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Name : guaA (Teth39_1719) Accession : YP_001665692.1 Strain : Thermoanaerobacter pseudethanolicus ATCC 33223 Genome accession: NC_010321 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : - Position : 1757366 - 1758904 bp Length : 1539 bp Strand : - Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGGGGATTAAACGGGAAGTAGTGTTAGTTTTAGACTTTGGAGGCCAATACACACAATTAATTGCGAGAAGAATAAGAGA AGCAAATGTCTTTTGCGAGATTGTTCCTTACAATATTTCTCCAGAGGAGATACGAAAAAAAGAGCCAAAGGGAATTGTGC TTTCTGGAGGACCTGCCAGTGTATATGCAAAAAATGCTCCTAAATGCGATAAGGAAATTTTTGAGTTAGGCTATCCTGTA TTAGGTATATGTTATGGTGCACAACTTATGACAGAGCTTTTAGGCGGAAAAGTTGCGCCAGCACCTGTGAAGGAATATGG CAAGACAGAAATTGTCTTAAATAATACTATTCCTTTGTTTAAAGGGATAGAAAGAGACACTGTTGTTTGGATGAGCCATA CTGACCACATAGAACTTCCTCCTCCAGATTTTAAGGTAGTAGCCTCTACTGACAATTGTCCTATCGCAGCGATTGCGAAT GTAGAAAAGAAATTGTATGCGGTTCAATTCCATCCTGAAGTTTCACACACTCATAGAGGAACAGAGATTATAAGAAATTT CCTTTTTGAAGTATGTGATTGCGCGGCAGATTGGACAATGGATTCTTTGATTGAGCAGACAGTAAAGGAAATAAAAGCGA AAGTAGGAAAACACAAAGCTGTATGTGCTCTGTCTGGTGGTGTAGATTCTTCAGTGGCTGCTGTTTTAGTAGACAGAGCC ATTCACGACCAATTGGTGTGCATTTTTGTTGATACAGGGCTTTTAAGGAAAAACGAAGGAGATATGGTTATTGAAACTTT TAGAAAAAATTATGACATGAACATAATCCGGGTAGATGCAAAGGATAGATTTTTGTCACGACTTAAGGGAGTTACGGATC CAGAAGAAAAGAGAAAAATTATTGGTAATGTTTTTATAGAAGTTTTTAAAGAAGAAGCTTTAAAGATAGGAGATGTGAAA TTTTTGGTGCAGGGTACTTTGTATCCTGATGTAATAGAAAGTGGCAATGGCGTGTCTTCTACTATTAAAAGTCACCACAA TGTTGGAGGTTTGCCTGAAGATATAGGTTTTGAACTTATTGAACCTTTGAGGATGCTTTTTAAAGACGAAGTAAGGCAAG TAGGTAAAGAATTAGGAATCCCTGAGGAAATATTGTATAGGCAGCCTTTCCCTGGACCAGGCCTTGCAGTCAGAATTCTT GGAGAAGTTACAGAAGAAAAGTTAGAAATTTTGAGACAAGCTGACAGCATAGTTCTAAGAGAGATGAAAAAATTTGGATG GTATAATAAAGTGTGGCAGTCATTTGCTGTATTGCCTGGAATAAAGAGCGTTGGTGTTATGGGTGATGAAAGGACATACG CTTATGCGATAATTTTGAGGGTAGTAGATAGCTACGACGGGATGACGGCGGATTGGACAAAGCTTCCTTATGAAATTTTA GAAAGTATATCTACTAGCATTACTAATGAAGTTCCAGGAGTAAATCGAGTGCTTTACGACATTACTTCTAAACCTCCTGC TACCATAGAATGGGAATAA Protein sequence : MGIKREVVLVLDFGGQYTQLIARRIREANVFCEIVPYNISPEEIRKKEPKGIVLSGGPASVYAKNAPKCDKEIFELGYPV LGICYGAQLMTELLGGKVAPAPVKEYGKTEIVLNNTIPLFKGIERDTVVWMSHTDHIELPPPDFKVVASTDNCPIAAIAN VEKKLYAVQFHPEVSHTHRGTEIIRNFLFEVCDCAADWTMDSLIEQTVKEIKAKVGKHKAVCALSGGVDSSVAAVLVDRA IHDQLVCIFVDTGLLRKNEGDMVIETFRKNYDMNIIRVDAKDRFLSRLKGVTDPEEKRKIIGNVFIEVFKEEALKIGDVK FLVQGTLYPDVIESGNGVSSTIKSHHNVGGLPEDIGFELIEPLRMLFKDEVRQVGKELGIPEEILYRQPFPGPGLAVRIL GEVTEEKLEILRQADSIVLREMKKFGWYNKVWQSFAVLPGIKSVGVMGDERTYAYAIILRVVDSYDGMTADWTKLPYEIL ESISTSITNEVPGVNRVLYDITSKPPATIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-148 | 58 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-148 | 58 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 1e-148 | 58 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 1e-135 | 53 |
