Gene Information

Name : Fphi_1861 (Fphi_1861)
Accession : YP_001678588.1
Strain : Francisella philomiragia ATCC 25017
Genome accession: NC_010336
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 1991702 - 1992454 bp
Length : 753 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGGTTAATATTCATGTTGTAATCCCTGCTAGGCTTAAATCAACACGCCTACCTGGTAAGATGCTTGCAGATATCGCAGG
TAAGCCAATGATTCAAAGAGTATATGAACAGGTAGCTAAATCAAAATTTAAGAGCATAATTATAGCTACAGACTCTCAAG
AAATAAAAGAAGTTGCAGAAAATTTTGGTGCAAAAGTAATCTTGACAAGAGATGATCATGAGTCTGGTACAGATAGGATA
GCTGAGGCTGTTACTAAGCTAGGTTTTGCCGATGAAGATATTGTTGTCAATGTGCAGGGTGATGAACCTTTGATCCCTGT
TGAAAATATCGAACAAGCAGCACAATTATTAATCGAAAAGCCAGAAGCAGTTGTCTCAACACTATGTGAGAGAATTACTG
AAGCAGAAGATATATACAACCCAAATAATGTCAAAGTTGTTTTTGATAAAAATAACTATGCTTTGTATTTTAGTAGAGCA
TCAATCCCTTTTGAAAGAGGCTTTTCGGAGAATCATCAAGTCAGTATATCTGAATTCTTTAGGCATATTGGTATATATAC
TTATAGAGTTGGCTTTTTGAAGCACTATGCGGAGCTTGCAATATCACCAATCGAAAAATATGAAGCTCTTGAGCAATTAA
GAGTATTATATAATGGTTATAAAATTGCTATTGAACAATCAGCTAAACCAACTCCTGCAGGTGTTGATACGCTTCAAGAT
TTAGAAAAAGTAAGGAAACTATTTGATGTTTAA

Protein sequence : 
MVNIHVVIPARLKSTRLPGKMLADIAGKPMIQRVYEQVAKSKFKSIIIATDSQEIKEVAENFGAKVILTRDDHESGTDRI
AEAVTKLGFADEDIVVNVQGDEPLIPVENIEQAAQLLIEKPEAVVSTLCERITEAEDIYNPNNVKVVFDKNNYALYFSRA
SIPFERGFSENHQVSISEFFRHIGIYTYRVGFLKHYAELAISPIEKYEALEQLRVLYNGYKIAIEQSAKPTPAGVDTLQD
LEKVRKLFDV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-41 43
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-41 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-41 43