Gene Information

Name : Teth514_1860 (Teth514_1860)
Accession : YP_001663476.1
Strain : Thermoanaerobacter sp. X514
Genome accession: NC_010320
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1876070 - 1877251 bp
Length : 1182 bp
Strand : +
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase

DNA sequence :
ATGGATTTAAGTTTTAAAACAAAAGTAGTACATACTGGAAACTACATAGATAAAGAAATTCCTCCAATGCCAAAAACTCT
TCCTATCTATCAAACTTCTGTTTTCACTTTTGATACGTTGGAAGAAGTTTACGATTATCTTGGTGGTAATCCTTCAAGGT
ATATGTACACAAGACTTGGAAACCCTAATCAAACTGCAGTGGAAGAATTAATTGCCAGTTTAGAAGGCGCGGAAGCAGGA
CAGGCTTGTTCATCCGGAATGGCGGCAATTTTTTCAGCTTTGTTGGCAGAAGTAAATTCAGGAGACCACATAATCGCCGC
AAAAGATATATACGGTGGTACAAACAGTCTTTTTAATGCAGAATTTAAAAGACTTAATATTGATGTAACTTTAGTGGATT
TCTCCGATTTAGAAGCTGTTGAAAAAGCTATAAAACCAAACACTAAAGTGATATACATGGAAATCATGACAAATCCTCTA
ATAAGAGTTTTTGATGTAGTAGAAGTTGCAAATATCGCAAAAAAGCACAATATAAAATTGATTGTTGACAATACTTTTAC
AACACCTTATTTGATAAAACCAATTGAATTAGGAGCTTATGCTGTAATACACAGCGCAACAAAATACATTAACGGCCACA
GCGATGTCATCGCCGGACTTATAGCAGGCAATAAAGAATTTATCTCTCGCACAAAAAGAATTACGCAAAACTTCGGCGGT
TCAATGAGCCCCTTTGACGCATGGCTGACTTTAAGAGGAGCAAAAACTCTATTCTTAAGAATGAGAGAACACTGTAAAAA
CGCAATGGAATTGGCTAAATTCTTAGAAAGCCATCCAAAAGTCAAAAAAGTGTATTATCCCGGACTTTCTTCTCACCCTG
ACTACAGTGTTTCAAAGAAGTTGTTTAAAGATGAGTTTGGAGGTATGTTAAGTTTTGAAATAGAAGGTGGAGAACCTGAA
GTAGATAAGTTTATGCAAGAGCTGAAACTGGTGAAATTTGCTCCTTCACTGGCAGGAGTACAAACCATGATAACTCATCC
AAAATCCACTTCCCATAGGTCTCTCAGCAAGGAAGAATTAAACGCGTTAGGAATTTCAGAAGGACTTATAAGAGTTTCTG
TTGGAATAGAGGAGATAGAAGATATTATAAAAGACTTTAAACAAGCTCTTGACAAGATATAA

Protein sequence :
MDLSFKTKVVHTGNYIDKEIPPMPKTLPIYQTSVFTFDTLEEVYDYLGGNPSRYMYTRLGNPNQTAVEELIASLEGAEAG
QACSSGMAAIFSALLAEVNSGDHIIAAKDIYGGTNSLFNAEFKRLNIDVTLVDFSDLEAVEKAIKPNTKVIYMEIMTNPL
IRVFDVVEVANIAKKHNIKLIVDNTFTTPYLIKPIELGAYAVIHSATKYINGHSDVIAGLIAGNKEFISRTKRITQNFGG
SMSPFDAWLTLRGAKTLFLRMREHCKNAMELAKFLESHPKVKKVYYPGLSSHPDYSVSKKLFKDEFGGMLSFEIEGGEPE
VDKFMQELKLVKFAPSLAGVQTMITHPKSTSHRSLSKEELNALGISEGLIRVSVGIEEIEDIIKDFKQALDKI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 1e-55 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Teth514_1860 YP_001663476.1 cystathionine gamma-synthase BAC0207 Protein 2e-63 42