Gene Information

Name : guaA (Shal_1377)
Accession : YP_001673603.1
Strain : Shewanella halifaxensis HAW-EB4
Genome accession: NC_010334
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 1656605 - 1658182 bp
Length : 1578 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGCAACATTCATGAGCATAAGATCCTCATTTTAGATTTTGGATCGCAATACACTCAACTGATCGCCCGTCGTATTCG
TGAAATCGGTGTGTATTGTGAACTTTGGGCTTGGGATGTTTCTGAAGAGCAAATTCGTGAATTTGCTCCAAACGGCATTA
TCTTAGCCGGTGGCCCTGAAAGTGTTACCGCTGAGAACTCACCACGCGCTCCAGAATATGTGTTTAACGCTGGCGTACCA
GTACTCGGTATTTGTTACGGCATGCAAACCATGTCTGAGCAGCTTGGCGGTAAAGTGATCCAAGGTGTGGGTGAAGGTGA
GTTTGGTTACGCTCAAGTAGAAGTACAAACTGAATCTGCACTATTTAAAGCTATCGAAGATGCGGTTAGCGAAACGGGCA
AGCCACTACTTGATGTATGGATGAGCCACGGTGACAAGGTGTCTGCAATTCCTGAAGGTTTTGTTGCCGTTGCTAAAACT
GAAACTTGTCCGTTTGCCGCTATGGCCAATGAAGATAAGCAGTTCTACGGCGTTCAGTTCCACCCTGAAGTGACTCACAC
TCGTCAAGGTAAGCGCATGCTTGAGCATTTTGCTCTAGAAATTTGTGCTTGTGCTGCAAACTGGAAACCTGCTTCAATCA
TCGAAGATGCGATTGAGCGCTTAAAAGCTCAGATCGGTGATGATGAAGTTATCTTAGGTCTATCTGGTGGTGTGGATTCA
TCCGTTGTTGCTATGCTACTACACCGCGCGATTGGCGATAAGCTAACTTGTGTGTTCGTTGATAACGGACTACTGCGTCT
TAACGAAGCTGAGCAAGTCATGGAGATGTTTGGTGATCATTTTGGTCTAAACATCGTTCATGTTGATGCTGAAAACCGTT
TCTTAGATGCAATGGCTGGCGAAGCTGAGCCTGAAGCAAAGCGTAAGATCATCGGCCGCGTATTTGTTGAAATCTTCGAT
GAAGAGTCAAAGAAATGCGTTAACGCTAAATGGCTAGCTCAAGGCACTATCTATCCAGATGTGATTGAGTCTGCAGGTAG
CGCAACCGGCAAGGCACATTGCATTAAGTCTCACCATAACGTTGGCGGTTTGCCTGATGATATGGAAATGGGTCTGGTTG
AGCCATTACGTGAACTATTTAAAGATGAAGTACGTAAGATAGGTCTAGAGTTAGGCCTTCCATACAATATGCTTTATCGT
CATCCGTTCCCAGGACCAGGTCTTGGTGTACGTGTACTTGGCGAAGTAAAGAAAGAGTACTGTGACTTGCTACGTTTAGC
CGATGCGATTTTTATCGAAGAGCTACATAAAGCCGACCTTTATAACAAGGTTAGCCAAGCATTTACCGTGTTCCTACCAG
TACGCTCTGTTGGCGTAATGGGCGATGGTCGTAAGTACGACTGGGTTGTATCACTACGTGCAGTTGAAACTATCGACTTT
ATGACAGCGCATTGGGCACACCTACCTTATGATTTCCTAGGTCGTGTATCTAACCGTATCATTAATGAAGTAAACGGTAT
TTCTCGTGTAGTTTACGATATTTCAGGTAAGCCACCAGCAACGATTGAATGGGAATAA

Protein sequence :
MSNIHEHKILILDFGSQYTQLIARRIREIGVYCELWAWDVSEEQIREFAPNGIILAGGPESVTAENSPRAPEYVFNAGVP
VLGICYGMQTMSEQLGGKVIQGVGEGEFGYAQVEVQTESALFKAIEDAVSETGKPLLDVWMSHGDKVSAIPEGFVAVAKT
ETCPFAAMANEDKQFYGVQFHPEVTHTRQGKRMLEHFALEICACAANWKPASIIEDAIERLKAQIGDDEVILGLSGGVDS
SVVAMLLHRAIGDKLTCVFVDNGLLRLNEAEQVMEMFGDHFGLNIVHVDAENRFLDAMAGEAEPEAKRKIIGRVFVEIFD
EESKKCVNAKWLAQGTIYPDVIESAGSATGKAHCIKSHHNVGGLPDDMEMGLVEPLRELFKDEVRKIGLELGLPYNMLYR
HPFPGPGLGVRVLGEVKKEYCDLLRLADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 6e-125 51
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-125 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-125 51
guaA NP_938969.1 GMP synthase Not tested Not named Protein 6e-111 49