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Name : thyA (Fphi_1432) Accession : YP_001678158.1 Strain : Francisella philomiragia ATCC 25017 Genome accession: NC_010336 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 1565661 - 1566485 bp Length : 825 bp Strand : - Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : ATGCGAGAATATCTAAACTTTCTAAAATATATAAAAGACAATGGAACTAAGAAAGGCGATAGAACAGGTACTGGTACAAC AAGTATTTTTGGATACCAAATGCGCTTTGATTTACAACAAGGTTTCCCATTAGTAACTACAAAAAAAATTCATATCCCAA GTGTTGTTCATGAACTGTTATGGTTTTTAAGTGGTAGCACAAATGTAAAATATCTAAATGATAATAAAGTTAGAATTTGG AACGAATGGGCAACTGAAGAAGGTGAACTTGGACCGATATATGGTAAACAATGGCGTGACTTCAATGGCGAAGGTATAGA TCAAATTGCTGAAGTAATTGAAATGCTAAAAACCAATCCAAATTCACGTAGAATTCTTGTCTCAGCATGGAATCCTTGTG TTGTTCCTTCAGAAAAAATCTCTCCTCAAGAGAATGTCGCTAAAGGTAATTCTGCCCTACCACCTTGTCATGCAATGTTC CAGTTTTATATTGCTGATAATAAGTTATCTTGTATGCTTACACAAAGAAGTGCTGATGCCTTTTTGGGAGTTCCATTTAA TATTGCGAGCTACTCTTTACTAACACACATGATTGCTCAGCAATGTGACCTTGATGTTGGTGAATTTATTTGGTCTGGTG GCGATTGTCATATTTATAACAATCATATAGAGCAAGTAAATGAGCAGCTTAGTAGAGAGCCTTTAGACTTACCAACGCTT AAAATTTTAAGAAAACCAAGTTCTATATTTGATTACAAATATGAAGACTTTGAATTTCAGAATTATAAACATCATCCAGC TATAAAAGCAAAAATTTCTGTATAA Protein sequence : MREYLNFLKYIKDNGTKKGDRTGTGTTSIFGYQMRFDLQQGFPLVTTKKIHIPSVVHELLWFLSGSTNVKYLNDNKVRIW NEWATEEGELGPIYGKQWRDFNGEGIDQIAEVIEMLKTNPNSRRILVSAWNPCVVPSEKISPQENVAKGNSALPPCHAMF QFYIADNKLSCMLTQRSADAFLGVPFNIASYSLLTHMIAQQCDLDVGEFIWSGGDCHIYNNHIEQVNEQLSREPLDLPTL KILRKPSSIFDYKYEDFEFQNYKHHPAIKAKISV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 1e-69 | 60 |
| thyA | YP_189147.1 | thymidylate synthase | Not tested | ¥ÕSP¥â | Protein | 2e-44 | 42 |
