Gene Information

Name : APJL_1788 (APJL_1788)
Accession : YP_001652782.1
Strain : Actinobacillus pleuropneumoniae JL03
Genome accession: NC_010278
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine kinase
Function : -
COG functional category : K : Transcription
COG ID : COG1940
EC number : -
Position : 1951630 - 1952502 bp
Length : 873 bp
Strand : +
Note : catalyzes the phosphorylation of the N-acetylmannosamine (ManNAc) liberated from N-acetyl-neuraminic acid by the nanA protein

DNA sequence : 
ATGCGTTGTTTAGCATTAGATATCGGCGGTACTAAGATTGCCTCGGCATTAGTCGAAAACGGAGTGATTTCCCAACGCCG
ACAAATCGGCACACCGCAACAAGATGCGGCGGAAGCAATGCATCAAACGTTGGCGGACATTTTGCAACAGTACCAAGGGC
AGTTTGATGCGGTATCGGTAGCTTCGACCGGTATTATCAATAACGGCGTTTTAACCGCATTAAACCCGAAGAATTTAGGC
GGGTTGGCTTTTTTCCCGTTGCAAGAAAGTATTGCACGTCATACCGATAAACCGATTTTCTTACTCAATGACGTACAAGC
GGCGGCTTGTGCCGAATATCAACATCAAGATAAACAAGCGGTCGAAAATTTCGTATTTATTACCGTTTCAACCGGGGTTG
GCGGCGGCATTATCCAAAATGGCAAATTGCTAACCCAACCGAATGGCGTAGCAGGACATATCGGGCATACTTTAGCGGAT
CCGAACGGGCCAATTTGTGGCTGTGGTCGCCGAGGTTGTGTGGAAGCGATTGCTTCCGGGCGAGCTATCGAAGCGGTTTC
AAGCCGATGGACGGAACCTTGTACACCGAAACAAGTGTTTGAGCAATTCCGAGCGGGCAAAGTGCAAGCGGTCGAATTAG
TCGAAAAATCTGCAAAAGCCATTGCCAATTTAGTGGCGGATTTAACCATCGGTTTAGATACGCAAAAAGTGGTGATCGGC
GGCAGTGTCGGCTTGGCGAAAGGTTATTTACCGCTCGTGCAAAAATATTTAGCCGAAATGCCGCATTTCTACCGTTGTGA
ATTGGAAGCGGCAAAATATGGCGGCAATGCCGGTTTAATCGGCGCGGCTGCATGGGCGGAACAACATTTTTAA

Protein sequence : 
MRCLALDIGGTKIASALVENGVISQRRQIGTPQQDAAEAMHQTLADILQQYQGQFDAVSVASTGIINNGVLTALNPKNLG
GLAFFPLQESIARHTDKPIFLLNDVQAAACAEYQHQDKQAVENFVFITVSTGVGGGIIQNGKLLTQPNGVAGHIGHTLAD
PNGPICGCGRRGCVEAIASGRAIEAVSSRWTEPCTPKQVFEQFRAGKVQAVELVEKSAKAIANLVADLTIGLDTQKVVIG
GSVGLAKGYLPLVQKYLAEMPHFYRCELEAAKYGGNAGLIGAAAWAEQHF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
nanK YP_002414055.1 N-acetylmannosamine kinase Not tested Not named Protein 5e-35 43
VC1782 NP_231417.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 9e-30 42
VC0395_A1379 YP_001217322.1 N-acetylmannosamine kinase Not tested VPI-2 Protein 9e-30 42
VPI2_0030 ACA01847.1 ROK family protein Not tested VPI-2 Protein 4e-29 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
APJL_1788 YP_001652782.1 N-acetylmannosamine kinase VFG1115 Protein 4e-30 42