Gene Information

Name : pykF (CTL0586)
Accession : YP_001654661.1
Strain : Chlamydia trachomatis 434/Bu
Genome accession: NC_010287
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 692793 - 694250 bp
Length : 1458 bp
Strand : +
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGATCGCTAGAACGAAAATTATTTGTACGATAGGCCCTGCAACGAATACCCCTGAGATGCTGGAAAAGCTTCTCGATGC
AGGGATGAATGTAGCTCGCCTTAATTTTAGCCACGGGACCCATGAAAGCCATGGCCGGACCATCGCTATTCTTAAAGAAC
TACGAGAGAAGCGCCAAGTTCCTTTAGCTATTATGCTAGATACAAAAGGTCCCGAAATTCGTTTAGGCCAAGTAGAATCT
CCTATAAAAGTACAGCCTGGGGATCGTCTTACTCTCGTTAGCAAAGAAATTTTAGGATCCAAAGAAAGCGGCGTTACTCT
TTATCCAAGTTGTGTATTCCCTTATGTTAGAGAACGAGCTCCTGTTCTCATTGATGATGGGTATATCCAAGCAGTGGTGG
TCAATGCTCAAGAGCATATGGTGGAAATAGAGTTTCAAAATTCAGGAGAAATAAAATCCAACAAATCTCTTAGCATCAAA
GATATCGATGTTGCTCTTCCTTTCATGACAGAGAAGGATATTGCAGACTTAAAATTTGGGGTAGAACAAGAACTCGATCT
TATCGCTGCTTCGTTCGTCAGATGTAATGAAGATATTGACAGCATGCGTAAAGTTTTGGAAAGCTTTGGTCGTCCTAATA
TGCCCATCATTGCCAAAATAGAAAATCATTTAGGAGTACAAAATTTCCAAGAGATCGCTAGAGCTGCTGATGGTATCATG
ATTGCACGCGGGGATCTTGGTATTGAATTGTCTATTGTTGAAGTTCCTGGACTACAAAAATTTATGGCCCGAGCATCGAG
GGAAACGGGTCGGTTTTGTATCACTGCAACGCAAATGCTCGAGTCAATGATTCGCAACCCCCTTCCTACACGAGCCGAAG
TCTCTGACGTTGCCAACGCCATTTACGATGGAACCTCTGCAGTCATGTTGTCTGGAGAAACTGCCTCAGGAGCCCATCCT
GTACATGCAGTAAAAACAATGCGTTCCATTATCCAAGAGACTGAGAAGACTTTCGATTACCACGCTTTTTTCCAGCTGAA
CGACAAAAACAGCGCTCTCAAAGTTTCTCCTTATCTTGAAGCCATTGGGTTTTCTGGAATCCAAATTGCAGAAAAAGCAT
CTGCCAAAGCCATTATTGTGTATACCCAGACGGGAGGATCTCCGATGTTTTTATCCAAATATCGACCTTATCTCCCTATT
ATTGCTGTTACCCCTAACCGCAATGTGTACTATCGTTTAGCTGTAGAATGGGGAGTATATCCTATGCTAACCCTGGAATC
GAACCGTACAGTCTGGCGTCACCAAGCTTGTGTATATGGAGTAGAAAAAGGAATTCTTTCTAACTATGATAAAATTCTTG
TCTTCAGCCGCGGAGCTGGGATGCAAGATACCAACAATCTCACCTTGACAACTGTGCATGATGCGCTATCCCCCTCTCTT
GACGAGATAGTTCCATAA

Protein sequence :
MIARTKIICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQVPLAIMLDTKGPEIRLGQVES
PIKVQPGDRLTLVSKEILGSKESGVTLYPSCVFPYVRERAPVLIDDGYIQAVVVNAQEHMVEIEFQNSGEIKSNKSLSIK
DIDVALPFMTEKDIADLKFGVEQELDLIAASFVRCNEDIDSMRKVLESFGRPNMPIIAKIENHLGVQNFQEIARAADGIM
IARGDLGIELSIVEVPGLQKFMARASRETGRFCITATQMLESMIRNPLPTRAEVSDVANAIYDGTSAVMLSGETASGAHP
VHAVKTMRSIIQETEKTFDYHAFFQLNDKNSALKVSPYLEAIGFSGIQIAEKASAKAIIVYTQTGGSPMFLSKYRPYLPI
IAVTPNRNVYYRLAVEWGVYPMLTLESNRTVWRHQACVYGVEKGILSNYDKILVFSRGAGMQDTNNLTLTTVHDALSPSL
DEIVP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 43
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 2e-63 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 6e-63 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_001654661.1 pyruvate kinase VFG0479 Protein 8e-64 43