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Name : ddl (Teth39_0187) Accession : YP_001664196.1 Strain : Thermoanaerobacter pseudethanolicus ATCC 33223 Genome accession: NC_010321 Putative virulence/resistance : Resistance Product : D-alanyl-alanine synthetase A Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1181 EC number : - Position : 207497 - 208576 bp Length : 1080 bp Strand : + Note : D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli DNA sequence : ATGGAAAAGAAGAAAATAGCTGTTTTATTTGGCGGACAATCAGGAGAACATGAAGTTTCTTTAATGTCTGCAAAGTCTAT AATAAACAACCTTGATAAAGATAAATACGAGATTTACATGGTAGGTATTACAAAAAAAGGAGAATGGTATCTGTATAGAG GAGATGTGGGGAAAATAGAAACTGGAGAATGGGAAAAAGAAGGAATTCCTGCAATTATGGGAGCTTCTACAAAGTATAGA GGAATAATAACTTTCGAAGATGGAGAAAACGGTTTTTATCCTATAGACGTGGTATTTCCTGTTTTACATGGTCCTAATGG AGAAGATGGGACTATACAAGGGCTTTTAGAACTATTAGACATGCCTTATGTAGGTGCTAATGTGCTTTCTTCTGCTTTAT GCATGGATAAAGTTTTTACAAAAAGAATTTTTAAGGAAGCGGGGTTACCTACACCTGATTTTGTAGTAGTGTATGGAAAA GAGATTGAAGACTTAGAAGCTATAAAGAAAAAAATTGAACACTTAGGATATCCTTGTTTTGTAAAACCTGCTAATTTGGG GTCGAGTGTTGGCATTACTAAAGTCCACAACGAGGAAGAACTTCCTGGGGCCTTGAAATTAGCTGCGAAATATGATAGAA AATTATTAATAGAAAGAGGAATAGATGCCAGAGAGATTGAATGCTCTGTTTTGGGTAATGAAAATCCCGAGGCCTCTATT GCAGGAGAAATTGTTCCTTCTAATGAATTCTATGATTATAATGCTAAATATTTTGATGGGGGTAAATCTCTTCTCTTAAT ACCTGCACCACTTCCAGATGAAAAAATGGAAGAGGTAAGAAAGCTTGCTATAAAGGCCTACAAAGCTTTGGATTTGAGAG GTATGGCGAGAGTAGACTTTTTAATGGATAGAAATACAGGTACTCTTTATTTAAATGAAGTTAATACCATTCCGGGGTTT ACAAAAATAAGCATGTATCCCAAATTATGGGAATCAAGTGGAAAGTCTTATTCAACATTATTGGATGAGCTTATAAACTT AGCAGTAGAGAGCCATAATGAAAAATGTAGGGAATGGTGA Protein sequence : MEKKKIAVLFGGQSGEHEVSLMSAKSIINNLDKDKYEIYMVGITKKGEWYLYRGDVGKIETGEWEKEGIPAIMGASTKYR GIITFEDGENGFYPIDVVFPVLHGPNGEDGTIQGLLELLDMPYVGANVLSSALCMDKVFTKRIFKEAGLPTPDFVVVYGK EIEDLEAIKKKIEHLGYPCFVKPANLGSSVGITKVHNEEELPGALKLAAKYDRKLLIERGIDAREIECSVLGNENPEASI AGEIVPSNEFYDYNAKYFDGGKSLLLIPAPLPDEKMEEVRKLAIKAYKALDLRGMARVDFLMDRNTGTLYLNEVNTIPGF TKISMYPKLWESSGKSYSTLLDELINLAVESHNEKCREW |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanB | NP_815951.1 | D-alanine--D-lactate ligase | Not tested | Not named | Protein | 4e-56 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ddl | YP_001664196.1 | D-alanyl-alanine synthetase A | AF277571.gene.p01 | Protein | 5e-56 | 42 |
| ddl | YP_001664196.1 | D-alanyl-alanine synthetase A | AY489045.gene.p01 | Protein | 7e-56 | 42 |
| ddl | YP_001664196.1 | D-alanyl-alanine synthetase A | U00456.gene.p01 | Protein | 2e-56 | 41 |
| ddl | YP_001664196.1 | D-alanyl-alanine synthetase A | U35369.1.gene6.p01 | Protein | 2e-56 | 41 |
| ddl | YP_001664196.1 | D-alanyl-alanine synthetase A | AE016830.1.gene2250. | Protein | 2e-56 | 41 |
| ddl | YP_001664196.1 | D-alanyl-alanine synthetase A | AF130997.1.orf4.gene | Protein | 9e-54 | 41 |
