Gene Information

Name : aldA (APJL_2061)
Accession : YP_001653050.1
Strain : Actinobacillus pleuropneumoniae JL03
Genome accession: NC_010278
Putative virulence/resistance : Virulence
Product : putative aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : -
Position : 2203205 - 2204686 bp
Length : 1482 bp
Strand : -
Note : -

DNA sequence :
ATGAAAGATCTTAACGTTTTCGATAAAAATTACGGCTTATTAATCAATGGCAAATGGACTCAAGGCAGCGGTAACGATTT
ACTTCCTTCTTACAATCCGGCGAACGGTGAAGTATTAGCGCATTTTGTCGATGCGACCGATGCGGATGTGGATGCGGCGG
TGAAAGCGGCACAAGAAGCATTTAAATCTTGGCGTAAAACGACAGTAGCGGAACGTGCGGCGATTTTAAATAAAATCGCC
GACGTGATTGATGAAAACAGTGAATTATTTGCATTGCAGGAAACCTTGGACAACGGTAAACCGATTCGTGAAACCAGAGC
GGCGGATATTCCGTTGGCTTCCGATCACTTCCGTTATTTCGCCAGTGCGATTCGTGCCGGCGAAGGCAGCTTAAATCAAA
TCAATCAAGAAGAACTTTCACTTGTTCTACGTGAGCCTATCGGCGTAGTCGGACAAATTATTCCGTGGAACTTCCCGTTC
TTAATGGCGGCATGGAAAATCGCACCGGCATTGGCGGCAGGTTGTACCGTAGTAATCCACCCTTCCAGCACCACTTCGTT
AAGCTTATTGTCTTTTGCACAAAAAATTAATCATTTACTACCGAAAGGCGTACTAAACGTAATTACCGGTAAAGGTTCAA
AATCCGGCGAATATATGTTACATCACAAAGGCTTCAATAAATTAGCCTTTACCGGTTCAACTGAAATCGGTCGTCATATT
GCGATTTCCGCCGCGGAATTACTCATTCCGGCAACCTTAGAATTAGGCGGTAAATCGGCTAATATTTTCTTTGACGATAT
GCCGTTTGATAAAGCGTTGGAAGGTGCGCAAAAAGGTATTTTATTCAACCAAGGACAAGTATGTTGCGCCGGTTCTCGTA
TCTTCGTACAAGAAGGGATTTACGACAAATTTGTGGCGGCACTCGCCGAAGAATTTAAGAAAGTCAAAGTCGGTTTACCA
TGGGAAGACGATACGCAAATGGGTGCACAGGTCAATGCGGGACAACTTAACACTATCTTAAAATATGTGAAAATCGGTGA
AGAAGAAGGTTGTCGTATTATTACCGGCGGTAGAAAAGTCTTGGCGGATAACCTTGCTTGCGGTGAATTCGTCGAACCGA
CCTTAATCGAGTCTAAAGATAATACCAGTCGTGTTGCACAAGAAGAAATCTTCGGACCGGTGGCAACCGTGATTAAATTC
AAAACCGAAGAAGACGTTATCCGTATGGCGAACGATTCGGAATACGGCTTAGGCGGCGGTGTTTGGACCAAAGACATCAA
CCGCGCGTTACGTGTTTCACAAGCAATCGAAACCGGTCGTGTTTGGGTAAACTGCTATAATATTCTACCGGCGGGCGCAC
CGTTCGGCGGTTATAAATCTTCCGGTATCGGACGTGAAACCCACCAAATGATGTTGGATGCTTACACCCAAGTGAAAAAT
ATCTACATCAGTACCCGTGAAGAACGTGAAGGAATGTATTAA

Protein sequence :
MKDLNVFDKNYGLLINGKWTQGSGNDLLPSYNPANGEVLAHFVDATDADVDAAVKAAQEAFKSWRKTTVAERAAILNKIA
DVIDENSELFALQETLDNGKPIRETRAADIPLASDHFRYFASAIRAGEGSLNQINQEELSLVLREPIGVVGQIIPWNFPF
LMAAWKIAPALAAGCTVVIHPSSTTSLSLLSFAQKINHLLPKGVLNVITGKGSKSGEYMLHHKGFNKLAFTGSTEIGRHI
AISAAELLIPATLELGGKSANIFFDDMPFDKALEGAQKGILFNQGQVCCAGSRIFVQEGIYDKFVAALAEEFKKVKVGLP
WEDDTQMGAQVNAGQLNTILKYVKIGEEEGCRIITGGRKVLADNLACGEFVEPTLIESKDNTSRVAQEEIFGPVATVIKF
KTEEDVIRMANDSEYGLGGGVWTKDINRALRVSQAIETGRVWVNCYNILPAGAPFGGYKSSGIGRETHQMMLDAYTQVKN
IYISTREEREGMY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-97 52
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-100 49
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-100 49
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-100 49
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 5e-100 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aldA YP_001653050.1 putative aldehyde dehydrogenase VFG0082 Protein 5e-98 52