Gene Information

Name : lysS (CTL0150)
Accession : YP_001654241.1
Strain : Chlamydia trachomatis 434/Bu
Genome accession: NC_010287
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 196047 - 197627 bp
Length : 1581 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCTGTAGAAGTTGAATACTTGCAACACGAAGATTATTTGTATAGAACAAGCAAGCTAAAGGAAATCAGAGATTTGGG
CATAAATCCTTACCCTTATCAATACACTGATTGTCTTGAAGTACAGGAAATTCGTAATCAGTTTGTAGATAACGAATTAG
GAGATAGCGAAGCGGCTTTTCGTAAAGAGACACCTAAGGTGCGTTTTGCCGGACGACTTGTTCTTTTCCGTTCTATGGGG
AAAAATGCTTTTGGGCAGATCCTCGATAATGATGCAAAGATTCAAGTGATGTTCAATCGAGATTTTTCTGCAGTGGCAGG
GTTAGCCGCGGATGCTGGGATTTCTCCGATTAAATTTATTGAGAAGAAACTTGATCTAGGAGACATCTTGGGTCTCGAAG
GGTATCTTTTCTTTACTCACTCAGGAGAATTAACGGTTCTCGTTGAAACGGTAACGTTGTTATGTAAATCCTTAATTTCT
TTGCCTGATAAGCATGCAGGATTAGCAGATAAAGAAATTCGCTATCGCAAACGTTGGGCAGATCTGATTTCCTCAGAGGA
TGTGCGTAAGACTTTCTTAACAAGAAGCCGGATTCTTAAGTTGATTCGTGAGTACATGGATCAGCAGAGCTTTTTAGAGG
TGGAAACTCCTATCTTGCAAACCGTCTACGGAGGAGCAGAAGCAACTCCTTTTGTTACCACGCTGCAAGCGCTACATGCA
GAAATGTTCCTAAGAATTTCTCTAGAGATTGCTTTGAAAAAACTCCTTGTTGGAGGAATGTCCCGAGTTTATGAAATCGG
CAAAGTTTTCCGTAACGAAGGAATCGATAGAACGCATAATCCAGAGTTTACCATGATAGAGGCTTATGCGGCTTATTGGG
ATTACAATGATGTAATGAAATGTGTGGAAAACCTTGTTGAGTATATCGTACGTGCTTTGAATAACGGGGAAACTCAGGTT
CAGTATTCACATTTAAAATCAGGACCTCAGGTTGTTGATTTTAAAGCTCCATGGATCCGTATGACGATGAAAGAAAGTAT
CTCTGTCTATGGCGGCGTCGATGTAGACTTACATGCAGATCATGAATTACGTAAAATTTTAGAAACACAAACATCTCTTC
CAGAGAAAACGTATGTTCATGCCTCACGAGGAGAGCTGATCGCTTTGCTATTTGATGAGCTGGTTTGTGATAAGCTCATC
GCTCCGCATCACATTACAGATCATCCATTAGAAACAACGCCACTTTGTAAAACATTGCGTTCTGGGGATGAAACTCTGGT
AGAACGATTTGAGAGTTTTTGTTTAGGAAAAGAGTTGTGTAATGCTTATTCGGAACTCAATGATCCTTTACAACAACGAA
AATTGTTGGAAGAGCAAATGCGTAAAAAGGCTTTAAATCCTGACAGCGAATACCATCCTATAGATGAAGAATTTCTAGAA
GCTCTTTGCCAAGGAATGCCTCCTGCAGGAGGATTTGGAATAGGTATCGATCGATTGGTTATGATGTTGACAGACGCTGC
ATCCATTCGGGATGTCCTGTTTTTCCCTGTTATGCGGCGTATAGAAGCAAAAAAAGATTAA

Protein sequence :
MSVEVEYLQHEDYLYRTSKLKEIRDLGINPYPYQYTDCLEVQEIRNQFVDNELGDSEAAFRKETPKVRFAGRLVLFRSMG
KNAFGQILDNDAKIQVMFNRDFSAVAGLAADAGISPIKFIEKKLDLGDILGLEGYLFFTHSGELTVLVETVTLLCKSLIS
LPDKHAGLADKEIRYRKRWADLISSEDVRKTFLTRSRILKLIREYMDQQSFLEVETPILQTVYGGAEATPFVTTLQALHA
EMFLRISLEIALKKLLVGGMSRVYEIGKVFRNEGIDRTHNPEFTMIEAYAAYWDYNDVMKCVENLVEYIVRALNNGETQV
QYSHLKSGPQVVDFKAPWIRMTMKESISVYGGVDVDLHADHELRKILETQTSLPEKTYVHASRGELIALLFDELVCDKLI
APHHITDHPLETTPLCKTLRSGDETLVERFESFCLGKELCNAYSELNDPLQQRKLLEEQMRKKALNPDSEYHPIDEEFLE
ALCQGMPPAGGFGIGIDRLVMMLTDAASIRDVLFFPVMRRIEAKKD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-69 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001654241.1 lysyl-tRNA synthetase VFG1668 Protein 1e-69 41