Gene Information

Name : pykA (HM1_1600)
Accession : YP_001680181.1
Strain : Heliobacterium modesticaldum Ice1
Genome accession: NC_010337
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 1617854 - 1619590 bp
Length : 1737 bp
Strand : +
Note : -

DNA sequence :
ATGCGAAGGACAAAAATCGTCTGCACCATCGGGCCGGCCAGTGAACACCCGGACACCCTGAGAGAGATCATCCGTTCCGG
CATGAACGTGGCCCGCCTCAACTTCTCTCACGGCTCCCATGAGGAACATGGACGCCGCATAGAGAACATCCGCCGCATCG
CTGCCGAACTCGGCGCCAACGTAGCCATCCTGCTGGATACCAAGGGACCGGAGATCCGCACCGGCGATTTTGCCGCTCCG
CCGATCTTTTTGGAAGCAGGTCAGCGCTTCACCTTGACGACCGATCCCATCCTCGGCGACGCCTCGCGGGTCTCCGTCAC
CTATGCCGACCTGCCCAAGGACGTGTCGCCGGGCGTCCGCATCCTCGTCGATGACGGCCTCATCGAACTGGAAGTAGAGG
CAGTCGAAGGCAACGACGTCATCTGCCGCGTCCTCAACGGCGGTAAGGTCTCCAACAAAAAAGGCGTCAATGTTCCCGGC
ATCTCCATCAACCTGCCCTCGGTCACCGAAAAGGACATCGCCGACATCCGCTTCGGCATCGAACAGAAGGTCGATTTCAT
CGCCGCTTCCTTCGTCCGCAAGGCCGCCGATGTGCTGGCTATCCGCAAGATCCTAGAAGAGGGCGGCGCTGACATCGAGA
TCATCTCCAAGATCGAGAGCAGCGAAGCGGTGGACAACCTGGACGAGATCATCCAGGCCTCTGACGGCATCATGGTCGCC
CGGGGCGACCTGGGCGTGGAGATCCCCGCCGAAGAGGTGCCTATCCTGCAAAAATCGATCATCGCCGAATGCAACCGCCT
CGGCAAACCGGTGATCACGGCCACCCAGATGCTCGACTCCATGATGAACAACCCCCGGCCGACCCGCGCCGAGGCCAGCG
ACGTGGCCAACGCCATCTTCGACGGCACCGACGCCATCATGCTCTCGGGCGAGACGGCCAACGGCAAGTACCCTGTCGTC
GCCGTTCAGACGATGGACCGCATCGCCCGGCGCGCCGAATCGTCCTTGCAAAGGAACCAGCCGGTCCACAACGGCAAGAC
CAGCGTCACCGACGCCATCGGTCAGGCCGTCTGCGTCACAGCGACCCAATTGGGGGCGGCGGCCATCATCACCGCAACAG
CCTCCGGTTACACGGCCCGCATGATCGCCCGCTACCGTCCCCAGGCGCCCATCGTCGCCGTCACCCCTCGACCGGAAGTG
CTGCGCCGTTTGGCCCTCCTCTGGGGCGTCGTTCCCTTGCCATCGGTCCAATTGACCGATACGGACCGCATGCTGGCGAC
AGCCGTCGATGTGGCCGTCGAACATGACCTGATCCAAGGCGGCGACCTCGTCGTCATCACCGCCGGCGTGCCCGTCGGCG
TGCAGGGCTCGACAAACCTGCTCAAGGTCCACACCGTCGGCAAAGCAGCGGCACGGGGCACCGGCATCGTCGCCCGGTCG
GTCACCGGCAAGGCGAGGGTTGCCCGCACCGTCACCGAAGCTGCTGACCTGCAAGCAGGCGAGATCCTCATCGCCATCGG
CACCGATGCCGACTACGTCCCTTACCTGAAAAACGCTGCCGCCATCGTCTGCGAAGAGGGCGGCCTCACCTCCCACGCCG
CCATCATGGCCTTAGAGTACCGCATCCCTGCCATCGTCGGTGTCGACAATGCCCTGTCCCTCTTTGAGACAGGGGAGACG
ATCACCGTCGACGGCCGGCGCGGCCTGATCTACCGGGGGACGGCGAAAGTCCTCTAG

Protein sequence :
MRRTKIVCTIGPASEHPDTLREIIRSGMNVARLNFSHGSHEEHGRRIENIRRIAAELGANVAILLDTKGPEIRTGDFAAP
PIFLEAGQRFTLTTDPILGDASRVSVTYADLPKDVSPGVRILVDDGLIELEVEAVEGNDVICRVLNGGKVSNKKGVNVPG
ISINLPSVTEKDIADIRFGIEQKVDFIAASFVRKAADVLAIRKILEEGGADIEIISKIESSEAVDNLDEIIQASDGIMVA
RGDLGVEIPAEEVPILQKSIIAECNRLGKPVITATQMLDSMMNNPRPTRAEASDVANAIFDGTDAIMLSGETANGKYPVV
AVQTMDRIARRAESSLQRNQPVHNGKTSVTDAIGQAVCVTATQLGAAAIITATASGYTARMIARYRPQAPIVAVTPRPEV
LRRLALLWGVVPLPSVQLTDTDRMLATAVDVAVEHDLIQGGDLVVITAGVPVGVQGSTNLLKVHTVGKAAARGTGIVARS
VTGKARVARTVTEAADLQAGEILIAIGTDADYVPYLKNAAAIVCEEGGLTSHAAIMALEYRIPAIVGVDNALSLFETGET
ITVDGRRGLIYRGTAKVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-88 52
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-88 52
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-88 52
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-87 52
pykA NP_273151.1 pyruvate kinase Not tested IHT-A Protein 8e-53 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_001680181.1 pyruvate kinase VFG0479 Protein 2e-88 52