTATCGACGACGGGAACATCGAGATGGAAGTGACGGCTGTGGAGGCCGGTGAGATCCGCTGCCGCATCAAAAACGGC
GGCGATGTGAGCAGCCGCAAGGGTGTCAGCGTCCCCGGCGTGGCCTTGCGCATGCCGGCCATCAGCGAAAAGGAAGTGAA
GGATCTCGAGTTCGGCATCGCCCAGGACATGGATTTTGTCGCCATCTCCTTTGTCCGCGACGCCTCTGATGTGCTCGGCA
TCCGCAAGATCCTGGAAGACCGCGGCGCCTCCATGCAGCTGATCGCCAAGATCGAGAACCACCAGGGCGTTGACAACATC
GACGAGATCCTGGCCGTCTCTGACGGGATCATGGTCGCCCGGGGCGATCTCGGGGTGGCCATCCCGACGGAAGACGTCCC
TCTGGTGCAGAAGATGATCATCGAAAAGTGCAACATCGCCGGCAAGCCGGTGATCACGGCGACCCAGATGCTCGATTCAA
TGATCCGCAACCCTCGGCCCACCCGGGCCGAAGCGACGGACGTGGCCAACGCCATCTTGGATGGAACCGATGCCATCATG
CTCTCCGGCGAGACGGCAGCCGGTAAGTACCCTGTCGAGGCCGTCACGATGATGGCCCGCATCGCCATACGTACCGAACA
AGCCCTCCGCCACGATGAGGAACTGGATCGCCGCCGCAAAGCCGGCCTTGGCTCGGTCACCGATTCGATCAGCCATGCTA
CCTGCAGCATCGCGGCCGACTTGAAGGCAAAGGCGATCATCACCCTCACGAAAGCCGGCTCGACGGCTCGCATGGTCTCC
CGCTACCGCCCTGATTGCCCTATCATCGCCGCGACGCCGGAGACAAAAGTGATGCGTCAGATGGCCGTCGTCTGGGGCGC
CGAGCCGATGAAGGTGCGGGAGACGGCGGGGACGGACGAGATGCTCGGCGACGCTATCGACTGCGCTCTGAAGGAAGGCC
GTATCGAGTCAGGCGACCTCGTCGTCGTCACGGCCGGCGTCCCTGTCGGCGTATCCGGAACGACCAACCTGCTCAAGGTT
CATGTGGCCGGTCGGGTGCTGGCCCACGGCATGGGCATCAGCCGCAAGAAAGCAGTCGGCAAGGTGCGCCTCTGCCGATC
CGCCGCCGACGCCGCGCGGCTGGAGCGGGGCGAGATCCTCGTCGCCTACGGCACTGATCGAGATTACGTGCCGGCCCTTG
AACGCTGCGCCGGCATCATCACCGTGGAAGGCGGCCTCACCTCCCACGCGGCTATCGTAGGGCTGCAGTTCGGTATCCCC
GTCATCGTCGGCGTCGACAACGCCTTCGAGGTCCTTCCCGACGGCGCCGTGGTCACCATCGACGCCACCGAGCGAGGGAT
GATCTACGAGGGAACAGCGCGGGTTTTGTAA

Protein sequence :
MHAYIQKASLSGTPRTKIVCTVGPASSDPTILMEMIRAGMRVARLNFSHGTYEEHAARIAAVRQAADALGQPIAILLDTK
GPEIRLGQVSGGKITLDEGAEVTLFPDDGTLGTKERLPISYAGLVEDVRPGVRVLIDDGNIEMEVTAVEAGEIRCRIKNG
GDVSSRKGVSVPGVALRMPAISEKEVKDLEFGIAQDMDFVAISFVRDASDVLGIRKILEDRGASMQLIAKIENHQGVDNI
DEILAVSDGIMVARGDLGVAIPTEDVPLVQKMIIEKCNIAGKPVITATQMLDSMIRNPRPTRAEATDVANAILDGTDAIM
LSGETAAGKYPVEAVTMMARIAIRTEQALRHDEELDRRRKAGLGSVTDSISHATCSIAADLKAKAIITLTKAGSTARMVS
RYRPDCPIIAATPETKVMRQMAVVWGAEPMKVRETAGTDEMLGDAIDCALKEGRIESGDLVVVTAGVPVGVSGTTNLLKV
HVAGRVLAHGMGISRKKAVGKVRLCRSAADAARLERGEILVAYGTDRDYVPALERCAGIITVEGGLTSHAAIVGLQFGIP
VIVGVDNAFEVLPDGAVVTIDATERGMIYEGTARVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 8e-90 49
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-91 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-90 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-90 49
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 9e-55 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_001678712.1 pyruvate kinase VFG0479 Protein 7e-91 49