Gene Information

Name : lysS (Teth39_0318)
Accession : YP_001664323.1
Strain : Thermoanaerobacter pseudethanolicus ATCC 33223
Genome accession: NC_010321
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 358226 - 359725 bp
Length : 1500 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCTAATTCAAATGATAACATTTGGAACAACACTGAAGAACTCAATGAACTTTTGCGAATAAGAAGAGAAAAATTAAA
TATTTTAAGAAGCATGGGAATAGAACCTTACGGTATTGACAGGTTTGAAAGGACTAATTTGTCCTCTGATATTAAAAACG
ATTACGAGAATTTTGAAGGCAAAGTGGTTACTTTAGCAGGCAGAATTATGTCTAAAAGGAGCCATGGAAAAGCTTCTTTT
GCTGATATTCAAGACAGAGATGGAAGAATCCAGATTTATGTCAAGTATGACACAGTAGGGGAAAAGAACTACGAAATTTT
TAAAATCTTAGATATTGGAGATATAATAGGTGTTACAGGAGAGGTTTTTAAATCTAAAACTGGAGAAATAACTATTCGCG
TGACAGATTTTAAACTTTTGTCTAAGTCTCTTCAAATACTGCCAGAAAAATGGCATGGTTTAAAAGACCCTGATTTGCGT
TATCGGCAGAGATATACAGATTTAATAATAAATCCCGAAGTAAAAGAGGTGTTTTTAAAGAGGACGAAAATAATAAAGGC
GATAAGAGAGTTTCTTGACAATAGAGGATTTTTAGAGGTGGAGACTCCTATTCTTCATACTATTGCGGGTGGGGCTGCAG
CAAGGCCTTTTATTACTCATCACAATGCTTTAGACATTGATATGTACTTGCGAATTGCTTTAGAGCTTCATTTAAAAAGA
CTTATTGTGGGTGGACTTGAAAAAGTATATGAAATGGGCAGAGTTTTTAGAAATGAAGGAATGGATATAAGGCACAATCC
GGAATTTACTCTTTTAGAGCTTTATGAAGCCTATACTGATTATTACGGTATGATGGAACTTACAGAACAATTATTCGCCT
ATGTGGCCCAAAAGGTTAATGGTATTACGAAAATAGTTTATCAAGGGACAGAAATAGATTTGACACCTCCTTGGAAGAGA
ATTACTATGGTGGATGCGATAAAAGAATATGTAGGGGTAGACTTTAATGAAGTGAAGACAGATGAAGAGGCAATAGAGAT
AGCGAAGAAATTAAACCTTGAGACAAAAGAAGGAATGAAAAAGGGAGAAGTAATAGCACTTGTTTTTGACGAGCTAGTAG
AACAGCATTTGATACAGCCAACTTTTGTTATGGATTATCCTGTAGAGATTTCTCCTTTAGCTAAGAGAAAACATGACAAT
CCAGCATTTACTTCTAGATTTGAAGCTTTTATTTACGGAAGAGAAGTGGCTAATGCCTTTTCAGAATTAAATGACCCTAT
AGACCAAAAAGAAAGGTTTTTAGAACAATTAAAACAAAGAGAAGCCGGCGACGAAGAAGCTCATATGATGGATGAGGATT
TTATAAATGCTCTTGAGGTTGGTATGCCACCGACTGGAGGACTAGGTATAGGGGTAGACAGACTTGTGATGTTTATGACA
GATGCTTATTCTATAAGAGATGTAATATTATTCCCGACGATGAAGCCTAAAAATGACTAA

Protein sequence :
MSNSNDNIWNNTEELNELLRIRREKLNILRSMGIEPYGIDRFERTNLSSDIKNDYENFEGKVVTLAGRIMSKRSHGKASF
ADIQDRDGRIQIYVKYDTVGEKNYEIFKILDIGDIIGVTGEVFKSKTGEITIRVTDFKLLSKSLQILPEKWHGLKDPDLR
YRQRYTDLIINPEVKEVFLKRTKIIKAIREFLDNRGFLEVETPILHTIAGGAAARPFITHHNALDIDMYLRIALELHLKR
LIVGGLEKVYEMGRVFRNEGMDIRHNPEFTLLELYEAYTDYYGMMELTEQLFAYVAQKVNGITKIVYQGTEIDLTPPWKR
ITMVDAIKEYVGVDFNEVKTDEEAIEIAKKLNLETKEGMKKGEVIALVFDELVEQHLIQPTFVMDYPVEISPLAKRKHDN
PAFTSRFEAFIYGREVANAFSELNDPIDQKERFLEQLKQREAGDEEAHMMDEDFINALEVGMPPTGGLGIGVDRLVMFMT
DAYSIRDVILFPTMKPKND

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 4e-112 52
lysS YP_005163386.1 lysyl-tRNA synthetase Not tested Not named Protein 8e-84 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001664323.1 lysyl-tRNA synthetase VFG1668 Protein 2e-112 52