Gene Information

Name : leuS (Teth514_0255)
Accession : YP_001661908.1
Strain : Thermoanaerobacter sp. X514
Genome accession: NC_010320
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 269275 - 271725 bp
Length : 2451 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGGCTTACTCAGTGGATGTTGATAGAAAATGGCAAAAAAAATGGGAGGAGACAAAACTTTATAAGTTTAATCCTAAAAA
TGTAGATAAAAAGCTTTATTGCCTTGAGATGTTTTCTTATCCTTCAGGTGCCAAGCTTCACGTAGGGCATTGGTACAATT
ATGGACCTACTGATTCTTGGGCGCGTATGAAAAGAATGCAGGGATATGAAGTTTTTCATCCGATGGGATTTGACGCTTTT
GGACTTCCTGCAGAAAACTATGCTATAAAGACGGGAATACATCCTTATGATTCTACTATGGAAAATATAAGGACGATGGA
AAAGCAGCTTAAAGAAATGGGGGCGACTTTTGATTGGGACTATGAAGTAATAACTTGCTTACCGGAATACTACAAATGGA
CGCAGTGGATTTTCCTTAAACTTTTTGAGGCAGGCCTTGCCTATAGAAAAAAAGCTCCAGTAAATTGGTGTCCCAGTTGT
CAAACTGTTCTTGCAAACGAACAAGTTATAGATGGGAAATGTGAAAGGTGCGGCACTGAAGTTACAAAGAAAGATTTGAC
TCAGTGGTTTTTTAAGATAACTGCTTATGCAGAAGAACTCCTTGAAAAACTGGATGAACTTGATTGGCCTGAGAAGACAA
AAATAATGCAGAGAAATTGGATTGGAAAGTCGGATGGAGCAGAGATAGAATTTAAAGTAGCCGGAAAAGACCTGACATTT
AAGGTATTTACTACAAGAGCTGACACGCTATACGGAGCGACGTATGTAGTTATTGCGCCAGAACACGAAATTGTAGATTT
AATTACTACAGAAGAATATAAACAAGCTGTTGAAGAGTATAAAGAATACGCGAGAAAACAGAGTGAGATTGAAAGGTTGT
CTACTGAAAAAGAAAAGACAGGGGTATTTACAGGAGCATACGCAATTCATCCTCTGACGGGAGAGAAACTCCCTATTTGG
ATAGCAGACTATGTCCTTGCAACATATGGAACAGGATGTGTCATGGCTGTTCCTGCCCATGATGAAAGAGATTATGAGTT
TGCAACAAAATACAACCTTCCTATAAAAAGAGTGATAAAAGGAATAGGAGATATAGACGATAGTTTGCCTTTTGTCGAAT
ATGGAGAGCTTGTAGACAGTGGAGAATTTACAGGTTTGAAATCAGAAGAAGCGAGGATAAAAATTGTAGAAAAATTAAAG
CAAGAAGGTAGAGCAGAGTTTAAAGTAAATTACAGATTGAGGGATTGGCTTGTTTCAAGGCAGAGATACTGGGGTGCTCC
AATACCTGTCATTCACTGTGAACGGTGTGGCATAGTCCCTGTCCCAGAAGAAGATTTGCCAGTATTACTTCCTTATGATG
TGGAATTTGCTCCAACAGGTGAGTCTCCACTTAAAAAGCATGAGGGCTTTATGAATGTAACTTGTCCTAAATGTGGAGGT
AAAGCGTTAAGAGACCCCGATACTCTTGACACTTTTGTAGATTCTTCTTGGTACTTTTTAAGATATCCCGATAACAAAAA
CGACAAAGAGCCTTTCAATAAAGAATGGATAAATAAAATGTTGCCTGTTGACAAGTACGTAGGTGGAGCAGAGCATGCGA
CAATGCATCTTTTGTACGCAAGGTTTGTTACAAAGGCTTTGAGAGACTTAGGATATCTTGACTTTGATGAGCCGTTTAAA
TCATTAGTGCATCAAGGTACAATATTGGGCCCTGATGGAAGCAGAATGAGTAAATCTAAAGGAAATGTCATTTCGCCTGA
CGAATACATTAAAGAATACGGTTCTGATGTATTCAGACTCTATCTGATGTTTGGATTTGCTTATTCTGAAGGTGGGCCAT
GGAATGATGATGGTATTAAGGCAATTTCCAGATTTGTCAATAGAGTGGAGAGATTTATAGATAAATTCATAGAGACAAAA
AACAATCCTGGCAAGACTAAAGACGAAATGGGAAAAGATGAAAATGAATTAAACTATGTGAGACATTATGCTATAAAAAG
TGTGACAGAAGATGCAGAGAGATTTCAGTTTAATACTGCAATAGCGAGGATAATGGAACTGGTAAACGCTCTTTATAAAT
ACGACACAGATGTGGAAGTTAAAAATATCGAATTTTATGAAGATGTGGTGGCAGATTTAATAAGGCTTTTGGCGCCATTT
GCTCCTCACTTTTCCGAAGAAATGTGGGAAAAACTTGGATATGAATATTCTGTTTTCAATCAAAAATGGCCAAAGTGGGA
TGAAAAAGCTCTACAAAGAGATGTTGTAGAAATAGCTGTGCAGGTAAACGGCAAGGTAAGAGGAAGACTTGAAGTTCCTT
CAAATGCTCCTGACGAAGAAGTACAGAGGATTGCACTTTCAGATGATAAAATAAAATCCTACCTTGATGGAAAAGAAATA
AAGAAGGTCATAGTTGTTAAAGGCAGGCTTGTAAATATTGTTGTGAAATAA

Protein sequence :
MAYSVDVDRKWQKKWEETKLYKFNPKNVDKKLYCLEMFSYPSGAKLHVGHWYNYGPTDSWARMKRMQGYEVFHPMGFDAF
GLPAENYAIKTGIHPYDSTMENIRTMEKQLKEMGATFDWDYEVITCLPEYYKWTQWIFLKLFEAGLAYRKKAPVNWCPSC
QTVLANEQVIDGKCERCGTEVTKKDLTQWFFKITAYAEELLEKLDELDWPEKTKIMQRNWIGKSDGAEIEFKVAGKDLTF
KVFTTRADTLYGATYVVIAPEHEIVDLITTEEYKQAVEEYKEYARKQSEIERLSTEKEKTGVFTGAYAIHPLTGEKLPIW
IADYVLATYGTGCVMAVPAHDERDYEFATKYNLPIKRVIKGIGDIDDSLPFVEYGELVDSGEFTGLKSEEARIKIVEKLK
QEGRAEFKVNYRLRDWLVSRQRYWGAPIPVIHCERCGIVPVPEEDLPVLLPYDVEFAPTGESPLKKHEGFMNVTCPKCGG
KALRDPDTLDTFVDSSWYFLRYPDNKNDKEPFNKEWINKMLPVDKYVGGAEHATMHLLYARFVTKALRDLGYLDFDEPFK
SLVHQGTILGPDGSRMSKSKGNVISPDEYIKEYGSDVFRLYLMFGFAYSEGGPWNDDGIKAISRFVNRVERFIDKFIETK
NNPGKTKDEMGKDENELNYVRHYAIKSVTEDAERFQFNTAIARIMELVNALYKYDTDVEVKNIEFYEDVVADLIRLLAPF
APHFSEEMWEKLGYEYSVFNQKWPKWDEKALQRDVVEIAVQVNGKVRGRLEVPSNAPDEEVQRIALSDDKIKSYLDGKEI
KKVIVVKGRLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-153 45