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Name : leuS (Teth39_1956) Accession : YP_001665923.1 Strain : Thermoanaerobacter pseudethanolicus ATCC 33223 Genome accession: NC_010321 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 2009492 - 2011942 bp Length : 2451 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGGCGTATTCGGTTGAAATTGATAGAAAATGGCAAAAAAGATGGGAAGAGACAAAACTTTATAAGTTTAATCCTAAAAA TGTAGATAAAAAGCTTTATTGCCTTGAGATGTTTTCTTATCCTTCAGGTGCCAAGCTTCACGTAGGACATTGGTACAATT ATGGACCTACTGATTCTTGGGCGAGAATGAAAAGAATGCAAGGATGGGAAGTTTTTCATCCAATGGGATTTGACGCTTTT GGACTTCCTGCAGAAAACTATGCCATAAAGACGGGAATACATCCTTATGATTCCACCATGGAAAATATAAGGACGATGGA AAAGCAGCTTAAAGAAATGGGGGCGACTTTTGATTGGGACTATGAAGTAATAACTTGCTTACCGGAATACTACAAATGGA CGCAGTGGATTTTCTTGAAGCTTTTTGAGGCAGGCCTTGCCTATAGAAAAAAAGCGCCAGTGAATTGGTGTCCCAGTTGT CAAACTGTTCTTGCAAACGAACAAGTTATAGATGGGAAATGTGAAAGGTGCGGCACTGAAGTTACAAAGAAAGATTTGAC TCAGTGGTTTTTTAAGATAACTGCTTATGCAGAAGAACTCCTTGAAAAACTGGATGAACTTGATTGGCCTGAGAAGACAA AAATAATGCAGAGAAATTGGATTGGAAAGTCGGATGGAGCAGAGATAGAATTTAAAGTAGCCGGAAAAGACCTGACATTT AAGGTATTTACTACAAGAGCTGACACGTTGTATGGAGCGACGTATGTAGTTATTGCGCCAGAACACGAAATTGTAGATTT AATTACTACAGAAGAATATAAACAAGCTGTTGAAGAGTATAAAGAATACGCGAGAAAACAGAGTGAGATTGAAAGGTTGT CTACTGAAAAAGAAAAGACAGGGGTATTTACAGGAGCATACGCAATTCATCCTCTGACGGGAGAGAAACTCCCTATTTGG ATAGCAGACTATGTCCTTGCAACATATGGAACAGGATGTGTCATGGCTGTTCCTGCCCATGATAAAAGAGATTATGAGTT TGCAACAAAATACAACCTTCCTATAAAAAGAGTGATAAAAGGAATTGGAGATGTGGAGGACAGTCTACCCTTTGATGAGT ATGGAGTGCTTGTAGACAGTGGAGAATTTGCAGGTTTGAAATCAGAAGAAGCGAGGATAAAAATTGTAGAAAAATTAAAA CAAGAAGGTAGAGCAGAGTTTAAAGTAAATTACAGATTGAGGGATTGGCTTGTTTCAAGGCAGAGATACTGGGGCGCTCC AATACCTGTTATTCACTGTGAACGCTGTGGCATAGTCCCTGTCCCAGAAGAAGATTTACCAGTGTTACTCCCTTATGATG TGGAATTTGCTCCAACAGGTGAATCTCCACTTAAAAAGCATGAAGGCTTTATGAACGTTACTTGTCCCAAATGTGGTGGC AAGGCTTTAAGAGACCCTGATACGTTGGACACTTTTGTGGATTCTTCGTGGTACTTTTTGAGATATCCCGATAACAAAAA CGACAAAGAGCCTTTCAATAAAGAATGGATAAATAAAATGTTGCCTGTTGACAAGTACGTAGGTGGAGCAGAGCACGCGA CAATGCATCTTTTGTACGCAAGGTTTGTTACAAAGGCTTTGAGAGACTTAGGATATCTTGACTTTGATGAGCCGTTTAAA TCTTTGGTGCATCAAGGCACAATATTGGGACCTGATGGCAGCAGAATGAGCAAATCTAAAGGGAATGTAATTTCGCCTGA CGAATACATTAAAGAATACGGTTCTGATGTATTTAGACTCTATCTGATGTTTGGATTTGCTTATTCTGAAGGTGGGCCAT GGAATGATGATGGAATAAAAGCCATTGCAAGGTTTGTCAACAGAGTGGAGAGATTTATAGATAAATTCATAGAGACAAGA AACAATCCTGGAAAAATAAAAGATGATATGGGGAAAGATGAAAAAGAGTTAAACTATGTGAGACATTATGCTATAAAAGG TGTGACAGAAGATGCAGAGAGATTTCAGTTTAATACTGCAATAGCGAGGATAATGGAACTGGTAAATGCCCTTTATAAAT ACGAGGCAGATGTGGAAGTTAAAAATATCAAATTTTATGAAGAAGTGGTGGCAGATTTAATAAAACTTTTGGCGCCATTT GCTCCTCACTTTTCTGAAGAAATGTGGGAAAAGCTTGGATATGAATATTCTGTCTTCAATCAGAAATGGCCTGAGTGGGA TGAAAAAGCTCTACAAAGAGATGTTGTAGAAATAGCTGTGCAGGTAAACGGCAAGGTAAGGGGGAGACTTGAAGTTCCTT CAAAAGCTACTGACGAAGAAATAGAAAAGCTCGCTCTTTCTGATAAAAATGTAAAAGCATATGTGGATGGAAAAGAGATA AAGAAGGTCATAGTTGTCAAAAACAGGCTTGTAAATATTGTTGTGAAATAA Protein sequence : MAYSVEIDRKWQKRWEETKLYKFNPKNVDKKLYCLEMFSYPSGAKLHVGHWYNYGPTDSWARMKRMQGWEVFHPMGFDAF GLPAENYAIKTGIHPYDSTMENIRTMEKQLKEMGATFDWDYEVITCLPEYYKWTQWIFLKLFEAGLAYRKKAPVNWCPSC QTVLANEQVIDGKCERCGTEVTKKDLTQWFFKITAYAEELLEKLDELDWPEKTKIMQRNWIGKSDGAEIEFKVAGKDLTF KVFTTRADTLYGATYVVIAPEHEIVDLITTEEYKQAVEEYKEYARKQSEIERLSTEKEKTGVFTGAYAIHPLTGEKLPIW IADYVLATYGTGCVMAVPAHDKRDYEFATKYNLPIKRVIKGIGDVEDSLPFDEYGVLVDSGEFAGLKSEEARIKIVEKLK QEGRAEFKVNYRLRDWLVSRQRYWGAPIPVIHCERCGIVPVPEEDLPVLLPYDVEFAPTGESPLKKHEGFMNVTCPKCGG KALRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYARFVTKALRDLGYLDFDEPFK SLVHQGTILGPDGSRMSKSKGNVISPDEYIKEYGSDVFRLYLMFGFAYSEGGPWNDDGIKAIARFVNRVERFIDKFIETR NNPGKIKDDMGKDEKELNYVRHYAIKGVTEDAERFQFNTAIARIMELVNALYKYEADVEVKNIKFYEEVVADLIKLLAPF APHFSEEMWEKLGYEYSVFNQKWPEWDEKALQRDVVEIAVQVNGKVRGRLEVPSKATDEEIEKLALSDKNVKAYVDGKEI KKVIVVKNRLVNIVVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 3e-154 | 45 |
