Gene Information

Name : lspA (Fphi_0398)
Accession : YP_001677116.1
Strain : Francisella philomiragia ATCC 25017
Genome accession: NC_010336
Putative virulence/resistance : Unknown
Product : lipoprotein signal peptidase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0597
EC number : -
Position : 450863 - 451411 bp
Length : 549 bp
Strand : +
Note : lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis

DNA sequence :
ATGAAGAATATCAAGATATCTGCAGTCGTTGCGTTGAAAATATTACTACAGAAGCTGGAGAATCACGTGAATTCGCTTAA
ACCTAAGCTTAAATATTTCATCTTAGCATTTATTATTATAGTTGTAGATTTATACACGAAATATTTAGCTAATACTTGGC
TTGAATTTGCCCAACCCGTAAAAGTGACTAGCTTCTTTAATTTTACTTTACTATACAATCATGGAGCTGCATTTAGCTTA
CTGAGCAATGATCAAACATCATGGCAAATGATTATGTTTGCCACTATTTCATTAATCGCTGCAATTGTGCTTATATATCT
AATAGTCAGACAACCTACTAGTGCAAGACTTAACCTAATCTCATTCTCACTTATATTAGGAGGAGCTCTAGGTAACTTCT
ATGATAGAGCTTTTCAAGGTTACGTTATAGACTTTTTAGACTTTCATATCGGTAATTATCACTGGCCATCTTTTAATACA
GCTGATTCAGCAATAACCTGTGGTGTAATACTTCTGATACTTGCTTCGTTATTTACCAAAAAATTATAA

Protein sequence :
MKNIKISAVVALKILLQKLENHVNSLKPKLKYFILAFIIIVVDLYTKYLANTWLEFAQPVKVTSFFNFTLLYNHGAAFSL
LSNDQTSWQMIMFATISLIAAIVLIYLIVRQPTSARLNLISFSLILGGALGNFYDRAFQGYVIDFLDFHIGNYHWPSFNT
ADSAITCGVILLILASLFTKKL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lspA CAJ77096.1 Lipoprotein signal poeptidase Not tested AbaR1 Protein 6e-15 45
lspA ADZ05771.1 lipoprotein signal peptidase Not tested AbaR11 Protein 6e-15 45
lspA AGK36655.1 lipoprotein signal peptidase Not tested AbaR26 Protein 6e-15 45
ACICU_00236 YP_001844895.1 lipoprotein signal peptidase Not tested AbaR20 Protein 9e-15 45
lspA ACN81031.1 lipoprotein signal peptidase Not tested AbaR5 Protein 9e-15 45
lspA AAN62189.1 putative lipoprotein signal peptidase LspA Not tested PAGI-2(C) Protein 2e-13 42