Gene Information

Name : guaA (HM1_0057)
Accession : YP_001678693.1
Strain : Heliobacterium modesticaldum Ice1
Genome accession: NC_010337
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 46895 - 48436 bp
Length : 1542 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
TTGGCTAAGCCCCATGAAACCATCTTGGTCCTCGACTTCGGCGGTCAATATAACCAACTGATCGCGCGCCGCGTCCGAGA
ACTGCACGTCTACTGCGAGATGCACCCCTACACGATCAGCGTCGACGCCATCCGGGAGATGAATCCCAAGGGCATCATCT
TCACCGGCGGTCCGGCCAGCGTCTATGAAGAAAAAGCGCCTGCCGTCGACCCGGCCATCTACGACCTGGGCATCCCTATC
CTGGGCATCTGCTACGGCATGCAACTCATGGTCAACCAACTGGGAGGCAAGGTCGGCAGGGCCGAATCGCGCGAATACGG
CAAGGCGTCCCTCACCATCACCGCTTCTGAAGGCCCCTTCGCCGGCATGGAAGGCGATGTGCAGTGCTGGATGAGCCATG
GCGACAAAGTAGAAGTCCTGCCCCACGGCTTCGTCGGCTCCGGCAAAACAGACCATGCCCCCTTTGCGGCCATGGCCGAT
CCGGTGCGCCGCTTCTACGGTGTCCAGTTCCACCCCGAGGTGCGCCACACGCCCCAAGGCATGGACATGATGCGCAACTT
CCTCTTCGGCGTCTGTGGCTGCACCGGTGAGTGGACCATGGAAAACTTCATCGAAGAACAGGTCGCGGCCATCCGCGCCC
GCGTCGGCAGCGGCAAAGTCCTCTGCGCCCTCTCGGGCGGCGTCGACTCCTCCGTGGCGGCCCTCCTCGTCCACCGCGCT
GTCGGCGAGCAGCTGACCTGTGTCTACGTCGATCACGGCTTCATGCGCCTCAACGAATCGGAGCGGATCATCAAGACCTT
CCGCGACGAACTGGGCATGAACCTGATCGCCGTCGAAGCGTCAGAACGCTTCATGGCCAAGGTTGCCGGTGTCTCCGACC
CGGAGACGAAGCGCAAAAGCATCGGCAACGAATTCATCCGCGTCTTCGAAGAGGAAGCGGCCAAATTGGGCCAGGTGGAC
TTCCTGGTGCAAGGCACCCTTTACCCCGACGTCGTCGAGAGCGGTACCTCGACAGCCGAGACGATCAAGACCCACCACAA
CGTGGGCGGCCTGCCCGAAGACATGAAATTCGAACTGATCGAACCCCTGCGCACCCTCTTTAAGGACGAGGTGCGGGAAG
TGGGCCAGAGACTGGGCCTGCCTGAAGATATCGTCTGGCGCCAGCCCTTCCCCGGACCGGGTCTGGCCATCCGCGTCCTC
GGCGAGATCACCAAGGAGAGCCTGGACATCCTGCGTCACGCTGATGACATTGTCTTCCAAGAGATCAAAAAAGCCGGTCT
TTACCGGCAGATCTGGCAGTCCTTTGTCGTGCTGCCGACAACCGTCCGCAGCGTCGGCGTCATGGGCGACGGCCGCACCT
ACGAGTACCCGGCCATCCTGCGGGCCGTCACCTCTGACGACGCCATGACGGCCGACTGGGCACGGCTGCCCTACGAGTTG
CTGGAGAAGATCTCCAACCGGATCGTCAACGAGGTCAAAGGCGTCAACCGCGTCGTCTACGACATCACGTCGAAGCCGCC
GGGGACGATTGAATGGGAATAA

Protein sequence :
MAKPHETILVLDFGGQYNQLIARRVRELHVYCEMHPYTISVDAIREMNPKGIIFTGGPASVYEEKAPAVDPAIYDLGIPI
LGICYGMQLMVNQLGGKVGRAESREYGKASLTITASEGPFAGMEGDVQCWMSHGDKVEVLPHGFVGSGKTDHAPFAAMAD
PVRRFYGVQFHPEVRHTPQGMDMMRNFLFGVCGCTGEWTMENFIEEQVAAIRARVGSGKVLCALSGGVDSSVAALLVHRA
VGEQLTCVYVDHGFMRLNESERIIKTFRDELGMNLIAVEASERFMAKVAGVSDPETKRKSIGNEFIRVFEEEAAKLGQVD
FLVQGTLYPDVVESGTSTAETIKTHHNVGGLPEDMKFELIEPLRTLFKDEVREVGQRLGLPEDIVWRQPFPGPGLAIRVL
GEITKESLDILRHADDIVFQEIKKAGLYRQIWQSFVVLPTTVRSVGVMGDGRTYEYPAILRAVTSDDAMTADWARLPYEL
LEKISNRIVNEVKGVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-161 62
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-162 62
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-162 62
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-145 55