Gene Information

Name : Fphi_0173 (Fphi_0173)
Accession : YP_001676895.1
Strain : Francisella philomiragia ATCC 25017
Genome accession: NC_010336
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 177973 - 179253 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATGCTAAATATATTAAAGATAATTTAGAAGAAGTAGCTGAGAAACTCGCAACTAGAGGTTATCAGTTTGATAT
AGCAGAATTCAAAGCTCAAGAAGCAAAAAGAAAAGACCTTCAAGAGAGAACTCAGGAACTTCAATCTCAACGTAATACTA
TCTCCAAAGAAATAGGTAAAAGAAAGTCTAAAGGTGAAGATGCTAGTGACATTTTTGCCAAAGTTAATGATATCAACGAT
GAACTAAAAGTAATCGAAAAAGTGCTTAAAGATCTTCAAGACTGTATAAATAATACTCTTCTGTCAATGCCAAATCTTCC
AGCTGATGATGTACCAGTTGGTAAGGATGAGAGTGAAAATGTCGAGATAAAAAAATGGGGAACTCCTCGTGAATTTCACC
CTGAAGCTCAAGCTAAAGATCATGCAGATATTGGCGAAATACTTAATATGATTGACTTCAAAGCTGCAGCAAAAATTACA
GGTAGTCGATTTGTAGTTCTAAAAAGTAAAATTGCTAAGCTTCATCGTGCATTGACACAATTTATGTTAGATATGCATAC
AGAAAAGCATGGCTATGAAGAATTATATGTGCCATATATGGTAAATAATGATAGTTTATATGGAACAGGCCAGTTGCCTA
AATTCTCTGAAGATTTGTTTAAATTAGAAGGTGACTTTGAGTATAGCCTAATACCAACGGCAGAAGTACCTATCACAAAT
CTAGTAAGAGATGAAATCTTAGATACAGAATCTCTACCTAGATACTACACGGCACACACACCATGTTTTAGAAGTGAGGC
TGGCTCTTATGGGCGAGATACTAAAGGATTGATTCGTCAACATCAGTTTGAGAAAGTTGAATTAGTGCATATCACTATAG
CTGATAAAGGTGAAGAATCTTTGGAGCTCTTAACATCTCATGCAGAAAAAGTACTACAAAAACTAAACCTACCATACAGA
GTAGTCAAACTATGTACGGGAGATATGGGTTTTAGTGCGAAAAAAACCTATGATCTAGAAGTTTGGATACCTTCACAAAA
TACTTATAGAGAAATATCATCATGTAGCTGGTGTGGAGATTTCCAAGCTCGTCGCATGAAAGCTAGACACAAAAATCCAA
GTATGAAAAAACCTGAATTGGTACATACTTTAAATGGTTCTGGTTTAGCAGTTGGCAGAACATTACTAGCTATTATTGAG
AATTACCAACAAGAAGATGGATCTATCATGATTCCTGAAGCACTTATTAACTATATGGGTGGAATTTCTGTTATTAAGTA
A

Protein sequence :
MLDAKYIKDNLEEVAEKLATRGYQFDIAEFKAQEAKRKDLQERTQELQSQRNTISKEIGKRKSKGEDASDIFAKVNDIND
ELKVIEKVLKDLQDCINNTLLSMPNLPADDVPVGKDESENVEIKKWGTPREFHPEAQAKDHADIGEILNMIDFKAAAKIT
GSRFVVLKSKIAKLHRALTQFMLDMHTEKHGYEELYVPYMVNNDSLYGTGQLPKFSEDLFKLEGDFEYSLIPTAEVPITN
LVRDEILDTESLPRYYTAHTPCFRSEAGSYGRDTKGLIRQHQFEKVELVHITIADKGEESLELLTSHAEKVLQKLNLPYR
VVKLCTGDMGFSAKKTYDLEVWIPSQNTYREISSCSWCGDFQARRMKARHKNPSMKKPELVHTLNGSGLAVGRTLLAIIE
NYQQEDGSIMIPEALINYMGGISVIK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-107 56