Gene Information

Name : Fphi_1133 (Fphi_1133)
Accession : YP_001677858.1
Strain : Francisella philomiragia ATCC 25017
Genome accession: NC_010336
Putative virulence/resistance : Virulence
Product : DNA mismatch repair protein MutS
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0249
EC number : -
Position : 1221684 - 1224230 bp
Length : 2547 bp
Strand : -
Note : This protein performs the mismatch recognition step during the DNA repair process

DNA sequence :
ATGCAAGAAGTTTCAAATCACACACCAATGATACAGCAATATTTGAAAATTAAATCTCAATATCCAGATATATTACTGTT
TTATCGAATGGGTGACTTTTACGAGCTTTTTTTTGATGATGCAAAAAATGCTGCAGAACTACTAGATATAACCCTCACTG
CTCGAGGAAAATCAAATGGTGATTCAATACCAATGGCTGGTGTGCCATATCACGCTGCAGAAGGCTACATCGCTAAAATT
GTCAAAAAAGGATTATCAGTTGCAATATGTGAGCAAATAGGAGATCCAAGCACCTCAAAAGGTCCAGTTGAACGACAAGT
TACACGTATAATAACTCCAGCTACAGTTTCTGAAGAGGCTTTTTTAGATAGTAATCAAGATAGCATTCTCGTAAGTATAT
ATGAAAAAAACAATAAATATCACATCGCATATACTAGCTATACTCAAGGCAAAATTCATCTTATAAATACGGTAACAAAT
TCATCTGATCTAAAAAATCAGATATTAAAACTATCACCTCAAGAGATAATTACCAACTCTAATAGTCTTGTAGAAAAGAA
TATTTTCAACAAACCAGTAAAAGTTTTGGAAGAATGGTACTTTAGTAATTTTGAAGCAAAAAAGCATATACTAAATTCTT
TTGATAACAGTTTTGCAAATAACATTCTAAATTTATATAAAAAAGAACAACTAACTGTTATCGGATCAATACTTGCTTAT
TTAACAAATACACTAAAAAGTACGCCTAAGCACATCTCAGATATCCTCCTAGATGAAGATCAAAACATACTAAATATAGA
TATTAATAGTAGAAATAATTTAGAACTAGATAATAATTCAAAAAGCAGCCTTCTAAACATAATGGATAAATGCAAAACTA
GTTTAGGTAGCAGGCTTCTAAGAAGATACTTCAAAAATCCTACTCGGGATCTAAACAAAATTTCTTTGCGTCATAACGTT
ATAAAATCCTTCAAGCAACACCATTATTTCTTAAAAATTCAGGATATTCTGTCTTATATAAATGATATTGAAAGGATAAT
TTCTCGCGTTGCTCTAGGAACAGTAAAACCTAAAGATCTAGTCTCTCTTAATAGCTCTCTCGAGCAACTACCTAAACTCA
AGAGTCTACTTGAAAAAATAAACACCTCTGAGATTATAAATATAAACAATCACATTCATCAAATTGATGAGCTGACAAAA
CTACTAAACAAAGCCATTGTAGATAATCCTCCAATGACCATTCGCGATGGTGGCGTCATAAAACATGGTTTCGACCAGGA
ACTTGATGAGTTAAGAGGGCTAAAAGACAACTCTTACGATTTTTTATTAAAATTTGAAACTCTGCAAAAGCAAAAAACGG
GGATTAATACACTAAAAGTTGGTTATAACCGTGTACATGGTTATTACATTGAACTTTCGAAACAATATGCTGATAAAGTC
CCAACAGAGTATATCAGACGCCAAACATTAAAAGCTAGTGAGCGCTATATTACTGACGAGCTAAAAGCTTTTGAGGATAA
GATTCTCTCAGCGAAAGAAAAAGCTTTAGCTAGAGAAAAGCTTATCTACGATACTCTATTGAATAAAGTTCTAGAATACT
ACTCTCAAATCCAGCAGACTGCAGCAAGTATTGCAAAAATAGATGTCTTAGCAAACTTTGCAGAAAGAGCTATCAAACTA
AACCTAAATCAACCTAAATTTAATAAAACTGGTAAATTGGATATAAAAGAAGCTCGTCATCTAGCAATCGAGCAAAATAT
TGATGAGCCCTTTATACCCAATGACACCCTATTAAGTACAGACACTTATACGTTAGAAATAATCACTGGACCTAACATGG
GGGGTAAGTCCACTTATATGCGTCAAGTTGCTCAACTTATCTTTCTAGCATATATAGGCTCATTTGTACCAGCTAGCTAT
GCAGATATTGGCGATATAGATACCATATACACTCGGATTGGTGCCTCAGATGACATATCTAGTGGTAGATCAACATTCAT
GGTTGAAATGACTGAAACAGCTTATATCCTGAATAATGCAACTAAAAAGTCTCTAGTAATCATGGATGAAATTGGTAGAG
GGACAAGTACTTTTGATGGCTTATCACTTGCGAAAGCTTGTGCAGAAAAATTTGCAAAAATTGGTGCAATGACCCTTTTT
GCCACGCATTACTTTGAGCTTACAGAGTTAGTTAATCAATATCCAAATACAAAGAATATTCATTTTGAGGCTAAAGAATA
TAAAGACAATATCTATTTCATGCACAAGGCAGTTGCTGGTGCCGCTAAAAAATCTTATGGTATTCAAGTAGCTAAATTAG
CTGGTATTTCAAAAGATGTTTTAGATTCAGCAAAGAAAAATCTAGCTAATTTAGAAAAAGGTCAAGATAAATTAGATACT
ATTGATCAGCCTCAACAAAATCTCCAACTTGATCAAACTCCACAAAAGAATCATATTAAAGAGCGACTTGAAACAATAGA
TATCAACTCAATAACACCTATCGAGGCTCTAAATATACTCTTTGAGCTAAAAAAAACTCTAATTTAG

Protein sequence :
MQEVSNHTPMIQQYLKIKSQYPDILLFYRMGDFYELFFDDAKNAAELLDITLTARGKSNGDSIPMAGVPYHAAEGYIAKI
VKKGLSVAICEQIGDPSTSKGPVERQVTRIITPATVSEEAFLDSNQDSILVSIYEKNNKYHIAYTSYTQGKIHLINTVTN
SSDLKNQILKLSPQEIITNSNSLVEKNIFNKPVKVLEEWYFSNFEAKKHILNSFDNSFANNILNLYKKEQLTVIGSILAY
LTNTLKSTPKHISDILLDEDQNILNIDINSRNNLELDNNSKSSLLNIMDKCKTSLGSRLLRRYFKNPTRDLNKISLRHNV
IKSFKQHHYFLKIQDILSYINDIERIISRVALGTVKPKDLVSLNSSLEQLPKLKSLLEKINTSEIININNHIHQIDELTK
LLNKAIVDNPPMTIRDGGVIKHGFDQELDELRGLKDNSYDFLLKFETLQKQKTGINTLKVGYNRVHGYYIELSKQYADKV
PTEYIRRQTLKASERYITDELKAFEDKILSAKEKALAREKLIYDTLLNKVLEYYSQIQQTAASIAKIDVLANFAERAIKL
NLNQPKFNKTGKLDIKEARHLAIEQNIDEPFIPNDTLLSTDTYTLEIITGPNMGGKSTYMRQVAQLIFLAYIGSFVPASY
ADIGDIDTIYTRIGASDDISSGRSTFMVEMTETAYILNNATKKSLVIMDEIGRGTSTFDGLSLAKACAEKFAKIGAMTLF
ATHYFELTELVNQYPNTKNIHFEAKEYKDNIYFMHKAVAGAAKKSYGIQVAKLAGISKDVLDSAKKNLANLEKGQDKLDT
IDQPQQNLQLDQTPQKNHIKERLETIDINSITPIEALNILFELKKTLI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mutS AAA80578.1 DNA mismatch repair protein Virulence SPI-1 Protein 5e-164 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Fphi_1133 YP_001677858.1 DNA mismatch repair protein MutS VFG0562 Protein 0.0 46