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Name : leuS (Fphi_1752) Accession : YP_001678479.1 Strain : Francisella philomiragia ATCC 25017 Genome accession: NC_010336 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 1880187 - 1882628 bp Length : 2442 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGAGCGAATATAACTTTACTCAGATTGAGCAACAAGCTCAAGAATACTGGCGTGAAAATAATTCTTTTAAAGCTGTAGA AGATAAAAATAAAGAAAAATTCTATTGTTTGTCAATGTTACCATATCCAAGTGGTACCCTTCATATGGGACATGTGCGTA ATTATACGATTGGAGATGTAATTGCAAGATATCAAAAGATGCAAGGTAAGAATGTCCTTCATCCTATGGGTTGGGATGCA TTTGGATTACCTGCCGAAAATGCTGCAATAAAACATAAAAAATCTCCTTATGAGTGGACAAAAAGCAATATTGCATATAT GAGATCGCAGTTGGATTCTCTTGGGTTTAGCTTTGATTGGTCTAGAGAGGTCGCAACTTGTGATGAAAGTTATTATAAAT GGGAACAATGGTTCTTTATCCAGCTTTACAAAAAAGGCTTGGCATATCGCAAAAACTCGGTTGTAAACTGGGATCCTGTT GATCAAACTGTTTTAGCGAATGAGCAAGTTGTAGATGGTAGAGGCTGGAGATCTGGAGCCCTAATTGAAAAGAAAGAGAT TCCACAATGGTTCTTAAAAATAACTGATTATGCAGATGAGCTTCTAAAAGATATTAATCAATTAGATGGTTGGCCAGAAG CTGTGAAGACTATGCAGACTAACTGGATTGGTAAATCAAAAGGTCTGACTGTTAAGTTTAAAATTCAAAACTCTGATAAG GAAATCGAAGTATTTACAACTCGTCCAGATACTCTTATGGGAGTTAGTTATCTAGGTATAGCACCTGAGCATCCTCTTGC TCTTGAAGAAGCAAAAACAAACTCTCAATTAAAATCATTTATAGATGAGTGTAAAAGAATCTCTACTATGGAAGCTGATT TAGCAACTCAAGAAAAGAAAGGCTTTAAAACTTCAATACAAGCAATCCACCCTATCTCAGGAGAAACAGTTAATGTTTGG GTAGCAAACTTTGTACTTATGGGATACGGTTCTGGAGCTGTAATGTCAGTCCCAGCACATGATCAAAGAGATTGGGAATT TGCACAGAAATATAATATTGCTTTAAAACAAGTTATTAAGCCTAGTGATAATAAGTCAAAATTAGACTTAGATAAAGAAG CATTTACTGAAAAAGGTATTTTGATTAATTCAGGTGAATTTGATGGTTTAAATTTTAAATCTGCTTATCAAGCGATTAAA AAATATCTTTTTGACAATGATAAAGGTTATGAAACTACAAATTTTAGAATTCATGATTGGGGTATTTCACGTCAAAGATA TTGGGGATGCCCTATTCCTATGATCCATTGTAATGATTGTGGATTAGTACCAGAAAAAGAAGAAAATTTACCAGTTAAAT TACCAACTAATGTAACTCTTACAGAAGCAGGCTCTCCACTTAAAGATATACCAGAATTTTTAAATGTAGCATGTCCAAAT TGTGGTAAACCAGCAACTAGAGAAACGGATACATTTGATACATTCTTTGAATCATCTTGGTATTATGCAAGATATACATG CCCTACTGCTGATAAGATGTTAAGTGAAGAAGCTAACTATTGGCTACCAGTTGATAAGTATATTGGTGGAATTGAGCATG CTATTATGCATCTATTATATGCAAGATTTTTCCATAAATTAATGAGAGATCAAGGACTAGTTACATCTGATGAACCATTT AAAAACTTACTTACTCAAGGTATGGTGCTAAAAGATGGTGCTAAAATGTCTAAATCTAAAGGGAATACTGTAGACCCCCA AGAGCTTATCGATAAATATGGTGCAGATACTGTTAGATTATTTAGTATGTTTGCAGCACCTCCTGAGCAATCACTTGAGT GGTCTGATACTGGAGTTGATGGTGCTAATAAGTTTTTGCGTAAAGTATATAATTATGCTTATACAAACAAAGAAATCTTG GCTAAAAATATAACTATAGATGTAACTAAATTATCAAAAAATGATAAGAAAGCTCGTTATGAGATATATGCTAATTTAAA ACAAGCTATTTTTGATTTTGATAAAAGTCAATTTAATACAGTTGTTTCAGCATGTATGAAAATTTTAAATACGCTTAACA ATTATGATAATTTATCTGATAGTGTTAAGTTAGAGGGTTTTAGTATTTTATTAAGGATATTATCACCTTTCACACCACAT ATTTGTCATTATTTATGGCAAGAAATTGGCTTAGGTGAAGATATTTTGCATACACAATTTCCTACTGTTGATGACATAGC TCTTGAGAAGGACGAATTTTTATTAGTTGTACAAATTAACGGTAAAGTTAAAGTAAAACTTGAATTAGATGCCTCATTAA CAAAAGAGCAAGTTGAACAAGAGGTATTATCTGATGAGCAGATTAAAACTTTTATCAAAGATAAACAAATAGTCAAAGTT ATATATGTGCCTCAGAAATTAATTAATATTGTAGTCAAATAG Protein sequence : MSEYNFTQIEQQAQEYWRENNSFKAVEDKNKEKFYCLSMLPYPSGTLHMGHVRNYTIGDVIARYQKMQGKNVLHPMGWDA FGLPAENAAIKHKKSPYEWTKSNIAYMRSQLDSLGFSFDWSREVATCDESYYKWEQWFFIQLYKKGLAYRKNSVVNWDPV DQTVLANEQVVDGRGWRSGALIEKKEIPQWFLKITDYADELLKDINQLDGWPEAVKTMQTNWIGKSKGLTVKFKIQNSDK EIEVFTTRPDTLMGVSYLGIAPEHPLALEEAKTNSQLKSFIDECKRISTMEADLATQEKKGFKTSIQAIHPISGETVNVW VANFVLMGYGSGAVMSVPAHDQRDWEFAQKYNIALKQVIKPSDNKSKLDLDKEAFTEKGILINSGEFDGLNFKSAYQAIK KYLFDNDKGYETTNFRIHDWGISRQRYWGCPIPMIHCNDCGLVPEKEENLPVKLPTNVTLTEAGSPLKDIPEFLNVACPN CGKPATRETDTFDTFFESSWYYARYTCPTADKMLSEEANYWLPVDKYIGGIEHAIMHLLYARFFHKLMRDQGLVTSDEPF KNLLTQGMVLKDGAKMSKSKGNTVDPQELIDKYGADTVRLFSMFAAPPEQSLEWSDTGVDGANKFLRKVYNYAYTNKEIL AKNITIDVTKLSKNDKKARYEIYANLKQAIFDFDKSQFNTVVSACMKILNTLNNYDNLSDSVKLEGFSILLRILSPFTPH ICHYLWQEIGLGEDILHTQFPTVDDIALEKDEFLLVVQINGKVKVKLELDASLTKEQVEQEVLSDEQIKTFIKDKQIVKV IYVPQKLINIVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-153 | 41 |
