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Name : leuS (APJL_0884) Accession : YP_001651886.1 Strain : Actinobacillus pleuropneumoniae JL03 Genome accession: NC_010278 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 977484 - 980069 bp Length : 2586 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAACAACAATATAACCCAAGTGCAATTGAACCTAAAGTTCAGCAATTCTGGGCAGAAAATAAAGTTTTTAAAGCGGT TAAAGATGTAACAAAAGAGAAATACTATTGCCTTTCAATGTTGCCGTATCCGTCCGGTAAATTACATATGGGTCACGTAC GTAACTATACAATCGGTGATGTGGTTTCTCGTTATCAACGTATGATTGGTAAAAACGTGTTACAGCCGATGGGTTGGGAT GCTTTCGGTTTACCGGCGGAAGGTGCGGCGGTAAAAAATAACACGGCGCCGGCAAAATGGACGTACGAAAATATCGAATA TATGAAAGGTCAGCTCAAAATGTTGGGCTTTTCTTATGACTGGGATCGAGAAGTCACCACTTGCCGTCCGGAATACTACA AATGGGAACAATGGTTCTTCACCGAACTTTACAAAAAAGGGTTAGTGTATAAAAAAACCTCAACGGTAAACTGGTGTCCG AACGATGCGACTGTGCTTGCAAACGAACAGGTGCACGAAGGTTGTTGTTGGCGTTGTGATACGCCGGTAGAACAACGTGA GATTCCTCAATGGTTTATCAAAATTACCGACTATGCCGAAGAGTTATTAACTCACTTAGATAATCTTCCGCAATGGCCTG ATCAAGTAAAAACCATGCAACGTAACTGGATCGGTCGTTCTGAAGGGGTTGAAATCACCTTCAAAATCGCCGGTTCAAAT GCGGAATTACCGGTTTACACCACTCGTCCGGATACCTTCTTCGGTGTGAGCTATGTTGCGATTGCCGCTGCTCATCCATT AGCGGAAATGGCGGCAGAAAACAATCCTGCACTTGCAGAATTTATTCGTGAGGCGAAAAACACCAAAGTTGCAGAAGCAG AATTAGCAACAATGGAGAAAAAAGGGATGGCAACCGGCTTGTTCGCTATCCACCCGCTAACAGGTAAAGAAGTACCGGTT TGGGTTGCTAACTTCGTATTAATGCACTACGGTACAGGAGCAGTAATGGCTGTGCCGGCACACGATGAACGTGACTTTGA ATTTGCTCAAAAATACGGTTTGCAAATTAATCAAGTAATTCAACCGCTTGACGGTTCCGAATGGGATTTCTCAAAAGCCG CTTATACCGAGCACGGTAAATTGATTAATTCGGCTGAATTTGACGATTTAAATTTTGAGCAAGCATTCAATGCGATTGCC GATAAATTAGAATCGATGAAAGTGGGTAAACGCCAAGTAAACTTCCGTCTGCGTGACTGGGGGGTATCTCGTCAGCGTTA CTGGGGTGCGCCAATCCCAATGATGACGACCGAAGACGGCGAAGTAGTAACAGTGCCTATGCAAGATTTACCGGTCATTC TACCTGAAGATGTGGTAATGAACGGCGTACAAAGCCCGATCAAAGCTGATCCTGAGTGGGCGAAAACCACTTACAACGGC AAACCTGCGTTAAAAGAAACCGATACGTTCGATACCTTTATGGAATCGTCTTGGTACTATGCACGCTATACTTGCCCGCA ATATCACGAAGGTATGTTAGATTCTGACGAGGCAAACTACTGGTTACCAGTCGATCAATATATCGGCGGTATCGAACACG CAACCATGCACTTGCTCTATTTCCGCTTCTTCCACAAATTGTTACGTGATGCGGGTATTTTGAACTCTGACGAACCGGCA ACTAAACTTTTATGTCAAGGTATGGTGCTTGCTGATGCGTTCTATTACACCAGCCCGACTAACGAGCGTATTTGGGTTAG CCCGACACAAGTCACGCTTGAGCGTGATGAGAAAGGTCGCATCATCAAAGCGACTGATCCGGAAGGCCGTGAATTAGTTC ACAGCGGTATGACCAAAATGTCGAAATCGAAAAATAACGGCATCGACCCGCAAGAAATGGTGGAAAAATACGGTGCGGAC ACAGTACGTTTATTTATGATGTTCGCTTCACCGGCAGAAATGACGCTTGAATGGCAAGAATCCGGTGTGGAAGGTGCAAA ACGCTTCTTAGGTCGTGTGTGGAATTTAGTGTATGAATATAGCCAAAATCCTGCGACAGCAGCATTAGATGTAGCCGCAT TAAGCAAAGCACAAAAAGAACTTCGCCGTGACGTACACAAAACCATTGCGAAAGTGTCTGACGATATCGGTCGCCGTCAA ACATTCAATACCGCAATCGCGGCGATTATGGAATTAATGAACAAGCTGACGAAAGCACCACTTGAAAACGAACAAGACAA AGCGGTAATGGCGGAAGCATTAAGTGCGGTTGTACGTATGCTTTACCCAATTACGCCACATATCTGTTTCGAATTATGGC AAGCGCTAGGTAATAACGATACGATTGACTTTGCGCCATGGGTAGTTGCAGATGAGTCAGCAATGGTTGAAGACGAAAAA TTAGTTGTGGTACAAGTAAACGGTAAAGTTCGTGGTAAAGTTACCGTTTCGGCAACAGCAACCGAAGATGAAGTCAAAGC AATTGCGAAAGCGGATGCAAACGTAGCGAAATTCTTAGAAGGCGTAGAAATCGTGAAAGAAATCTATGTACCGTATAAGA TGTTAAGTTTTGCGGTAAAAGCCTAA Protein sequence : MQQQYNPSAIEPKVQQFWAENKVFKAVKDVTKEKYYCLSMLPYPSGKLHMGHVRNYTIGDVVSRYQRMIGKNVLQPMGWD AFGLPAEGAAVKNNTAPAKWTYENIEYMKGQLKMLGFSYDWDREVTTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP NDATVLANEQVHEGCCWRCDTPVEQREIPQWFIKITDYAEELLTHLDNLPQWPDQVKTMQRNWIGRSEGVEITFKIAGSN AELPVYTTRPDTFFGVSYVAIAAAHPLAEMAAENNPALAEFIREAKNTKVAEAELATMEKKGMATGLFAIHPLTGKEVPV WVANFVLMHYGTGAVMAVPAHDERDFEFAQKYGLQINQVIQPLDGSEWDFSKAAYTEHGKLINSAEFDDLNFEQAFNAIA DKLESMKVGKRQVNFRLRDWGVSRQRYWGAPIPMMTTEDGEVVTVPMQDLPVILPEDVVMNGVQSPIKADPEWAKTTYNG KPALKETDTFDTFMESSWYYARYTCPQYHEGMLDSDEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGILNSDEPA TKLLCQGMVLADAFYYTSPTNERIWVSPTQVTLERDEKGRIIKATDPEGRELVHSGMTKMSKSKNNGIDPQEMVEKYGAD TVRLFMMFASPAEMTLEWQESGVEGAKRFLGRVWNLVYEYSQNPATAALDVAALSKAQKELRRDVHKTIAKVSDDIGRRQ TFNTAIAAIMELMNKLTKAPLENEQDKAVMAEALSAVVRMLYPITPHICFELWQALGNNDTIDFAPWVVADESAMVEDEK LVVVQVNGKVRGKVTVSATATEDEVKAIAKADANVAKFLEGVEIVKEIYVPYKMLSFAVKA |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 1e-155 | 42 |
