Gene Information

Name : cadA (HM1_2793)
Accession : YP_001681332.1
Strain : Heliobacterium modesticaldum Ice1
Genome accession: NC_010337
Putative virulence/resistance : Resistance
Product : cadmium-translocating p-type ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : -
Position : 2762403 - 2764757 bp
Length : 2355 bp
Strand : +
Note : -

DNA sequence :
ATGACAACATCATGCAACGGCAATTGCGCCTGCTCCTGCAGCGCCGCAGCAGAGAATGCCGGAACAGCTAAATCTGTTGA
CGCCATTGCCGTCGTATCCGGCACAGGCGCGCCGGCAGCGGTGACAGGCGCTTTTGCAGAAGCCGCGACAACAGCGGCTG
CAGTCACGGCAGATCCCGTCCTCCGCTATTATATCGACGGCCTCGACTGCGCCGACTGCGCCGCCAAAGTGGAAAAGATC
CTCTCTCAACAAGCTGGTGTGCGTTGGGTCCGCATCGATTTCGGCGCCGGCGCGCTGACCCTTTCGCCCATCGAACCGGC
TTTCTCGCTACCGACCATTACCTCGGTCGTCTCCAGCCTCGGTTACCGCCTGCGGCTGCCTGAAGGCGCCGGCGGATCGA
GGGCAGCGCAAGAGACAGGAACGATGGCGGGCAAGGAACCCCGATGGCGCCGCCTGAACCTCCGCGCGGCCAGACCGGTC
CTCTCCGGGCTTGGCTTGGCGCTGGGTCTCCTCCTCGACCAGACGGCGGCGACAGCCCTCTCCCCGCTTGCCTACGCCTT
CGCCATCGTCGCCGGAGGCTGGCCCATCGCCCGCGCCGCTTGGACAGCCCTGAAGGCGTTGACCTTGGACATGAACGTGC
TGATGCTCCTGGCTGTAGCCGGCGCCATCGCTATCCAGGAATGGTCTGAGGCGGCGGCTGTCGTCTTCCTTTTCAGCCTA
GGGGCGGTCCTGCAGGCGTCGACGCTGGACAAAACGCGTCGCTCCATCCGCTCGCTCCTTTCTCTGACGCCAGCCGTCGC
CACCGTCTCCCGCAATGGCGTCGAATCCACCGAACCAGTGGAACAGATCATCCCCGGCGATATGATCATCGTCCGCCCCG
GCGATCGGATCCCCCTCGACGGGCAAGTCCTGCGTGGCGTCTCATCGGTCAACCAGGCGCCGGTGACCGGCGAATCGACG
CCGGTGGAAAAAGAGCCCGGCGACGGCGTCTTCGCCGGCACGGTCAACGAAAACGGGCTCCTGGAGATCCTGGTCACCCG
TCCGGCTTCAGACAGCGCCGTCGCCCGCATCATCCGCCTCGTCGAAGAGGCCCAGTCGCGCCGCGCCCCCGCACAGCAGT
TCGTCGACCGTTTTGCCGCCGTCTACACGCCTACCGTGATCGTCTTAGCCGCTCTCGTGGCCGTCGTGCCGCCCCTTTTC
GGCGCCCCTTGGGAGGAGTGGTTCTACCGCGCCCTGGAACTGCTCGTCGTATCCTGCCCCTGCGCACTGGTCATCTCAAC
GCCCGTGGCTATCGTCGCCGCCATCGGCAACGGCGCCAAGCAAGGCGTACTGATCAAAGGTGGCGCCCACTTGGAGGAAC
TGGGCCGGATCAACACCATCGCCTTTGACAAGACGGGCACCCTGACTGTAGGCCGGCCGGCAGTGGCCCATTTCCTCAAC
GTGGCGCCACCGGATCAACATGATGACCAGGCGCTGCTCTCCATCGCCTGGCGCCTGGAGCGACGGTCATCGCACCCGCT
GGCGGCAGCCATCGTCCGCTTTGCCGAGGAACGCCTTCCGGCAACCGCCCATGGCGACCTATCGGAACTGAAAGGCTATG
CCACCCTGCCGGGCGCCGGTGTGTCCGCCGTCATCGGCGGTGTCCCTTATGCCCTCACGTCGCCCGGGCGCAGCCCAGTC
GCATCAGCCCTTCCGGAAAACCTTCTCGCGCAGATCGACACATGGCAGCGCGATGGCTATACGGTCAGCCTGCTTTCCGA
TGATAGGCGACCGCTGGCCCTCTTCGCCCTCTCCGACGCTTGCCGGCCGGAAAGCGGCCGCGTCTTGGCCCGCCTGAAAG
CGGCTGGCGTCAGCCATATCGCCATGCTCACCGGCGATAACAGCCACACGGCCCGCCGCATCGCCGCCGAACTGTCTATC
GACGAGGTGCACGCCGAACTGCTGCCGGCGGAAAAGGCGGAGACCGTACAGGCATTGATGCGCCCCGAGCGCCGCGTCGC
CATGGTCGGCGACGGGATCAACGACGCGCCGGCGCTGACGGCGGCCCACCTCGGCGTAGCCATGGGCGGTTACGGATCGG
ACATGGCCATGGAGACAGCCGACGTGATCCTCGCCAGCGGCAGGCTGGAACAGCTTCCCTTCGCCATCCGTCTCGGTCGC
TCAGCCTTGTCCATCATCCGGCAGAACATCATCTTCGCCCTCGTCGTCAAGGCTGTTGCCTTGCTCTTGATCCTCCCCAA
CTGGCTCAACCTCTGGCTGGCCGTCTTAAGCGACACCGGCGCCGCGCTGGTGGTCATCCTGAACGCCCTTCGCCTGCTCA
ATATCAATACCCTTTCTCCAGATCGACCACGTTAA

Protein sequence :
MTTSCNGNCACSCSAAAENAGTAKSVDAIAVVSGTGAPAAVTGAFAEAATTAAAVTADPVLRYYIDGLDCADCAAKVEKI
LSQQAGVRWVRIDFGAGALTLSPIEPAFSLPTITSVVSSLGYRLRLPEGAGGSRAAQETGTMAGKEPRWRRLNLRAARPV
LSGLGLALGLLLDQTAATALSPLAYAFAIVAGGWPIARAAWTALKALTLDMNVLMLLAVAGAIAIQEWSEAAAVVFLFSL
GAVLQASTLDKTRRSIRSLLSLTPAVATVSRNGVESTEPVEQIIPGDMIIVRPGDRIPLDGQVLRGVSSVNQAPVTGEST
PVEKEPGDGVFAGTVNENGLLEILVTRPASDSAVARIIRLVEEAQSRRAPAQQFVDRFAAVYTPTVIVLAALVAVVPPLF
GAPWEEWFYRALELLVVSCPCALVISTPVAIVAAIGNGAKQGVLIKGGAHLEELGRINTIAFDKTGTLTVGRPAVAHFLN
VAPPDQHDDQALLSIAWRLERRSSHPLAAAIVRFAEERLPATAHGDLSELKGYATLPGAGVSAVIGGVPYALTSPGRSPV
ASALPENLLAQIDTWQRDGYTVSLLSDDRRPLALFALSDACRPESGRVLARLKAAGVSHIAMLTGDNSHTARRIAAELSI
DEVHAELLPAEKAETVQALMRPERRVAMVGDGINDAPALTAAHLGVAMGGYGSDMAMETADVILASGRLEQLPFAIRLGR
SALSIIRQNIIFALVVKAVALLLILPNWLNLWLAVLSDTGAALVVILNALRLLNINTLSPDRPR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 5e-114 42
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 3e-115 42
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 2e-115 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadA YP_001681332.1 cadmium-translocating p-type ATPase BAC0298 Protein 1e-92 45
cadA YP_001681332.1 cadmium-translocating p-type ATPase BAC0092 Protein 2e-91 41