Gene Information

Name : smpB (Fphi_0056)
Accession : YP_001676777.1
Strain : Francisella philomiragia ATCC 25017
Genome accession: NC_010336
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 52767 - 53240 bp
Length : 474 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAGTAAACATAAGGTTTCTCCAGCAACTATTGCTAGAAATAAAAGAGCCTTCCATGATTATACTATTCTAGAGAAATT
TGAAGCTGGAATAGTACTACAAGGATGGGAGGTAAAAAGTATCAGAGCTGGTAAAGTACAGATGATAGATAGCCATGTGC
ATATCAAGCGTGGCGAAGCTTGGCTTTTTAATTGTCTAATAACTCCTCTACTCTCTGCATCTACTCATGTGGTAGCTGAT
GCTTCAGCAAATCGTAAACTACTACTTAATCGCCGTGAGATAGACAAAATCATGGGACGAATTGAGCAAAAGGGATTTAC
CTGTGTGCCTTTAGCTATGTATTGGAAAGGTCCTCGTGTAAAAGTTGAAATAGCTCTTGCTCAGGGTAAAAAAGTTCACG
ACAAGCGTCAGGCTCAAAAAGATAAGGATTGGGCTCGCGAAAAGGATAGAATCTTTAAGAAGGCGCATAGATAA

Protein sequence :
MSKHKVSPATIARNKRAFHDYTILEKFEAGIVLQGWEVKSIRAGKVQMIDSHVHIKRGEAWLFNCLITPLLSASTHVVAD
ASANRKLLLNRREIDKIMGRIEQKGFTCVPLAMYWKGPRVKVEIALAQGKKVHDKRQAQKDKDWAREKDRIFKKAHR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 4e-34 52
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-19 44
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 5e-19 44