Gene Information

Name : guaA (Teth514_0515)
Accession : YP_001662159.1
Strain : Thermoanaerobacter sp. X514
Genome accession: NC_010320
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 530006 - 531544 bp
Length : 1539 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGGGATTAAACGGGAAGTAGTGTTAGTTTTAGACTTTGGAGGCCAATACACACAATTAATTGCGAGAAGAATAAGAGA
AGCAAATGTCTTTTGCGAGATTGTTCCTTACAATATTTCTCCAGAGGAGATACGAAAAAAAGAGCCAAAGGGAATTGTGC
TTTCTGGAGGACCTGCCAGTGTATATGCAAAAAATGCTCCTAAATGCGATAAGGAAATTTTTGAGTTAGGCTATCCTGTA
TTAGGTATATGTTATGGTGCACAACTTATGACAGAGCTTTTAGGCGGAAAAGTTGCGCCAGCACCTGTGAAGGAATATGG
CAAGACAGAAATTGTCTTAAATAATACTATTCCTTTGTTTAAAGGGATAGAAAGAGACACTGTTGTTTGGATGAGCCATA
CTGACCACATAGAACTTCCTCCTCCAGATTTTAAGGTAGTAGCCTCTACTGACAATTGTCCTATCGCAGCGATTGCGAAT
GTAGAAAAGAAATTGTATGCGGTTCAATTCCATCCTGAAGTTTCACACACTCATAGAGGAACAGAGATTATAAGAAATTT
CCTTTTTGAAGTATGTGATTGCGCGGCAGATTGGACAATGGATTCTTTGATTGAGCAGACAGTAAAGGAAATAAAAGCGA
AAGTAGGAAAACACAAAGCTGTATGTGCTCTGTCTGGTGGTGTAGATTCTTCAGTGGCTGCTGTTTTAGTAGACAGAGCC
ATTCACGACCAATTGGTGTGCATTTTTGTTGATACAGGGCTTTTAAGGAAAAACGAAGGAGATATGGTTATTGAAACTTT
TAGAAAAAATTATGACATGAACATAATCCGGGTAGATGCAAAGGATAGATTTTTGTCACGACTTAAGGGAGTTACGGATC
CAGAAGAAAAGAGAAAAATTATTGGTAATGTTTTTATAGAAGTTTTTAAAGAAGAAGCTTTAAAGATAGGAGATGTGAAA
TTTTTGGTGCAGGGTACTTTGTATCCTGATGTAATAGAAAGTGGCAATGGCGTGTCTTCTACTATTAAAAGTCACCACAA
TGTTGGAGGTTTGCCTGAAGATATAGGTTTTGAACTTATTGAACCTTTGAGGATGCTTTTTAAAGACGAAGTAAGGCAAG
TAGGTAAAGAATTAGGAATCCCTGAGGAAATATTGTATAGGCAGCCTTTCCCTGGACCAGGCCTTGCAGTCAGAATTCTT
GGAGAAGTTACAGAAGAAAAGTTAGAAATTTTGAGACAAGCTGACAGCATAGTTCTAAGAGAGATGAAAAAATTTGGATG
GTATAATAAAGTGTGGCAGTCATTTGCTGTATTGCCTGGAATAAAGAGCGTTGGTGTTATGGGTGATGAAAGGACATACG
CTTATGCGATAATTTTGAGGGTAGTAGATAGCTACGACGGGATGACGGCGGATTGGACAAAGCTTCCTTATGAAATTTTA
GAAAGTATATCTACTAGCATTACTAATGAAGTTCCAGGAGTAAATCGAGTGCTTTACGACATTACTTCTAAACCTCCTGC
TACCATAGAATGGGAATAA

Protein sequence :
MGIKREVVLVLDFGGQYTQLIARRIREANVFCEIVPYNISPEEIRKKEPKGIVLSGGPASVYAKNAPKCDKEIFELGYPV
LGICYGAQLMTELLGGKVAPAPVKEYGKTEIVLNNTIPLFKGIERDTVVWMSHTDHIELPPPDFKVVASTDNCPIAAIAN
VEKKLYAVQFHPEVSHTHRGTEIIRNFLFEVCDCAADWTMDSLIEQTVKEIKAKVGKHKAVCALSGGVDSSVAAVLVDRA
IHDQLVCIFVDTGLLRKNEGDMVIETFRKNYDMNIIRVDAKDRFLSRLKGVTDPEEKRKIIGNVFIEVFKEEALKIGDVK
FLVQGTLYPDVIESGNGVSSTIKSHHNVGGLPEDIGFELIEPLRMLFKDEVRQVGKELGIPEEILYRQPFPGPGLAVRIL
GEVTEEKLEILRQADSIVLREMKKFGWYNKVWQSFAVLPGIKSVGVMGDERTYAYAIILRVVDSYDGMTADWTKLPYEIL
ESISTSITNEVPGVNRVLYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-148 58
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-148 58
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-148 58
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-135 53