Gene Information

Name : lipA2 (APJL_1727)
Accession : YP_001652723.1
Strain : Actinobacillus pleuropneumoniae JL03
Genome accession: NC_010278
Putative virulence/resistance : Virulence
Product : capsule polysaccharide modification protein
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3563
EC number : -
Position : 1885908 - 1887977 bp
Length : 2070 bp
Strand : +
Note : -

DNA sequence : 
GTGGCGCAATGTTCTATCACTAAATCGTTAATTTTCTCACGCGGAATTTTAAAGATCCCTCATTTAAATGCTTTCTTACA
TGATAGTGAGTTAATCTCTTATTCTCGTTTGACCAAAACGATTCGAGCGGATAATGTCATCGGTTGGGGATTACGCCCTT
CTGCGGGCAAAGCTCGTGCTTATGCCGAACAACATTATCTTCCTTATATTGCATTAGAAGACGGTTTTTTACGTTCGCTC
GGGCTGGGTGTTATGGGCTATCCGCCTTTCTCCGTTGTGTATGATGATGTCGGTATTTATTACGACACGACACGTTCATC
CCGCTTAGAGCAGCTGATTCTCAGTTCGCATTTTAGCGCAACCGATCTTCAACAGGCGGAGCAAGCCGTGCGGCTAATTG
TTCGTCATCAGTTATCAAAATATAACCATAATCCTGATTATGTTTCCAATGGACCGAAAACAAGTGAAATCGTATTAGTC
ATAGATCAAACCTTTGGTGATATGGCGGTAAAATACGGTCGGGCGAATGAATCCGATTTCCAACAAATGCTGGATGCGGC
GATTGGTGAAAATCCCGATGCTCAAATTTGGGTAAAAACGCATCCGGATGTAATTAGCGGAAAGAAAAAAGGTTATTTAA
CCGATTTACATCGTTACGGTAACCGAATTCGTTTATTCGCGGAAGACGTTAATCCGATCTCTCTGTTGAATCGGATTGAT
AAGGTCTATTGCGTTACTTCACAGATGGGATTTGAGGCGCTACTGTTAGGTAAACCGGTGATTACGTTTGGTATTCCTTG
GTTTGCCGGCTGGGGAGTAACGGAAGACAGACATCCGGATATTGATGTGTTAAAGCGTTCGCAACGTCGTGAGAATCGTT
CTTTTCTGCAATTGTTTGCCGCAGCTTACCTACAATATAGCCGTTATATTAATCCGTATTCGGGAAAAGTCGGTACGATT
TTTGATGTTATCGATTATCTGAGCAAAGCGAAAATATTGAATCAACGTTTAGGTGGGCATCTCTATTGTATTGGAATGTC
ATTATGGAAACGAGCTGTGATTAAGCCGTTTTTCAATTTGCCTTTATGCCAGTTACATTTTGTCGGCTCATTAAAAACGT
TGGAAAAAAGAACGCTTGAAAAAGATGCTAAATTATTAATTTGGAGCCAAGGAAAACCGGAAGTGTTAGCTTATTCTGAA
AAGCATCATATTCCGCTTTTACGTATGGAAGACGGCTTTATTCGATCTGTCGGCCTGGGATCTAATTTAGTTGCACCGTT
ATCATTGGTGATTGATGATTTAGGTATTTATTTTAATGCACAAACGCCTTCTCGTTTAGAAGAGATTTTATTGCATCAAG
AATTTAGTGAGCAGGATTTAGTCCTAGCGAAAAAATTACAAACTCGCTTATTAGAAGCAAATATCGGCAAATATAATGTG
GGAAGTGCCGGCTTCCAACTTAATGTCACGGATAAACGTACCATTTTAGTACCCGGTCAGGTGGAAGATGACGCTTCTAT
TCGTTTCGGTTCTCCGGAAATTAAGAAAAATTTGGATTTGTTGCGTAAGGTTAGAGAATTAAATCCTAATGCTTACATTA
TTTATAAACCGCATCCGGATGTAGTTAGCGGTAATCGACAAGGGCATATACCGACCGAACAAGCGGTCGAATTTGCCGAT
GAAATTGTCGAAAACGCCAATATCTTAGACTGCATTAACCAAGTTGATGAAGTACATACGATGACCTCATTAGCCGGTTT
CGAAGCTCTATTACGTGGGAAAATCGTGCATTGTTACGGACTGCCTTTTTATTCGAATTGGGGATTAACCGAAGATTATC
TTTCGCTTGAACGTCGTCACAGAAAGTTATGTTTGGAAGAACTTATTTCGGCGGTACTGGTATATTATCCTCAATATGTC
GATCCGGAAAATGCGACAATGATTAATGCGGAACAAGCGATTGAAATTCTGCAACAACAAAAACAACAGCTATCACATAG
CGGTATTAAACGTCCGTGGATCGCCAAACAGTTTGGTAAATTGAAACAGCTTTATCGCACATTGCAATAA

Protein sequence : 
MAQCSITKSLIFSRGILKIPHLNAFLHDSELISYSRLTKTIRADNVIGWGLRPSAGKARAYAEQHYLPYIALEDGFLRSL
GLGVMGYPPFSVVYDDVGIYYDTTRSSRLEQLILSSHFSATDLQQAEQAVRLIVRHQLSKYNHNPDYVSNGPKTSEIVLV
IDQTFGDMAVKYGRANESDFQQMLDAAIGENPDAQIWVKTHPDVISGKKKGYLTDLHRYGNRIRLFAEDVNPISLLNRID
KVYCVTSQMGFEALLLGKPVITFGIPWFAGWGVTEDRHPDIDVLKRSQRRENRSFLQLFAAAYLQYSRYINPYSGKVGTI
FDVIDYLSKAKILNQRLGGHLYCIGMSLWKRAVIKPFFNLPLCQLHFVGSLKTLEKRTLEKDAKLLIWSQGKPEVLAYSE
KHHIPLLRMEDGFIRSVGLGSNLVAPLSLVIDDLGIYFNAQTPSRLEEILLHQEFSEQDLVLAKKLQTRLLEANIGKYNV
GSAGFQLNVTDKRTILVPGQVEDDASIRFGSPEIKKNLDLLRKVRELNPNAYIIYKPHPDVVSGNRQGHIPTEQAVEFAD
EIVENANILDCINQVDEVHTMTSLAGFEALLRGKIVHCYGLPFYSNWGLTEDYLSLERRHRKLCLEELISAVLVYYPQYV
DPENATMINAEQAIEILQQQKQQLSHSGIKRPWIAKQFGKLKQLYRTLQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lipA NP_273145.1 capsule polysaccharide modification protein Not tested IHT-A Protein 0.0 61
kpsC YP_854335.1 capsule polysaccharide export protein KpsC Not tested PAI I APEC-O1 Protein 1e-141 50
kpsC AAZ04470.1 capsule polysaccharide export protein Virulence PAI I APEC-O1 Protein 9e-142 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lipA2 YP_001652723.1 capsule polysaccharide modification protein VFG0704 Protein 0.0 63
lipA2 YP_001652723.1 capsule polysaccharide modification protein VFG0692 Protein 0.0 63
lipA2 YP_001652723.1 capsule polysaccharide modification protein VFG0259 Protein 0.0 61