Gene Information

Name : kdsB (APJL_0085)
Accession : YP_001651135.1
Strain : Actinobacillus pleuropneumoniae JL03
Genome accession: NC_010278
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 92059 - 92811 bp
Length : 753 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAATTTTACTGTGATTATTCCGGCTCGTTACGCTTCAAGCCGCTTACCTCGTAAACCGTTGTTAGATATTGCCGGTAA
ACCGATGATTCAACACGTGTGGGAAAAGGCGCAACAAGCCGGTGCAACACGTGTGATTATTGCGACTGATCATCCGGAGA
TTGAAGCAACCGCCAAAGCGTTTGGCGCGGAAGTGTGCATGACTTCGGATCAACATAATTCAGGCACGGAACGTTTAGCG
GAAGTGATTGAAAAGATGCAGATTGCCGATAATGAAATTATCGTGAATGTACAAGGTGATGAGCCGCTGATCCCGCCGGT
GATCGTCTCGCAAGTGGCGGAAAATTTAGATCGTTGCCAAGTGAATATGGCGACATTAGCGGTAAAATTAACCACCAAAG
AAGAACTTTTCAATCCGAATGCCGTCAAAGCGCTGGCGGATAAAAACGGTATGGCACTCTATTTCTCTCGTGCGCCGATT
CCGTTTGCCCGTGATCATTTCGCAGACTGTGATGACGCTTTTGTCGCAAGCCAAAATTACTTACGCCATATTGGTATCTA
CGCATATCGTGCCGGCTTTGTGAAACAATACGTCGCTTGGCAGCCGACCCAATTAGAACAATTGGAATCGTTAGAGCAAC
TACGTGCGTTATGGTACGGAGAAAAAATTCATATCGAACTTGCTAAACAGGCACCTCAAGTGGGAGTGGATACGCAAGAA
GATTTGGAACGTGTTCGCCGAATTCTGGCTTAG

Protein sequence :
MNFTVIIPARYASSRLPRKPLLDIAGKPMIQHVWEKAQQAGATRVIIATDHPEIEATAKAFGAEVCMTSDQHNSGTERLA
EVIEKMQIADNEIIVNVQGDEPLIPPVIVSQVAENLDRCQVNMATLAVKLTTKEELFNPNAVKALADKNGMALYFSRAPI
PFARDHFADCDDAFVASQNYLRHIGIYAYRAGFVKQYVAWQPTQLEQLESLEQLRALWYGEKIHIELAKQAPQVGVDTQE
DLERVRRILA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-36 44
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-35 43
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-35 43