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Name : guaA (Fphi_1717) Accession : YP_001678443.1 Strain : Francisella philomiragia ATCC 25017 Genome accession: NC_010336 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : - Position : 1843974 - 1845524 bp Length : 1551 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGACAGATATACATAATCATAAGATTTTGATTTTAGATTTTGGTTCGCAATATACTCAACTTATCGCTCGTAGAGTGAG AGAGGTTGGTGTCTTTTGCGAAATATTTCCTCACGACATAGCAGATGATTTTATCAAAGATTATCATGCTAAAGGTATAA TTCTTTCTGGTGGTCCTGAGTCTGTATATGATTCAGATGTTAAGGCTCCGGAAATAGTCTTTGAATTAGGTGTTCCTGTT TTGGGTATCTGCTATGGTATGCAAACAATGGTAATGCAGCATGGTGGAGAGGTAAAAGGAGCTGATCAAAGTGAGTTTGG TAAAGCGATCGTTAATATCTTAAAATCATCAGAAAATATATTTTCTAATCTCAAAACAGAGCAGTCTGTATGGATGAGTC ATAGTGATAAAGTTACTCAAACTGGCGAACATTTTGAAGTAATAGCATCATCAACTAATGCTCCTGTTGCAGCTGTTGCT CACAAGAGTAAACCTTTTTATGGAGTACAGTTTCATCCAGAAACTACTCATACAGAGAACGGTAAACAGATTATAGAAAA TTTTGCCTTAAATATCTGTAAATGTGATGCTCTTTGGAATATCGAAAATATTATTGAAAACGATATCAAAGAAATAAAAA AACAGGTTGGAAGTGATAGAGTAATTTTAGGCTTATCAGGTGGTGTTGACTCATCTGTGGTAGCAGCAATATTACATGAA GCTATTGGTGATCAACTTACCTGTATATTTGTAGATACTGGACTACTTCGTCTTAATGAAGGCGACCAAGTGATGGAAGT ATTTGCAGAGCATATGGATATTAATGTTATTCGTGTAAATGCTAAAAATAGATTTTTAGATGCTCTAAAGGGTATTGGTG ATCCTGAAGAAAAGCGTAAAATCATAGGTAAGCTTTTTGTTGATATTTTTGATGAAGAAGCAGCTAAAATCGAAAATGCG AAATGGCTTGCTCAAGGCACGATCTATAGTGATGTAATTGAGTCAGCTGGTAATAGCCAATCTAAAGCTCATGTTATTAA ATCTCATCATAACGTTGGTGGTTTGCCAAAAGAGATGAAGCTTAAGCTATTAGAACCTCTAAGAGAGTTATTCAAAGATG AGGTGCGTAAATTAGGACTAGGCTTAGGCTTACCGTATAATATGCTTTATAGACATCCGTTCCCAGGTCCAGGTCTTGGT GTGCGTATATTAGGTGAAATTAAGAAAGAGTATGTTGAAACTCTACAAAAAGCAGATGCTATCTTTACTGAAGAGCTCTA TAAGCATAATTTGTATCATGATATTTCTCAGGCCTTCGGGGTTTTCTTACCAGTTAAGTCAGTTGGGGTTGTTGGGGATC AGCGTAGATATGAATATGTTATAGCATTAAGAGCTGTGGTTAGTATTGATTTTATGACTGCAACATGGGCAAATTTGCCT TATGACTTCTTATCTATAGTTTCAAATAGAATTGTAAATGAAGTTAAACAAGTATCACGAGTCGTTTATGATGTAACAGG TAAACCACCTGGAACAATTGAGTGGGAATAA Protein sequence : MTDIHNHKILILDFGSQYTQLIARRVREVGVFCEIFPHDIADDFIKDYHAKGIILSGGPESVYDSDVKAPEIVFELGVPV LGICYGMQTMVMQHGGEVKGADQSEFGKAIVNILKSSENIFSNLKTEQSVWMSHSDKVTQTGEHFEVIASSTNAPVAAVA HKSKPFYGVQFHPETTHTENGKQIIENFALNICKCDALWNIENIIENDIKEIKKQVGSDRVILGLSGGVDSSVVAAILHE AIGDQLTCIFVDTGLLRLNEGDQVMEVFAEHMDINVIRVNAKNRFLDALKGIGDPEEKRKIIGKLFVDIFDEEAAKIENA KWLAQGTIYSDVIESAGNSQSKAHVIKSHHNVGGLPKEMKLKLLEPLRELFKDEVRKLGLGLGLPYNMLYRHPFPGPGLG VRILGEIKKEYVETLQKADAIFTEELYKHNLYHDISQAFGVFLPVKSVGVVGDQRRYEYVIALRAVVSIDFMTATWANLP YDFLSIVSNRIVNEVKQVSRVVYDVTGKPPGTIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 7e-124 | 55 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 5e-124 | 55 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 4e-124 | 55 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 2e-99 | 47 |
