Gene Information

Name : smpB (Teth39_1355)
Accession : YP_001665343.1
Strain : Thermoanaerobacter pseudethanolicus ATCC 33223
Genome accession: NC_010321
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1392919 - 1393389 bp
Length : 471 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
TTGGCGAAGGAAGAAATTAAAATAATCGCTCAAAACAAAAAAGCTTACCATGATTACTTCATTGAAGAAACTTATGAAGC
AGGAATAGTGCTTAGTGGAACTGAAGTTAAATCTATTAGGATGGGGAAAGTCAATTTAAAAGATAGCTTTGCAAGAGTTG
AAAACAACGAAGTTTATCTTTATAATATGCATATAAGTCCTTATGAAAAAGGCAATATATTTAATAAAGACCCCTTAAGG
ACTAGAAAATTACTTCTCAATAGACATGAGATTAATAAACTAATTGGTTATGTGACAAGGAAGGGTTACACTTTAATTCC
TACAAAGCTTTATTTAAAGCGAGGCCTTGTCAAAGTCGAATTAGCTGTAGCGAGAGGTAAAAAACTCTACGATAAGAGAG
AAGATATTGCGAGAAGAGATGCAAAAAGTGAATTAGAAAAACACTTTAAAGAAAAACAATTAGGCATATAA

Protein sequence :
MAKEEIKIIAQNKKAYHDYFIEETYEAGIVLSGTEVKSIRMGKVNLKDSFARVENNEVYLYNMHISPYEKGNIFNKDPLR
TRKLLLNRHEINKLIGYVTRKGYTLIPTKLYLKRGLVKVELAVARGKKLYDKREDIARRDAKSELEKHFKEKQLGI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 6e-35 58
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-29 50
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 3e-25 42