Gene Information

Name : hemC (Fphi_0691)
Accession : YP_001677413.1
Strain : Francisella philomiragia ATCC 25017
Genome accession: NC_010336
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 729043 - 729945 bp
Length : 903 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAAACAAATAGTTATAGCTAGTCGCGAAAGCAAACTAGCATTGTGGCAGACAAATTACGTCAAAGACCGAATTCAACA
AGAGCTAAATATTCGTTGTCAGATAAATACTATGAAAACACAAGGGGATATTATTCTTGATAAGCCTCTTAATAAAATTG
GTGGTAAGGCATTGTTCATGAAAGAGCTAGAAATAGCGATGCTTAATAACAAAGCCGATATTGCTGTACACTCTCTTAAA
GATGTACCTTATCAATTGCCTCAAGGTTTTTGTTTATCAAGCTTTATGCCCAGGGAAGACCCTAGAGATGCCTTTGTGTC
AAATAAATATAGTAGCATAGATGATTTGCCAAGAGGTGCAATCGTTGGTACATCAAGTTTACGTCGTAAAGCTCAACTTT
TGCATTATAGGTATGATCTTGAGATTAGAGATTTAAGAGGAAATGTTCAAACAAGATTATCAAAGCTTGACAATGGCGAC
TATGATGCGATTATCCTAGCAAGTGCGGGTCTTATTCGTTTAGAGCTTAATGAGAGGATAACACAGTTCATTCCTGTAGA
AATATCTTTACCAGCTGTGGGTCAGGGTATAGTAGTTATAGAAGCTTTGGATAAAAGTAGTGAAATTTTACAAAAGTTAC
AAAAGCTAAACTGCAGTGATAGCTTTTGTGTTGCGACTGCTGAAAGAGCGTTCAATCAAGAGCTAAAAGGAGGCTGTCAT
GTTGCAATTGGTGCATATGCAGAGTTACATGATAATCAGATAACTCTTACAGCAATGGTTGCAAGTAGTGATGGTAAAAA
CATCTTAAAAAGAAAACTTACAGGAGATGATCCTATGAGGCTCGGTAAATTACTAGCTCAAGAAATGATCGAGCTAGGAG
CATATAAAATATTGGAGAAATAA

Protein sequence : 
MKQIVIASRESKLALWQTNYVKDRIQQELNIRCQINTMKTQGDIILDKPLNKIGGKALFMKELEIAMLNNKADIAVHSLK
DVPYQLPQGFCLSSFMPREDPRDAFVSNKYSSIDDLPRGAIVGTSSLRRKAQLLHYRYDLEIRDLRGNVQTRLSKLDNGD
YDAIILASAGLIRLELNERITQFIPVEISLPAVGQGIVVIEALDKSSEILQKLQKLNCSDSFCVATAERAFNQELKGGCH
VAIGAYAELHDNQITLTAMVASSDGKNILKRKLTGDDPMRLGKLLAQEMIELGAYKILEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-64 52
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-64 52