Gene Information

Name : hsdR (HM1_3070)
Accession : YP_001681587.1
Strain : Heliobacterium modesticaldum Ice1
Genome accession: NC_010337
Putative virulence/resistance : Unknown
Product : type i site-specific deoxyribonuclease, hsdr family
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0610
EC number : -
Position : 3016919 - 3020122 bp
Length : 3204 bp
Strand : -
Note : -

DNA sequence :
ATGTCGCAACACCAGGCGTTCTGCGAATCGGAACTGGAAGAGGCCGCCCTGGAATGGTTTCAGGAACTGAACTATGAAAC
CGCCTTCGCCCCCGAACTCTCGCCGGGCGGCGATTACCCGGAACGGGAAGACTATGGCGACGTCATCCTCCAGGATCGGT
TGCGAGACGCGCTCCAGCGGATCAACCCGCACCTGCCTCCCGAAGCCATCGAGGACGCCTACCGGCAGATCGCCATCCCC
CAGAGCCCGAGCCTGCTCATGAACAACAAGGCCTTCCACAAGCTGATCACCGACGGGATCGACATAAGTTACCGCCACAA
AGGCGGCGCTGTCCGCTATGCAAAAGCCATGGTCTTCGATTTTGACCCCTGCCGTGTTGATAATAACGACTGGCTCGTCG
TCAACCAGTTCACCGTCATCGAAAACCGGGTGGAGAAACGGCCCGACATGGTCGTCTTCGTCAACGGCATCCCCCTCGTC
GTCATCGAACTGAAGAGCAGTTCCGATGAAGAGGTCGGCATCAGCGAAGGCTTCAACCAACTACAGACCTACAAGCAGAC
CATCCCCTCGCTCTTTACATATAACGCCTTCATGGTGACGAGCGACGGGATCAACGCCAGGGCAGGGACGCTGACGGCTG
ATGAAGACCGCTTCATGATGTGGCGGACCATCGACGGCGACGATGTGGCGCCATTGTCGATCCCCCAACTGGAAGTCCTA
ATTAAAGGCATGTTCGACAAGCGCCGGCTCCTCGACATCGTCAGGCACTTCATCACCTTCCAGACCGATGGCCGCGATAC
CTACAAGCTCCTGGCGGGCTATCACCAGTACCATGCCGTCAACAAAGCCGTCGACAGCACCGTCCGGGCGACGTTAGAAA
AGGGCGACCGTCGGATTGGCGTCATATGGCACACGCAAGGTTCCGGCAAGAGTCTTTCCATGGTCTTTTACACCGGTAAA
TTGGTTCTGGCAGAGGAGTTGGACAATCCGACCATCGTCGTCATCACTGACCGCAATGATTTAGACGATCAACTCTTCGG
CGCCTTCGCCCGTTCAAAAGACCTGCTTCGGCAGACGCCGGTGCAAGCGAAAGACCGGGCCGATCTGCGCCGCCTCTTGG
AGCGGGAGGCCGGCGGGATCATCTTCACCACCATCCACAAATTCGCCCCCGAAGCCAAGGGTGATCGCATCCCCGTGTTG
ACAGACCGAAAAAATGTCATCGTCATCGCCGACGAGGCCCACCGCAGCCAGTACGGCTTCGGCGCCGATGTGGTGGAAGG
AAAAGACGAAGCGGACATCAAATACGGCTACGCCAAATATATGCGCGACGCCCTGCCCAACGCCTCCTACATCGGCTTTA
CCGGCACGCCCATCGAACTGACCGATAAGAACACCCGCGCCGTCTTCGGCGATTACATCGACATCTATGACATGACCCGC
GCCGTTGAAGACGGCACCACCGTCAAGATCTACTACGAGAGCCGCATCGCCAAGCTCGACCTGCCCGACGAGATGAAGCC
CGTCGTCGATGAGGAATACGAAGAGATCACCGAACATCAGGAATACGAGCAAAAAGAAAAGCTGAAGTCCAAGTGGTCCC
GCCTGGAAGCCATCGTCGGCGCCGACGAGCGGATCCAGGTGGTGGCCCGAGACATCGTCGAGCACTTCGAGAAACGTCAG
GCCGCCCAGGAGACCGCCGTCGGCAAAGCCATGATCGTCGTCATGTCCCGGCGCATCGCCGTCGACCTGTATCATGCCAT
CGTCACCCTCCGTCCCGAATGGCACAGCGATGATCTAGACAGAGGCGTCATCAAGGTGGTCATGACGGGGGGCTCCGCCG
ACCCGAAGGAATGGCAGCCCTTCATCGGTACGAAGGCCACTCGTGATCGCCTCGCCAAGCGCATGAAAGACAACGATGAT
GAACTGAAACTGGTCATCGTCCGCGACATGTGGCTCACCGGCTTCGACGTGCCCAGCATGCACACCATGTACATCGATAA
GCCTATGGGCGGCCACAACCTGATGCAGGCCATAGCTAGGGTCAACCGCGTCTTTCGGGAAAAGCAGGGCGGCTTAGTCG
TCGACTACATCGGCATCGCTGAGAACCTGAAAGCCGCCTTGCGAGATTACACGGAAAGCGACAAGCAGACGACCGGCGTC
GACACGGACCAGGCGGCGGAGGTCATGCTGGAGAAGTATGACCTGATCCAAGAGATGCTTCACGGCCACGACTACAGCAA
GTTTTTCACAGGCAAAGCCAGCGACCGCATGCAGGCCATCGTCGAAACGATCGACTTCGTCATCGGGCTCCGTGAGCGCA
AAGATGAATACATGCGCCTCGTCACGGAACTGTCCAAGGCCTACTCCCTCTGCGCCACCACCGACGCGGCAGAAAAGCTC
AACTTGGAAGTGGGCTTCCACAAGGCCGTCAAAGCGGGCATCATCAAGATGATCCCGGAGAACACAAAAAAGAGAACAGG
CGCCCACTTGGACGCCCAGTTAAACCAGTTGATCTCCAAGTCGATCTCCTCGAACGAGGTCATCGACATCCTGCAGGCCG
TAGGCCTGCAAAAGCCCAACATCGCCATCCTGTCCGATGAGTTCCTTGAAGAAGTGCGGGTGATGAAGCAGAAAAACCTG
GCTGTCGAACTACTCAACCGCCTGCTCAAAGGCAAGGTCAAAGCCTTCGCTCGCAAGAACCTGATCCTTTCTAAAAAGTT
TTCCGAAATGCTGGAACAGGCCATCAAGAAGTACCAGAACCGTACCATTGAGACGACCCAGGTGATCATCGAACTGATCG
AACTGGCCAAAGAAGTGAACAAGGCTCATGGCCGGGGTGAAAACACGGGCCTGACCGAAGACGAATTGGCCTTCTATGAC
GCCTTAGCCGACAATGAATCGGCGAGAGAACTCATGGGCGACGAGATCCTCAAACAAATCGCCAGGGATCTGACCCAGCA
GATCAAGCGGAACATGACCGTCGACTGGAGCCTGAGAAGCAGCGTCCAGGCAAGAATGAAGATGATCATCAAGCGGCTGT
TGAAGAAATACAACTACCCCCCGGACAATCGCGAGAAAGCCCTGTCCACCGTCATGGAACAGGCGCGGTTGCTCTGTGTC
AGCGAGGCAGCAGCCCTGAACAGCGGCGACCAGGTTTCCGAACTGAGAGTAGCGGAAAGACTGGATCATCGCTACGAGGT
CTAA

Protein sequence :
MSQHQAFCESELEEAALEWFQELNYETAFAPELSPGGDYPEREDYGDVILQDRLRDALQRINPHLPPEAIEDAYRQIAIP
QSPSLLMNNKAFHKLITDGIDISYRHKGGAVRYAKAMVFDFDPCRVDNNDWLVVNQFTVIENRVEKRPDMVVFVNGIPLV
VIELKSSSDEEVGISEGFNQLQTYKQTIPSLFTYNAFMVTSDGINARAGTLTADEDRFMMWRTIDGDDVAPLSIPQLEVL
IKGMFDKRRLLDIVRHFITFQTDGRDTYKLLAGYHQYHAVNKAVDSTVRATLEKGDRRIGVIWHTQGSGKSLSMVFYTGK
LVLAEELDNPTIVVITDRNDLDDQLFGAFARSKDLLRQTPVQAKDRADLRRLLEREAGGIIFTTIHKFAPEAKGDRIPVL
TDRKNVIVIADEAHRSQYGFGADVVEGKDEADIKYGYAKYMRDALPNASYIGFTGTPIELTDKNTRAVFGDYIDIYDMTR
AVEDGTTVKIYYESRIAKLDLPDEMKPVVDEEYEEITEHQEYEQKEKLKSKWSRLEAIVGADERIQVVARDIVEHFEKRQ
AAQETAVGKAMIVVMSRRIAVDLYHAIVTLRPEWHSDDLDRGVIKVVMTGGSADPKEWQPFIGTKATRDRLAKRMKDNDD
ELKLVIVRDMWLTGFDVPSMHTMYIDKPMGGHNLMQAIARVNRVFREKQGGLVVDYIGIAENLKAALRDYTESDKQTTGV
DTDQAAEVMLEKYDLIQEMLHGHDYSKFFTGKASDRMQAIVETIDFVIGLRERKDEYMRLVTELSKAYSLCATTDAAEKL
NLEVGFHKAVKAGIIKMIPENTKKRTGAHLDAQLNQLISKSISSNEVIDILQAVGLQKPNIAILSDEFLEEVRVMKQKNL
AVELLNRLLKGKVKAFARKNLILSKKFSEMLEQAIKKYQNRTIETTQVIIELIELAKEVNKAHGRGENTGLTEDELAFYD
ALADNESARELMGDEILKQIARDLTQQIKRNMTVDWSLRSSVQARMKMIIKRLLKKYNYPPDNREKALSTVMEQARLLCV
SEAAALNSGDQVSELRVAERLDHRYEV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hsdR BAH57699.1 type I restriction-modification system endonuclease homologue Not tested Type-VII SCCmec Protein 0.0 56
hsdR BAD24840.1 type I restriction-modification system endonuclease homologue Not tested Type-V SCCmec Protein 0.0 55
hsdR YP_251977.1 type I restriction-modification system restriction subunit Not tested SCCmec Protein 0.0 55
api52 CAF28526.1 hsdr-like Type I restriction enzyme Not tested YAPI Protein 0.0 49